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of 4
pro vyhledávání: '"Paul Cuddon"'
Autor:
PAUL CUDDON, MARTIN D BOOTMAN, GILLIAN R RICHARDS, ALISON J SMITH, PETER B SIMPSON, H LLEWELYN RODERICK
Publikováno v:
Biological Research, Vol 41, Iss 2, Pp 183-195 (2008)
Neurons are a diverse cell type exhibiting hugely different morphologies and neurotransmitter specifications. Their distinctive phenotypes are established during differentiation from pluripotent precursor cells. The signalling pathways that specify t
Externí odkaz:
https://doaj.org/article/5b2950a7db644d21b4067656dd054e83
Autor:
Jey W. Koehler, Ashley N. Randle, Jillian Gallagher, Amanda L. Gross, Elise B. Diffie, Brett D. Story, Sundeep Chandra, Sara Carl, Kayly Nielsen, Paul Cuddon, Miguel Sena-Esteves, Edwin H. Kolodny, Deborah Fernau, Amanda R. Taylor, Douglas R. Martin, Carly Corado, Xuntian Jiang, Heather L. Gray-Edwards, Annie S. Maguire, Toloo Taghian, Siauna Johnson
Publikováno v:
Mol Genet Metab
Tay-Sachs disease (TSD) is a fatal neurodegenerative disease caused by a deficiency of the enzyme β-N-acetylhexosaminidase A (HexA). TSD naturally occurs in Jacob sheep is the only experimental model of TSD. TSD in sheep recapitulates neurologic fea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a0c7cda10ecdd0ead870203e1fd7ba
https://europepmc.org/articles/PMC8811770/
https://europepmc.org/articles/PMC8811770/
Autor:
Angeleen Fleming, David C. Rubinsztein, Andrea Williams, R.A. Floto, Cahir J. O'Kane, Paul Cuddon, Shinji Saiki, Luca Jahreiss, Dean Pask, Evangelia K. Ttofi, Sovan Sarkar, Paul Goldsmith, Farah H. Siddiqi
Autophagy is a major clearance route for intracellular aggregate-prone proteins causing diseases such as Huntington's disease. Autophagy induction with the mTOR inhibitor rapamycin accelerates clearance of these toxic substrates. As rapamycin has non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e43282b638402c45c2b7b586f00e84
https://europepmc.org/articles/PMC2635566/
https://europepmc.org/articles/PMC2635566/
Autor:
Peter B. Simpson, Martin D. Bootman, H. Llewelyn Roderick, Paul Cuddon, Gillian R. Richards, Alison J. Smith
Publikováno v:
BASE-Bielefeld Academic Search Engine
Biological Research, Vol 41, Iss 2, Pp 183-195 (2008)
Biological Research, Volume: 41, Issue: 2, Pages: 183-195, Published: 2008
Biological Research v.41 n.2 2008
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Vol 41, Iss 2, Pp 183-195 (2008)
Biological Research, Volume: 41, Issue: 2, Pages: 183-195, Published: 2008
Biological Research v.41 n.2 2008
SciELO Chile
CONICYT Chile
instacron:CONICYT
Neurons are a diverse cell type exhibiting hugely different morphologies and neurotransmitter specifications. Their distinctive phenotypes are established during differentiation from pluripotent precursor cells. The signalling pathways that specify t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85afaacfe569db9615afd2319b0dbaff
https://doaj.org/article/5b2950a7db644d21b4067656dd054e83
https://doaj.org/article/5b2950a7db644d21b4067656dd054e83