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pro vyhledávání: '"Paul Coffer"'
Autor:
Enric Mocholi, Laura Russo, Keshav Gopal, Andrew Ramstead, Sophia M. Hochrein, HarmJan Vos, Geert Geeven, Adeolu Adegoke, Anna Hoekstra, Robert van Es, José Ramos Pittol, Sebastiaan Vastert, Jared Rutter, Timothy Radstake, Jorg van Loosdregt, Celia Berkers, Michal Mokry, Colin Anderson, Ryan O'Connell, Martin Vaeth, John Ussher, Boudewijn Burgering, Paul Coffer
Upon antigen-specific T Cell Receptor (TCR) engagement, human CD4+ T cells proliferate and differentiate, a process associated with rapid transcriptional changes and metabolic reprogramming. Here, we show that generation of extra-mitochondrial pyruva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b71b2a137c6e61ad219ab6d4149ac04
https://doi.org/10.21203/rs.3.rs-1324599/v1
https://doi.org/10.21203/rs.3.rs-1324599/v1
Autor:
Tjander Maikoe, Niels Geijsen, Jan-Willem J. Lammers, Leo Koenderman, Laura M'rabet, J. Paul Coffer, C. Rene Schweizer, A. M. Jan Raaijmakers
Publikováno v:
Biochemical Journal. 329:121-130
Although it is known that many stimuli can activate mitogen-activated protein kinases (MAPKs) and phosphatidylinositol 3-kinases (PI3K) in human neutrophils, little is known concerning either the mechanisms or function of this activation. We have uti