Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Paul Childress"'
Autor:
Safa F. Mohamad, Deepa Kanagasabapathy, Jung Min Hong, Angela Bruzzaniti, Paul Childress, Rachel J. Blosser, Joydeep Ghosh, Jianyun Liu, Alexandra Aguilar-Perez, Melissa A. Kacena, Andrea M. Gunawan, Edward F. Srour
Publikováno v:
J Bone Miner Res
Osteomacs (OM) are specialized bone-resident macrophages that are a component of the hematopoietic niche and support bone formation. Also located in the niche are a second subset of macrophages, namely bone marrow-derived macrophages (BM Mφ). We pre
Autor:
Bintu Sowe, George Dimitrov, Aarti Gautam, Aamir Tucker, Liming Zhao, Melissa A. Kacena, Ross Campbell, Stephen K. Mendenhall, Rasha Hammamieh, Nabarun Chakraborty, Paul Childress, Ariane Zamarioli
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3507-3520 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Adverse effects of spaceflight on musculoskeletal health increase the risk of bone injury and impairment of fracture healing. Its yet elusive molecular comprehension warrants immediate attention, since space travel is becoming more frequent. Here we
Autor:
Nabarun Chakraborty, Paul Childress, Michael Savaglio, George Dimitrov, Allison Hoke, Aarti Gautam, Bintu Sowe, David L. Waning, Raina Kumar, Rasha Hammamieh, Dana Youssef, Candace Moyler, Melissa A. Kacena, Stephan Butler
Publikováno v:
Journal of Bone and Mineral Research
Prolonged residence of mice in spaceflight is a scientifically robust and ethically ratified model of muscle atrophy caused by continued unloading. Under the Rodent Research Program of the National Aeronautics and Space Administration (NASA), we assa
Autor:
Evan R. Himes, Kevin A. Maupin, Joydeep Ghosh, Louis M. Pelus, Christie M. Orschell, Paul Childress, Alexa Fisher, Marta B. Alvarez, Jung Min Hong, Irushi Abeysekera, Edward F. Srour, Pratibha Singh, Artur P. Plett, Safa F. Mohamad, Carol H. Sampson, Melissa A. Kacena, Angela Bruzzaniti, Hui Lin Chua
Publikováno v:
Bone
Osteoblast number and activity decreases with aging, contributing to the age-associated decline of bone mass, but the mechanisms underlying changes in osteoblast activity are not well understood. Here, we show that the age-associated bone loss critic
Autor:
Tien-Min G. Chu, Roman M. Natoli, Paul Childress, Karl D Shively, Michael K Savaglio, Emily Jewell, Austin E. Wininger, Adam Gremah, Stuart J. Warden, Aamir Tucker, Jeffrey O. Anglen, Robyn K. Fuchs, Todd O. McKinley, Melissa A. Kacena, Kaitlyn S. Griffin
Publikováno v:
Mil Med
Introduction Segmental bone defects (SBDs) are devastating injuries sustained by warfighters and are difficult to heal. Preclinical models that accurately simulate human conditions are necessary to investigate therapies to treat SBDs. We have develop
Autor:
null Safa F. Mohamad, null Andrea Gunawan, null Rachel Blosser, null Paul Childress, null Alexandra Aguilar‐Perez, null Joydeep Ghosh, null Jung Min Hong, null Jianyun Liu, null Deepa Kanagasabapathy, null Melissa A. Kacena, null Edward F. Srour, null Angela Bruzzaniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87f24843c42f20ec3df5f1ff3e88864d
https://doi.org/10.1002/jbmr.4314/v3/response1
https://doi.org/10.1002/jbmr.4314/v3/response1
Autor:
Paul Childress, Aamir Tucker, Rasha Hammamieh, David C. Scofield, Austin E. Wininger, Melissa A. Kacena, Aarti Gautam, Jeffery D. Rytlewski, Nabarun Chakraborty, Kevin A. Maupin, Jonathan S. Harris, James P. Fischer, Ushashi C. Dadwal, Fazal Ur Rehman Bhatti, Marta B. Alvarez, Ariane Zamarioli
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
Spaceflight results in reduced mechanical loading of the skeleton, which leads to dramatic bone loss. Low bone mass is associated with increased fracture risk, and this combination may compromise future, long-term, spaceflight missions. Here, we exam
Autor:
James A. Hamilton, Paul Childress, Amber L. Mosley, Nickolay Brustovetsky, Jagannath Misra, Keith R. Stayrook, Joseph M. Wallace, Angela Klunk, Ronald C. Wek, Joseph P. Bidwell, Yu Shao, Michele Adaway, Alexander G. Robling, David B. Burr, Deepak Vashishth, Kylie Jacobs, Yunlong Liu, Matthew R. Allen, Emily Wichern
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 316:E749-E772
A goal of osteoporosis therapy is to restore lost bone with structurally sound tissue. Mice lacking the transcription factor nuclear matrix protein 4 ( Nmp4, Zfp384, Ciz, ZNF384) respond to several classes of osteoporosis drugs with enhanced bone for
Autor:
Angela Bruzzaniti, Paul Childress, Joydeep Ghosh, Rachel J. Blosser, Alexandra Aguilar-Perez, Safa F. Mohamad, Melissa A. Kacena, Jung Min Hong, Deepa Kanagasabapathy, Edward F. Srour, Jianyun Liu, Andrea M. Gunawan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::001feaa01e7c64708ee5e6f325bb8940
https://doi.org/10.1002/jbmr.4314/v2/response1
https://doi.org/10.1002/jbmr.4314/v2/response1
Autor:
Alexander L Kuzma, Paul Childress, David C. Scofield, Todd O. McKinley, Roman M. Natoli, Tien-Min G. Chu, Rashad H. Usmani, Jeffrey D Rytlewski, Emily Jewell, Jeffrey O. Anglen, James P. Fischer, Kaitlyn S. Griffin, Melissa A. Kacena, Karl D Shively
Publikováno v:
Mil Med
Background and Objective Porcine translational models have become the gold-standard translational tool to study the effects of major injury and hemorrhagic shock because of their similarity to the human immunologic response to trauma. Segmental bone