Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Paul D, Dobson"'
Publikováno v:
AIMS Bioengineering, Vol 5, Iss 1, Pp 1-38 (2018)
Sources of methane are numerous, and vary greatly in their use and sustainable credentials. A Jekyll and Hyde character, it is a valuable energy source present as geological deposits of natural gas, however it is also potent greenhouse gas, released
Externí odkaz:
https://doaj.org/article/15b0ba4246c342a0ab097777f511dec9
Autor:
Neil Swainston, Riza Batista-Navarro, Pablo Carbonell, Paul D Dobson, Mark Dunstan, Adrian J Jervis, Maria Vinaixa, Alan R Williams, Sophia Ananiadou, Jean-Loup Faulon, Pedro Mendes, Douglas B Kell, Nigel S Scrutton, Rainer Breitling
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179130 (2017)
Biologists and biochemists have at their disposal a number of excellent, publicly available data resources such as UniProt, KEGG, and NCBI Taxonomy, which catalogue biological entities. Despite the usefulness of these resources, they remain fundament
Externí odkaz:
https://doaj.org/article/ce135720eff6478e9e5ad7cd843981b6
Autor:
Benjamin Strutton, Stephen RP Jaffe, Caroline A Evans, Gregory JS Fowler, Paul D Dobson, Jagroop Pandhal, Phillip C Wright
Publikováno v:
Bioengineering, Vol 6, Iss 1, p 27 (2019)
Escherichia coli strains have been modified in a variety of ways to enhance the production of different recombinant proteins, targeting membrane protein expression, proteins with disulphide bonds, and more recently, proteins which require N-linked gl
Externí odkaz:
https://doaj.org/article/71fd78d5669f436cb4bdfdb85dd45afc
Autor:
Jerry Clifford, Carolanne Doherty, David C. James, Paul D. Dobson, Ben Thompson, Karen P. Coss
Publikováno v:
Biotechnology and Bioengineering
In cell line development the identification of stable Chinese hamster ovary cells for production is a critical but onerous task. The stability trial focus upon high‐level attributes can mask profound underlying cellular changes, leading to unstable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef3f7c7cddb2506d6706866e1d2c06f
https://doi.org/10.1002/bit.27336
https://doi.org/10.1002/bit.27336
Publikováno v:
AIMS Bioengineering, Vol 5, Iss 1, Pp 1-38 (2018)
Sources of methane are numerous, and vary greatly in their use and sustainable credentials. A Jekyll and Hyde character, it is a valuable energy source present as geological deposits of natural gas, however it is also potent greenhouse gas, released
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35004f5205b860ee9bf7359f198702f3
https://doi.org/10.3934/bioeng.2018.1.1
https://doi.org/10.3934/bioeng.2018.1.1
Autor:
Natalie J, Stanford, Martin, Scharm, Paul D, Dobson, Martin, Golebiewski, Michael, Hucka, Varun B, Kothamachu, David, Nickerson, Stuart, Owen, Jürgen, Pahle, Ulrike, Wittig, Dagmar, Waltemath, Carole, Goble, Pedro, Mendes, Jacky, Snoep
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2049
Computational systems biology involves integrating heterogeneous datasets in order to generate models. These models can assist with understanding and prediction of biological phenomena. Generating datasets and integrating them into models involves a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::689a90901a87bc461fda4c292a10a7f7
https://pubmed.ncbi.nlm.nih.gov/31602618
https://pubmed.ncbi.nlm.nih.gov/31602618
Autor:
Jagroop Pandhal, Caroline A. Evans, Phillip C. Wright, G. J. S. Fowler, Benjamin Strutton, Stephen R.P. Jaffé, Paul D. Dobson
Publikováno v:
Bioengineering
Volume 6
Issue 1
Bioengineering, Vol 6, Iss 1, p 27 (2019)
Bioengineering, 6(1):27
Volume 6
Issue 1
Bioengineering, Vol 6, Iss 1, p 27 (2019)
Bioengineering, 6(1):27
Escherichia coli strains have been modified in a variety of ways to enhance the production of different recombinant proteins, targeting membrane protein expression, proteins with disulphide bonds, and more recently, proteins which require N-linked gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b495ad84f2decb841211c90a14e8b9
