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of 5
pro vyhledávání: '"Paul Ciero"'
Autor:
Matthew E. Randolph, Marwa Afifi, Aparna Gorthi, Rachel Weil, Breelyn A. Wilky, Joshua Weinreb, Paul Ciero, Natalie ter Hoeve, Paul J. van Diest, Venu Raman, Alexander J.R. Bishop, David M. Loeb
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108925- (2024)
Summary: We previously demonstrated that RNA helicase DDX3X (DDX3) can be a therapeutic target in Ewing sarcoma (EWS), but its role in EWS biology remains unclear. The present work demonstrates that DDX3 plays a unique role in DNA damage repair (DDR)
Externí odkaz:
https://doaj.org/article/feee3811ebda42bda24ca7644f0ec5fe
Publikováno v:
Cancer Research. 83:6725-6725
Introduction: Osteosarcoma (OS) is the most common primary malignant bone tumor in adolescents and young adults. Intensive multimodal treatment cures almost 75% of patients who present with localized disease; however, only 25% of patients who present
Autor:
Noboru Asada, Sandra Pinho, Xizhe Wang, Avigdor Leftin, Paul S. Frenette, Maria Maryanovich, Fumio Nakahara, Halley Pierce, Qiaozhi Wei, Paul Ciero, Jianing Xu, Ali H. Zahalka
Publikováno v:
Nature medicine
Nat Med
Nat Med
Aging of hematopoietic stem cells (HSCs) is associated with a decline in their regenerative capacity and multilineage differentiation potential, contributing to the development of blood disorders. The bone marrow microenvironment has recently been su
Autor:
Paul Ciero, Ali H. Zahalka, Sandra Pinho, Fumio Nakahara, Maria Maryanovich, Avigdor Leftin, Halley Pierce, Jianing Xu, Qiaozhi Wei, Noboru Asada, Paul S. Frenette, Xizhe Wang
Publikováno v:
Nature Medicine. 25:701-701
In the version of this article originally published, the key for Fig. 4c was incorrect. The symbols for 'Sham' and 'Den' were reversed. The error has been corrected in the PDF and HTML versions of the manuscript.
Autor:
Jalal A. Khan, Paul Ciero, Yuya Kunisaki, Anna Arnal-Estapé, Avi Ma'ayan, Miriam Merad, Avital Mendelson, Sandra Pinho, Paul S. Frenette, Fumio Nakahara, Yan Kou, Alexander Birbrair, Aviv Bergman
Publikováno v:
Science (New York, N.Y.). 351(6269)
How HSCs populate the fetal liver Hematopoietic stem cells (HSCs) undergo dramatic expansion in the fetal liver before migrating to their definitive site in the bone marrow. Khan et al. identify portal vessel–associated Nestin + NG2 + pericytes as