Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Paul Comfurius"'
Autor:
Edouard M. Bevers, Jef L. N. Wolfs, Robert F. A. Zwaal, Krishnakumar Balasubramanian, Theo Lindhout, Alan J. Schroit, Otto Bekers, Paul Comfurius
Publikováno v:
Cellular and Molecular Life Sciences, 66(2), 314-23. Springer
The exposure of phosphatidylserine (PS) at the cell surface plays a critical role in blood coagulation and serves as a macrophage recognition moiety for the engulfment of apoptotic cells. Previous observations have shown that a high extracellular [K(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d7f1ac7e7b62e434ed1c7e05fd69e1
https://doi.org/10.1007/s00018-008-8566-4
https://doi.org/10.1007/s00018-008-8566-4
Autor:
Jocelyne Enouf, Robert F. A. Zwaal, Edouard M. Bevers, H. K. Nieuwenhuis, Sylviane Levy-Toledano, S. Belluci, Paul Comfurius, J.P. Caen
Publikováno v:
British Journal of Haematology. 63:335-345
Prothrombinase activities of platelets have been measured in diluted platelet-rich plasma using a chromogenic substrate assay and purified coagulation factors. No abnormalities in prothrombinase activities were found for platelets from patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad71e48cf1040d61ba3626be31dd3e3d
https://doi.org/10.1111/j.1365-2141.1986.tb05557.x
https://doi.org/10.1111/j.1365-2141.1986.tb05557.x
Autor:
Paul Comfurius, Robert F. Zwaal, Simone J. Wielders, John C. Giddings, Jef L. N. Wolfs, Theo Lindhout, Edouard M. Bevers
Publikováno v:
Blood. 108:2223-2228
The platelet procoagulant response requires a sustained elevation of the intracellular Ca2+ concentration, [Ca2+]i, causing exposure of phosphatidylserine (PS) at the outer surface of the plasma membrane. An increased [Ca2+]i also activates Ca2+-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa56dfed52302c44c64e56b2bfcd5971
https://doi.org/10.1182/blood-2006-01-009613
https://doi.org/10.1182/blood-2006-01-009613
Autor:
Jan T. Rasmussen, Theo Lindhout, Edouard M. Bevers, J. F. W. Keuren, Robert F. A. Zwaal, Jef L. N. Wolfs, Paul Comfurius
Publikováno v:
Cellular and Molecular Life Sciences. 62:1514-1525
Platelet procoagulant activity is mainly determined by the extent of surface-exposed phosphatidylserine (PS), controlled by the activity of aminophospholipid translocase and phospholipid scramblase. Here, we studied both transport activities in singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd07b03916b2596a7f411f07e3ea970
https://doi.org/10.1007/s00018-005-5099-y
https://doi.org/10.1007/s00018-005-5099-y
Autor:
Robert F. A. Zwaal, Krishnakumar Balasubramanian, Marie P. Janssen, Paul Comfurius, George M. Willems, Edouard M. Bevers, Alan J. Schroit
Publikováno v:
Biochemical Journal. 386:271-279
The plasma protein β2GPI (β2-glycoprotein I) has been proposed to mediate phagocytosis of apoptotic cells and to play a role in the antiphospholipid syndrome. This suggestion is based mainly on the presumption that β2GPI has an appreciable interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762f077d74f559f8b30193e0f667087d
https://doi.org/10.1042/bj20041167
https://doi.org/10.1042/bj20041167
Publikováno v:
Molecular Membrane Biology. 20:83-91
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddbe4a6ecf39c728b5e3c9ca0a90343f
https://doi.org/10.1080/09687680307079
https://doi.org/10.1080/09687680307079
Autor:
Peter William Collins, Imke C. A. Munnix, John C. Giddings, Marjan Harmsma, Edouard M. Bevers, Johan W. M. Heemskerk, Marion A.H. Feijge, Paul Comfurius
Publikováno v:
Thrombosis and Haemostasis. 89:687-695
SummaryScott syndrome is a bleeding disorder, characterized by impaired surface exposure of procoagulant phosphatidylserine (PS) on platelets and other blood cells, following activation with Ca2+-elevating agents. Since store-mediated Ca2+ entry (SMC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c6f22c11e17007037cb590bd6f2e725
https://doi.org/10.1055/s-0037-1613576
https://doi.org/10.1055/s-0037-1613576
Publikováno v:
Molecular Membrane Biology. 20:83-91
Membrane-perturbing agents that cause transformation of biconcave erythrocytes into echinocytes or stomatocytes were used to investigate the influence of erythrocyte shape on the rate of Ca(2+)-induced scrambling of phospholipids. Erythrocytes were t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be31a634f64762101d395f56246c1028
https://doi.org/10.1080/0968768031000064444
https://doi.org/10.1080/0968768031000064444
Autor:
Marie P. Janssen, Paul Comfurius, Edouard M. Bevers, Monica Galli, George M. Willems, Robert F. A. Zwaal
Publikováno v:
Biochemistry. 41:14357-14363
Antiphospholipid antibodies interact with phospholipid membranes via lipid binding plasma proteins, mostly, prothrombin and beta(2)-glycoprotein I. Using ellipsometry, we characterized prothrombin-mediated binding of lupus anticoagulant (LA) positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb8fbd26c57d04888d18ad200d6fe0d
https://doi.org/10.1021/bi026408l
https://doi.org/10.1021/bi026408l
Publikováno v:
Biochemical Journal. 362:741-747
Treatment of red blood cells with calcium and ionomycin causes activation of the lipid scramblase, a putative membrane protein catalysing flip-flop of (phospho)lipids. Various fluorescent 1-oleoyl-2-[6(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino] caproyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9e8a17a32e0cf18ea1823b55d642cc4
https://doi.org/10.1042/bj3620741
https://doi.org/10.1042/bj3620741