Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Paul C. Tirrell"'
Autor:
Michael W. Greene, David E. Blask, Erin M. Dauchy, Christine M. Burrington, Potjana Jitawatanarat, Darin T. Lynch, Steven S. Wu, Paul C. Tirrell, Robert T. Dauchy, Jinghai Wu
Regulation of diurnal and circadian rhythms and cell proliferation are coupled in all mammals, including humans. However, the molecular mechanisms by which diurnal and circadian rhythms regulate cell proliferation are relatively poorly understood. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd301fbe7bd1536be5585a6ac85863e5
https://doi.org/10.1158/0008-5472.c.6503115.v1
https://doi.org/10.1158/0008-5472.c.6503115.v1
Autor:
Michael W. Greene, David E. Blask, Erin M. Dauchy, Christine M. Burrington, Potjana Jitawatanarat, Darin T. Lynch, Steven S. Wu, Paul C. Tirrell, Robert T. Dauchy, Jinghai Wu
Supplementary Figure 1 from Light at Night Activates IGF-1R/PDK1 Signaling and Accelerates Tumor Growth in Human Breast Cancer Xenografts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3464e865a622ad7bff98f03b7b10ca59
https://doi.org/10.1158/0008-5472.22390992.v1
https://doi.org/10.1158/0008-5472.22390992.v1
Autor:
Michael W Greene, Christine M Burrington, Darin T Lynch, Samantha K Davenport, Andrew K Johnson, Melissa J Horsman, Saleem Chowdhry, Jian Zhang, Janet D Sparks, Paul C Tirrell
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85848 (2014)
Steatosis, oxidative stress, and apoptosis underlie the development of nonalcoholic steatohepatitis (NASH). Protein kinase C delta (PKCδ) has been implicated in fatty liver disease and is activated in the methionine and choline-deficient (MCD) diet
Externí odkaz:
https://doaj.org/article/6daa2d05b7dd4516b00fc6449160a980
Autor:
Darin T. Lynch, Michael W. Greene, David E. Blask, Brian A. Reis, Melissa J. Horsman, Erin A. Gillaspie, Paul C. Tirrell, Christine M. Burrington, Ann Marie O'Neill, Robert T. Dauchy
Publikováno v:
Nutrition and cancer. 70(2)
The association between a Western Diet and colon cancer suggests that dietary factors and/or obesity may contribute to cancer progression. Our objective was to develop a new animal model of obesity and the associated pathophysiology to investigate hu
Autor:
Darin T. Lynch, Erin M. Dauchy, Steven S. Wu, David E. Blask, Michael W. Greene, Potjana Jitawatanarat, Christine M. Burrington, Paul C. Tirrell, Jinghai Wu, Robert T. Dauchy
Publikováno v:
Cancer Research. 71:2622-2631
Regulation of diurnal and circadian rhythms and cell proliferation are coupled in all mammals, including humans. However, the molecular mechanisms by which diurnal and circadian rhythms regulate cell proliferation are relatively poorly understood. In
Autor:
Robert T, Dauchy, Erin M, Dauchy, Robert P, Tirrell, Cody R, Hill, Leslie K, Davidson, Michael W, Greene, Paul C, Tirrell, Jinghai, Wu, Leonard A, Sauer, David E, Blask
Publikováno v:
Comparative medicine. 60(5)
Dark-phase light contamination can significantly disrupt chronobiologic rhythms, thereby potentially altering the endocrine physiology and metabolism of experimental animals and influencing the outcome of scientific investigations. We sought to deter
Autor:
David E. Blask, Erin M. Dauchy, Michael W. Greene, Robert P Tirrell, Leslie K. Davidson, Leonard A. Sauer, Paul C. Tirrell, Cody R Hill, Robert T. Dauchy
Publikováno v:
Journal of pineal research. 47(1)
Melatonin provides a circadian signal that regulates linoleic acid (LA)-dependent tumor growth. In rodent and human cancer xenografts of epithelial origin in vivo, melatonin suppresses the growth-stimulatory effects of linoleic acid (LA) by blocking
Autor:
Robert T, Dauchy, Erin M, Dauchy, Leslie K, Davidson, Jean A, Krause, Darin T, Lynch, Paul C, Tirrell, Robert P, Tirrell, Leonard A, Sauer, Peter, Van der Riet, David E, Blask
Publikováno v:
Comparative medicine. 57(4)
Melatonin and eicosapentaenoic and 10t,12c-conjugated linoleic acids suppress the growth-stimulating effects of linoleic acid (LA) and its metabolism to the mitogenic agent 13-(S)-hydroxyoctadecadienoic acid (13-(S)-HODE) in established rodent tumors
Autor:
Andrew Johnson, Michael W. Greene, Jian Zhang, Paul C. Tirrell, Janet D. Sparks, Darin T. Lynch, Samantha K. Davenport, Saleem Chowdhry, Melissa J. Horsman, Christine M. Burrington
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e85848 (2014)
PLoS ONE, Vol 9, Iss 1, p e85848 (2014)
Steatosis, oxidative stress, and apoptosis underlie the development of nonalcoholic steatohepatitis (NASH). Protein kinase C delta (PKCδ) has been implicated in fatty liver disease and is activated in the methionine and choline-deficient (MCD) diet
Autor:
Steven S. Wu, Erin M. Dauchy, Michael W. Greene, David E. Blask, Robert T. Dauchy, Jinghai Wu, Paul C. Tirrell
Publikováno v:
Cancer Research. 70:1047-1047
The circadian system and the cell cycle are two global regulatory systems in animals and humans. Previous studies have shown that disruption of either the circadian system or the cell cycle increases the risk of cancer in humans. However, the molecul