Zobrazeno 1 - 10
of 280
pro vyhledávání: '"Paul COTTU"'
Autor:
Sylvie Giacchetti, Enora Laas, Thomas Bachelot, Jérome Lemonnier, Fabrice André, David Cameron, Judith Bliss, Sylvie Chabaud, Anne-Claire Hardy- Bessard, Magali Lacroix-Triki, Jean-Luc Canon, Marc Debled, Mario Campone, Paul Cottu, Florence Dalenc, Annabelle Ballesta, Frederique Penault-Llorca, Bernard Asselain, Elise Dumas, Fabien Reyal, Paul Gougis, Francis Lévi, Anne-Sophie Hamy
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105141- (2024)
Summary: Background: Circadian rhythms regulate cellular physiology and could influence the efficacy of endocrine therapy (ET) in breast cancer (BC). We prospectively tested this hypothesis within the UNIRAD adjuvant phase III trial (NCT01805271). Me
Externí odkaz:
https://doaj.org/article/9f42a221348c45659c954d1962e5d5fe
Autor:
Hélène Salaün, Lounes Djerroudi, Laura Haik, Anne Schnitzler, Guillaume Bataillon, Gabrielle Deniziaut, Ivan Bièche, Anne Vincent‐Salomon, Marc Debled, Paul Cottu
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract Everolimus is widely used in patients with advanced ER‐positive, HER2‐negative breast cancer. We looked at alterations in the PIK3CA/AKT/mTOR pathway in a multicenter cohort as potential biomarkers of efficacy. Patients with advanced ER
Externí odkaz:
https://doaj.org/article/53c363172074422ebc516d2dfdc2dc90
Autor:
Rania El-Botty, Ludivine Morriset, Elodie Montaudon, Zakia Tariq, Anne Schnitzler, Marina Bacci, Nicla Lorito, Laura Sourd, Léa Huguet, Ahmed Dahmani, Pierre Painsec, Heloise Derrien, Sophie Vacher, Julien Masliah-Planchon, Virginie Raynal, Sylvain Baulande, Thibaut Larcher, Anne Vincent-Salomon, Guillaume Dutertre, Paul Cottu, Géraldine Gentric, Fatima Mechta-Grigoriou, Scott Hutton, Keltouma Driouch, Ivan Bièche, Andrea Morandi, Elisabetta Marangoni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Resistance to endocrine treatments and CDK4/6 inhibitors is considered a near-inevitability in most patients with estrogen receptor positive breast cancers (ER + BC). By genomic and metabolomics analyses of patients’ tumours, metastasis-de
Externí odkaz:
https://doaj.org/article/b26393ab46f442b18957dda9286c9e24
Autor:
Paul Cottu, Alistair Ring, Hikmat Abdel-Razeq, Paolo Marchetti, Fatima Cardoso, Javier Salvador Bofill, Miguel Martín, Lakshmi Menon-Singh, Jiwen Wu, Michelino De Laurentiis
Publikováno v:
Breast, Vol 62, Iss , Pp 75-83 (2022)
Background: The phase IIIb CompLEEment-1 study evaluated ribociclib plus letrozole in patients with hormone receptor–positive (HR+), human epidermal growth factor receptor 2–negative (HER2–) advanced breast cancer (ABC). Outcomes were investiga
Externí odkaz:
https://doaj.org/article/2d9b2884c332471aba888c054b6dfef5
Publikováno v:
Breast, Vol 61, Iss , Pp 118-122 (2022)
Among stakeholders and decision-makers in advanced breast cancer, the demand for insights from real-world data (RWD) is increasing. Although RWD can be used to support decisions throughout different stages of a breast cancer drug's life cycle, barrie
Externí odkaz:
https://doaj.org/article/ee2e08f6a1344034bc519744dd38c139
Autor:
Elsa Caumette, Inès Vaz-Luis, Sandrine Pinto, Julie Havas, Thomas Bovagnet, Garazi Ruiz de Azua, Antonio Di Meglio, Anne-Laure Martin, Sibille Everhard, Paul Cottu, Laurence Vanlemmens, Christelle Jouannaud, Florence Lerebours, Agnès Dumas, Gwenn Menvielle
