Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Paul C. Trampont"'
Autor:
Joel Mathews, Lakshmi Amaravadi, Steven Eck, Lauren Stevenson, Yow-Ming C. Wang, Viswanath Devanarayan, John Allinson, Kelly Lundsten, Michele Gunsior, Yan G. Ni, Marc-Olivier Pepin, Audrey Gagnon, Curtis Sheldon, Paul C. Trampont, Virginia Litwin
Publikováno v:
AAPS Open, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract This conference report summarized a full-day workshop, “best practices for the development and fit-for-purpose validation of biomarker methods,” which was held prior to the American Association of Pharmaceutical Scientists (AAPS) PharmSc
Externí odkaz:
https://doaj.org/article/6add8307c1b945c58fa2e3d151a9d6b7
Publikováno v:
Cell Reports, Vol 10, Iss 3, Pp 307-316 (2015)
Cancer develops after the acquisition of a collection of mutations that together create the cancer phenotype. How collections of mutations work together within a cell and whether there is selection for certain combinations of mutations are not well u
Externí odkaz:
https://doaj.org/article/ef4eeeca110c40aab8baf913389085b1
Autor:
Steven Piccoli, Devangi Mehta, Alessandra Vitaliti, John Allinson, Shashi Amur, Steve Eck, Cherie Green, Michael Hedrick, Shirley Hopper, Allena Ji, Alison Joyce, Virginia Litwin, Kevin Maher, Joel Mathews, Kun Peng, Afshin Safavi, Yow-Ming Wang, Yan Zhang, Lakshmi Amaravadi, Nisha Palackal, Sai Thankamony, Chris Beaver, Eris Bame, Thomas Emrich, Christine Grimaldi, Jonathan Haulenbeek, Vellalore Kakkanaiah, David Lanham, Andrew Mayer, Paul C Trampont, Laurent Vermet, Naveen Dakappagari, Catherine Fleener, Fabio Garofolo, Cynthia Rogers, Shabnam Tangri, Yuanxin Xu, Meina Liang, Manoj Rajadhyaksha, Susan Richards, Becky Schweighardt, Shobha Purushothama, Daniel Baltrukonis, Jochen Brumm, Elana Cherry, Jason Delcarpini, Carol Gleason, Susan Kirshner, Robert Kubiak, Luying Pan, Michael Partridge, João Pedras-Vasconcelos, Qiang Qu, Venke Skibeli, Therese Solstad Saunders, Roland F Staack, Kay Stubenrauch, Al Torri, Daniela Verthelyi, Haoheng Yan, Boris Gorovits, Rachel Palmer, Mark Milton, Brian Long, Bart Corsaro, Vahid Farrokhi, Michele Fiscella, Neil Henderson, Vibha Jawa, Jim McNally, Rocio Murphy, Hanspeter Waldner, Tong-Yuan Yang
Publikováno v:
Bioanalysis. 11:2207-2244
The 2019 13th Workshop on Recent Issues in Bioanalysis (WRIB) took place in New Orleans, LA, USA on April 1–5, 2019 with an attendance of over 1000 representatives from pharmaceutical/biopharmaceutical companies, biotechnology companies, contract r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d81a589202e4c0b3c30c4ddc1d93790
https://doi.org/10.4155/bio-2019-0271
https://doi.org/10.4155/bio-2019-0271
Publikováno v:
Bioanalysis. 13(21)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74129762e89c17e6a1fdbba2c813249
https://pubmed.ncbi.nlm.nih.gov/34528829
https://pubmed.ncbi.nlm.nih.gov/34528829
Autor:
Paul C Trampont, Ghanashyam Sarikonda, Virginia Litwin, Laïla-Aïcha Hanafi, Vilma Decman, Anil Pahuja, Yongliang S Sun, Mélissa Mathieu, Michael Nathan Hedrick, Susan Reynolds, Steven Eck, Qiong Xue, Naveen Dakappagari, Jennifer J. Stewart, Shabnam Tangri, Mahwish Natalia, Piotr L Pierog
Publikováno v:
Cytometry. Part B, Clinical cytometryREFERENCES. 100(1)
Chimeric Antigen Receptor (CAR) T cells are recognized as efficacious therapies with demonstrated ability to produce durable responses in blood cancer patients. Regulatory approvals and acceptance of these unique therapies by patients and reimburseme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827a48da1ba65edc3eeaf1545aad0e60
https://pubmed.ncbi.nlm.nih.gov/33373096
https://pubmed.ncbi.nlm.nih.gov/33373096
Autor:
Ann Marie Pendergast, Jing J. Gu, Amber J. Giles, Li Zhang, Scott F. Walk, Paul C. Trampont, Kodi S. Ravichandran
Publikováno v:
Molecular and Cellular Biology. 35:1462-1476
Signaling via the pre-T-cell receptor (pre-TCR), along with associated signals from Notch and chemokine receptors, regulates the β-selection checkpoint that operates on CD4(-) CD8(-) doubly negative (DN) thymocytes. Since many hematopoietic malignan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd427cfc4db7a5f74862f480dc88251
https://doi.org/10.1128/mcb.01084-14
https://doi.org/10.1128/mcb.01084-14
Autor:
Ignacio J. Juncadella, Paul C. Trampont, Kodi S. Ravichandran, Sanja Arandjelovic, Aaron M. Fond, Monica W. Buckley
Publikováno v:
The Journal of Immunology. 194:1665-1676
T cell development in the thymus is a highly regulated process that critically depends upon productive signaling via the preTCR at the β-selection stage, as well as via the TCR for selection from the CD4+CD8+ double-positive stage to the CD4 or CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfd3883b871eef83687535410bcc22e
https://doi.org/10.4049/jimmunol.1401728
https://doi.org/10.4049/jimmunol.1401728
Autor:
Jeffrey J. Lysiak, Claudia Z. Han, Soumita Das, Jason M. Kinchen, Daeho Park, Sheila Collins, Kodi S. Ravichandran, Paul C. Trampont, Kyle L. Hoehn, Michael R. Elliott
Publikováno v:
Nature. 477:220-224
Rapid and efficient removal of apoptotic cells by phagocytes plays a key role during development, tissue homeostasis, and in controlling immune responses1–5. An important feature of efficient clearance is the capacity of a single phagocyte to inges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf536c37d1e541e9d4c5af6a910f6841
https://doi.org/10.1038/nature10340
https://doi.org/10.1038/nature10340
Autor:
Annie-Carole Tosello-Trampont, Dan R. Littman, Yuelei Shen, Amanda K. Duley, Timothy P. Bender, Ann Sutherland, Kodi S. Ravichandran, Paul C. Trampont
Publikováno v:
Nature immunology
Pre-TCR signaling is essential for the passage of thymocytes through the β-selection checkpoint. Ravichandran and co-workers find that CXCR4 acts as a costimulator for the pre-TCR and is needed for optimal progression through β-selection. Passage t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f43ce8ab0915386ff447be63f93adf
http://europepmc.org/articles/PMC2808461
http://europepmc.org/articles/PMC2808461
Publikováno v:
Cell Reports, Vol 10, Iss 5, p 840 (2015)
Cell Reports, Vol 10, Iss 3, Pp 307-316 (2015)
Cell Reports, Vol 10, Iss 3, Pp 307-316 (2015)
SummaryCancer develops after the acquisition of a collection of mutations that together create the cancer phenotype. How collections of mutations work together within a cell and whether there is selection for certain combinations of mutations are not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d239c4c5eac9c7decbed58c2c91985ff
http://www.sciencedirect.com/science/article/pii/S221112471500073X
http://www.sciencedirect.com/science/article/pii/S221112471500073X