Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Paul Calabresi"'
Publikováno v:
Clinical Cancer Research. 10:7655-7661
Purpose: Malignant mesothelioma (MM) is a cancer with uniformly poor responses to current therapeutic regimens. This study evaluates whether taurolidine, a novel antineoplastic agent, is effective against human MM cell lines and a murine model of hum
Autor:
Lazzaro Repetto, Lodovico Balducci, Paul Calabresi, Ignazio Carreca, Matti Aapro, Dominique Maraninchi
Publikováno v:
Critical Reviews in Oncology/Hematology. 45:123-128
Over 70% of the total incidence of cancer recorded in Europe in 1996 was in the elderly population (> or =60 years). Despite such high statistics, elderly cancer patients have often been denied the treatment that younger patients routinely receive. T
Autor:
James H. Wyche, John M. Sedivy, Panayotis Pantazis, Zhiyong Han, Kannan V. Balan, Paul Calabresi, Wenyi Wei, Stephen Dunaway, Eric A. Hendrickson, James W. Darnowski
Publikováno v:
Journal of Biological Chemistry. 277:17154-17160
Treatment of cells with the anti-cancer drug camptothecin (CPT) induces topoisomerase I (Top1)-mediated DNA damage, which in turn affects cell proliferation and survival. In this report, we demonstrate that treatment of the wild-type HCT116 (wt HCT11
Publikováno v:
Cancer Gene Therapy. 9:37-43
Publikováno v:
Cancer. 83:2008-2014
BACKGROUND Bleomycin produces lung fibrosis in a wide variety of species. In humans, it can cause significant morbidity and mortality when used to treat malignancies such as lymphoma and testicular carcinoma. In rodents, it has been extensively used
Autor:
Merrill J. Egorin, Paul Calabresi, Fred H. Hochberg, Michael Glantz, Lawrence D. Recht, Stephen Saris, Bernard F. Cole, Pam Mills, Wallace Akerley
Publikováno v:
Journal of Clinical Oncology. 16:1561-1567
PURPOSE Standard treatments for neoplastic meningitis are only modestly effective and are associated with significant morbidity. Isolated reports suggest that concurrent systemic and intrathecal (i.t.) therapy may be more effective than i.t. therapy
Autor:
Lorrin K Yee, Paul Calabresi, Milton H. Lipsky, Katharine A. Whartenby, Ming Y.W. Chu, Edwin N. Forman, Edward Chu, John Epstein, Scott M. Freeman, Tian M. Chen
Publikováno v:
Pharmacology. 56:318-326
An in vivo experimental model was developed to predict efficiently and accurately chemosensitivity of human tumors. Human cancer cells either from cultured cell lines or from patients’ tumors were injected directly into semipermeable polysulfone fi
Autor:
TianM Chen, Robert M. Levin, David Russel, Harry J. Wilbur, Robin De Wolf, Tracey Fletcher, Paul Calabresi, Ming Y.W. Chu, Shailendra Kumar, Miklos Gellai, John Zalcberg, Laura J. Mogavero, Mel H. Epstein, Milton H. Lipsky, Hemendra N. Bhargava, Gail G. Snitkoff, Wei-zheng. Zhang, Paul W. Finch, Walter Cosolo, Tamar J. Nicholas, Lorrin K Yee, Thomas Maciag, Ponnal Nambi, Stanley Friedman, Hyung-Min Kim, James Mandell
Publikováno v:
Pharmacology. 55:I-IV
Autor:
Milton H. Lipsky, Paul Calabresi, Ming Y.W. Chu, Thomas Maciag, TianM Chen, Lorrin K Yee, Mel H. Epstein, Paul W. Finch, Stanley Friedman
Publikováno v:
Pharmacology. 55:269-278
Interference with growth factor-receptor interactions may have particular relevance in efforts to intervene clinically in both autocrine and paracrine aspects of malignancy. Suramin is a synthetic anticancer agent that works, in part, by blocking the