BackgroundIn metabolic network reconstruction the stoichiometric balancing of reactions is essential to create realistic constraint-based models. At the genome scale, balancing is a repetitive task that consumes valuable curator resource that could b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15928caebc5eaf334820ede50d071588
Publikováno v:
Drug Discovery Today. 18:218-239
A recent paper in this journal sought to counter evidence for the role of transport proteins in effecting drug uptake into cells, and questions that transporters can recognize drug molecules in addition to their endogenous substrates. However, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8478f2d35c73fdc33aba81af96cc9ced
https://doi.org/10.1016/j.drudis.2012.11.008
https://doi.org/10.1016/j.drudis.2012.11.008
Autor:
Pedro Mendes, Dong-Yup Lee, Michael Hanscho, Nathan E. Lewis, Douglas B. Kell, Meiyappan Lakshmanan, Jahir M. Gutierrez, Alex Thomas, Natalie J. Gardiner, Joanne K. Liu, Shangzhong Li, Paul D. Dobson, Juergen Zanghellini, Hooman Hefzi, Kok Siong Ang, Camila A. Orellana, Veronica Martinez, Neil Swainston, Nicole Borth, Lars K. Nielsen, Daniel C. Zielinski, Kieran Smallbone, Sarantos Kyriakopoulos, Judy Brewer, Lake-Ee Quek
Publikováno v:
Springer US
Metabolomics : Official journal of the Metabolomic Society, vol 12, iss 7
Metabolomics
Swainston, N, Smallbone, K, Hefzi, H, Dobson, P D, Brewer, J, Hanscho, M, Zielinski, D C, Ang, K S, Gardiner, N, Gutierrez, J M, Kyriakopoulos, S, Lakshmanan, M, Li, S, Liu, J K, Martínez, V S, Orellana, C A, Quek, L-E, Thomas, A, Zanghellini, J, Borth, N, Lee, D-Y, Nielsen, L K, Kell, D, Lewis, N E & Mendes, P 2016, ' Recon 2.2 : from reconstruction to model of human metabolism ', Metabolomics : Official journal of the Metabolomic Society, vol. 12, pp. 109 . https://doi.org/10.1007/s11306-016-1051-4
Swainston, N, Smallbone, K, Hefzi, H, Dobson, P D, Brewer, J, Hanscho, M, Zielinski, D C, Ang, K S, Gardiner, N J, Gutierrez, J M, Kyriakopoulos, S, Lakshmanan, M, Li, S, Liu, J K, Martínez, V S, Orellana, C A, Quek, L E, Thomas, A, Zanghellini, J, Borth, N, Lee, D Y, Nielsen, L K, Kell, D B, Lewis, N & Mendes, P 2016, ' Recon 2.2 : from reconstruction to model of human metabolism ', Metabolomics, vol. 12, 109 . https://doi.org/10.1007/s11306-016-1051-4
Metabolomics : Official journal of the Metabolomic Society, vol 12, iss 7
Metabolomics
Swainston, N, Smallbone, K, Hefzi, H, Dobson, P D, Brewer, J, Hanscho, M, Zielinski, D C, Ang, K S, Gardiner, N, Gutierrez, J M, Kyriakopoulos, S, Lakshmanan, M, Li, S, Liu, J K, Martínez, V S, Orellana, C A, Quek, L-E, Thomas, A, Zanghellini, J, Borth, N, Lee, D-Y, Nielsen, L K, Kell, D, Lewis, N E & Mendes, P 2016, ' Recon 2.2 : from reconstruction to model of human metabolism ', Metabolomics : Official journal of the Metabolomic Society, vol. 12, pp. 109 . https://doi.org/10.1007/s11306-016-1051-4
Swainston, N, Smallbone, K, Hefzi, H, Dobson, P D, Brewer, J, Hanscho, M, Zielinski, D C, Ang, K S, Gardiner, N J, Gutierrez, J M, Kyriakopoulos, S, Lakshmanan, M, Li, S, Liu, J K, Martínez, V S, Orellana, C A, Quek, L E, Thomas, A, Zanghellini, J, Borth, N, Lee, D Y, Nielsen, L K, Kell, D B, Lewis, N & Mendes, P 2016, ' Recon 2.2 : from reconstruction to model of human metabolism ', Metabolomics, vol. 12, 109 . https://doi.org/10.1007/s11306-016-1051-4
Introduction The human genome-scale metabolic reconstruction details all known metabolic reactions occurring in humans, and thereby holds substantial promise for studying complex diseases and phenotypes. Capturing the whole human metabolic reconstruc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332345c15f1913df42ed1712fe112ec0
https://doi.org/10.1007/s11306-016-1051-4
https://doi.org/10.1007/s11306-016-1051-4