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of 4
pro vyhledávání: '"Paul C. Rosen"'
Autor:
Dorothy Koveal, Paul C. Rosen, Dylan J. Meyer, Carlos Manlio Díaz-García, Yongcheng Wang, Li-Heng Cai, Peter J. Chou, David A. Weitz, Gary Yellen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Fluorescent biosensors are important tools for studying cellular metabolism, but development and optimization are challenging. Koveal et al. present a high-throughput multiparameter screen for sensor performance, and used it to generate LiLac, a high
Externí odkaz:
https://doaj.org/article/4cfdb1ff9a2f431880f481d9dc1e1f48
Autor:
Anran Li, Dainan Mao, Aya Yoshimura, Paul C. Rosen, W. Lance Martin, Étienne Gallant, Martin Wühr, Mohammad R. Seyedsayamdost
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Low doses of antibiotics can trigger secondary metabolite biosynthesis in bacteria, but the underlying mechanisms are generally unknown. We sought to better understand this phenomenon by studying how the antibiotic trimethoprim activates the
Externí odkaz:
https://doaj.org/article/ccfb72223b13473a8b3d92fb7f6da58d
Autor:
Caroline A. Lewis, Tong Zhang, David M. Sabatini, Navdeep S. Chandel, Antonia Henne, Hans-Georg Sprenger, Andrew L. Cangelosi, Tenzin Kunchok, Jessica B. Spinelli, Julian M. Roessler, Kendall J. Condon, Jessica L. Mann, Anna M. Puszynska, Paul C. Rosen
Publikováno v:
Science. 374:1227-1237
For electrons to continuously enter and flow through the mitochondrial electron transport chain (ETC), they must ultimately land on a terminal electron acceptor (TEA), which is known to be oxygen in mammals. Paradoxically, we find that complex I and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::577ef3d14857870049b83f1312701268
https://doi.org/10.1126/science.abi7495
https://doi.org/10.1126/science.abi7495
Publikováno v:
Proc Natl Acad Sci U S A
Natural products have been an important source of therapeutic agents and chemical tools. The recent realization that many natural product biosynthetic genes are silent or sparingly expressed during standard laboratory growth has prompted efforts to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37fcbfad2e6588fe68c94e0d3343b1ac
https://pubmed.ncbi.nlm.nih.gov/34172579
https://pubmed.ncbi.nlm.nih.gov/34172579