Publikováno v:
Current Oncology, Vol 28, Iss 5, Pp 3866-3875 (2021)
Return to work (RTW) after breast cancer is associated with improved quality of life. The link between household characteristics and RTW remains largely unknown. The aim of this study was to examine the effect of the family situation on women’s RTW
Externí odkaz:
https://doaj.org/article/b8b4c489c4e34059888f783f09cc4421
Autor:
Pietro Lapidari, Arnauld Gbenou, Julie Havas, Elise Martin, Barbara Pistilli, Anne-Laure Martin, Sibille Everhard, Charles Coutant, Paul Cottu, Anne Lesur, Florence Lerebours, Olivier Tredan, Laurence Vanlemmens, Christelle Jouannaud, Christelle Levy, Olivier Rigal, Marion Fournier, Fabrice Andre, Ines Vaz-Luis, Antonio Di Meglio
Publikováno v:
Breast, Vol 57, Iss , Pp 43-48 (2021)
We assessed long-term associations of Granulocyte-Colony Stimulating Factors (G-CSF) use with patient-reported outcomes (PROs) and hematologic toxicity among chemotherapy-treated, early-stage breast cancer patients in CANTO (NCT01993498).Among 2920 p
Externí odkaz:
https://doaj.org/article/ef4f2574efb14de2b2de94ef9c41d09a
Autor:
Lauren Darrigues, Jean-Yves Pierga, Alice Bernard-Tessier, Ivan Bièche, Amanda Bartolini Silveira, Marc Michel, Delphine Loirat, Paul Cottu, Luc Cabel, Coraline Dubot, Romain Geiss, Francesco Ricci, Anne Vincent-Salomon, Charlotte Proudhon, François-Clément Bidard
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-10 (2021)
Abstract Background Following the PALOMA-3 study results, the combination of palbociclib, a CDK4/6 inhibitor, with fulvestrant, a selective estrogen receptor degrader, has become a standard therapy in women with estrogen receptor-positive (ER+) HER2-
Externí odkaz:
https://doaj.org/article/89988fb8f03547508590ebccffb3a87d
Autor:
Céline Callens, Keltouma Driouch, Anaïs Boulai, Zakia Tariq, Aurélie Comte, Frédérique Berger, Lisa Belin, Ivan Bièche, Vincent Servois, Patricia Legoix, Virginie Bernard, Sylvain Baulande, Walid Chemlali, François-Clément Bidard, Virginie Fourchotte, Anne Vincent- Salomon, Etienne Brain, Rosette Lidereau, Thomas Bachelot, Mahasti Saghatchian, Mario Campone, Sylvie Giacchetti, Brigitte Sigal Zafrani, Paul Cottu
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-15 (2021)
Abstract Background Prognosis evaluation of advanced breast cancer and therapeutic strategy are mostly based on clinical features of advanced disease and molecular profiling of the primary tumor. Very few studies have evaluated the impact of metastat
Externí odkaz:
https://doaj.org/article/ad1f3e2cf70f4b9695dd17547b4a898c
Autor:
Khalil Saleh, Matthieu Carton, Véronique Dieras, Pierre-Etienne Heudel, Etienne Brain, Véronique D’Hondt, Audrey Mailliez, Anne Patsouris, Marie-Ange Mouret-Reynier, Anthony Goncalves, Jean Marc Ferrero, Thierry Petit, George Emile, Lionel Uwer, Marc Debled, Florence Dalenc, Christelle Jouannaud, Sylvain Ladoire, Marianne Leheurteur, Paul Cottu, Lucie Veron, Alexia Savignoni, Coralie Courtinard, Mathieu Robain, Suzette Delaloge, Elise Deluche
Publikováno v:
Breast, Vol 55, Iss , Pp 16-24 (2021)
Background: High Body mass index (BMI) is a risk factor for breast cancer among postmenopausal women and an adverse prognostic factor in early-stage. Little is known about its impact on clinical outcomes in patients with metastatic breast cancer (MBC
Externí odkaz:
https://doaj.org/article/4ac8fb7b567c42e6b4d485c16e32498d