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pro vyhledávání: '"Paul Consroe"'
Autor:
Paul Consroe
Publikováno v:
Neurobiology of Disease, Vol 5, Iss 6, Pp 534-551 (1998)
Unprecedented developments in cannabinoid research within the past decade include discovery of a brain (CB1) and peripheral (CB2) receptor; endogenous ligands, anandamide, and 2-arachidonylglycerol; cannabinoid drug-induced partial and inverse agonis
Externí odkaz:
https://doaj.org/article/33c83ed3a325461a9c774a058d3137f0
Autor:
Paul Consroe, Stuart R. Snider
Publikováno v:
Cannabinoids as Therapeutic Agents ISBN: 9780429260667
Medicinal marijuana, like hedonic marijuana, has progressed from empirical use and anecdotal reports to the more critical scrutiny of modern scientific investigation. Nevertheless, the historical accounts of the properties of marijuana have provided
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a594afb56c5a634d5cdcb9e684cc2775
https://doi.org/10.1201/9780429260667-2
https://doi.org/10.1201/9780429260667-2
Publikováno v:
Scopus-Elsevier
Fifty-three UK and 59 USA people with multiple sclerosis (MS) answered anonymously the first questionnaire on cannabis use and MS. From 97 to 30% of the subjects reported cannabis improved (in descending rank order): spasticity, chronic pain of extre
Publikováno v:
Life Sciences. 56:1933-1940
Publikováno v:
Journal of Wilderness Medicine. 3:162-167
An intravenous dose-lethality study of 14 clinically important North and South American pit viper venoms was carried out in mice using standardized, rigorous protocols developed to meet international (WHO) guidelines and US government (FDA) regulatio
Autor:
Lawrence Z. Stern, James Allender, Stuart R. Snider, Reuven Sandyk, Kurt Kennedy, Joan Laguna, Paul Consroe, Karl H. Schram
Publikováno v:
Pharmacology Biochemistry and Behavior. 40:701-708
Based on encouraging preliminary findings, cannabidiol (CBD), a major nonpsychotropic constituent of Cannabis, was evaluated for symptomatic efficacy and safety in 15 neuroleptic-free patients with Huntington's Disease (HD). The effects of oral CBD (
Autor:
Alexandros Makriyannis, Keiko Hosohata, Raymond M. Quock, Paul Consroe, William R. Roeske, Yoshiaki Hosohata, Henry I. Yamamura
Publikováno v:
European Journal of Pharmacology. 321:R1-R3
This research was designed to determine the action of the novel aminoalkylindole AM630 (6-iodo-pravadoline) at the cannabinoid receptor by studying its interaction with the cannabinoid receptor agonist WIN 55,212-2 (R(+)-[2,3-dihydro-5-methyl-3-[(mor
Autor:
Paul Consroe
Publikováno v:
Marihuana and Medicine ISBN: 9781475757170
Recently, the subject of medical marihuana has received an extraordinary amount of attention. This issue has been discussed and scrutinized in the lay media and at several medical and scientific venues in the United States and United Kingdom. Many of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ad7394291254b630439e2bc83f23270
https://doi.org/10.1007/978-1-59259-710-9_60
https://doi.org/10.1007/978-1-59259-710-9_60
Autor:
Henry I. Yamamura, Hongfeng Deng, Robert S. Landsman, William R. Roeske, Alexandros Makriyannis, Paul Consroe
Publikováno v:
Life sciences. 62(9)
The present investigation examines WIN 55,212-2 and AM630 at the cloned human cannabinoid CB1 receptor stably expressed in Chinese hamster ovary (CHO) cells. The effect of various concentrations of WIN 55,212-2 and AM630 on basal [35S]GTPgammaS bindi
Autor:
Frederick J. Ehlert, Thomas H Burkey, Paul Consroe, William R. Roeske, Yoshiaki Hosohata, Henry I. Yamamura, Raymond M. Quock
Publikováno v:
European journal of pharmacology. 336(2-3)
We measured (-)-5-(1,1-dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohe xyl]-phenol (CP 55,940)-, (-)11-OH-delta8-tetrahydrocannabinol-dimethylheptyl (HU-210)-, anandamide- and delta9-tetrahydrocannabinol-stimulated G protein activation in mou