Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Paul C. M. Winship"'
Autor:
Michael J. Tucker, Timothy J. Donohoe, Ahria Esphandiar Roushanbakhti, Wasim M. Akhtar, Yifan Liu, Daryl S. Walter, Gail L. Wrigley, Paul C. M. Winship
Publikováno v:
Angewandte Chemie International Edition. 56:14883-14887
Catalytic oxidative cyclisation reactions have been employed for the synthesis of the E and F rings of the complex natural product target pectenotoxin 4. The choice of metal catalyst (cobalt- or osmium-based) allowed for the formation of THF rings wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c7a0a05f89bf010bf36bb67dcb8e30
https://doi.org/10.1002/anie.201708278
https://doi.org/10.1002/anie.201708278
Publikováno v:
Fluorine in Heterocyclic Chemistry Volume 2 ISBN: 9783319044347
Fluorinated purines and related nucleosides exhibit a diverse range of biological activities. The presence of a single fluoro or trifluoromethyl group at the 2-, 6-, or 8-position of a purine or purine nucleoside, or combinations of multiple substitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ac643fb48ed1155d8cee8ae9032b8a
https://doi.org/10.1007/978-3-319-04435-4_9
https://doi.org/10.1007/978-3-319-04435-4_9
Autor:
Timothy J. Donohoe, Daryl S. Walter, Paul C. M. Winship, Cedric K. A. Callens, Ben S. Pilgrim
Publikováno v:
ChemInform. 42
A variety of tetrahydrofurans bearing a silyl group at the ring junction is prepared in good yields stereoselectively via a osmium-catalyzed oxidative cyclization of appropriate terminal vinyl silanes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d4fdbab707aa339062199556f00b39
https://doi.org/10.1002/chin.201107136
https://doi.org/10.1002/chin.201107136
Autor:
Paul C. M. Winship
The acid-mediated osmium-catalysed oxidative cyclisation of 1,2-diols bearing a pendent alkene has been shown to be a powerful method for the formation of cis-2,5-disubstituted tetrahydrofurans. This thesis describes the development of this methodolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::4c2e69c8c91a8a3ece0f34d352d243bf
http://ora.ox.ac.uk/objects/uuid:e4c42be0-bfea-451f-8af3-890b141423c9
http://ora.ox.ac.uk/objects/uuid:e4c42be0-bfea-451f-8af3-890b141423c9
Autor:
Cedric K. A. Callens, Daryl S. Walter, Ben S. Pilgrim, Timothy J. Donohoe, Paul C. M. Winship
Publikováno v:
Chemical communications (Cambridge, England). 46(39)
A novel osmium-catalysed oxidative cyclisation of 1,2-diols bearing a pendant vinyl silane affords THFs that contain silicon functionality at the ring junction. When the cyclisation occurs onto a vinyl benzyldimethylsilyl group, the resulting silyl g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d316b5894fb5bc5e0edf72b71bccbe5f
https://pubmed.ncbi.nlm.nih.gov/20830333
https://pubmed.ncbi.nlm.nih.gov/20830333
Publikováno v:
The Journal of organic chemistry. 74(16)
Replacing trifluoroacetic acid with a catalytic amount of Lewis acid in the osmium mediated oxidative cyclization results in higher yielding reactions that can proceed nearly an order of magnitude faster. The osmium loading can also be reduced to as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6f8334efa4411cf7a3197f4f0218f1
http://ora.ox.ac.uk/objects/uuid:eee1f945-5b84-4f4d-b634-491b02d8526d
http://ora.ox.ac.uk/objects/uuid:eee1f945-5b84-4f4d-b634-491b02d8526d
Publikováno v:
Synfacts. 2011:1048-1048
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f3b48edb8d586b30a978d5113562121
https://doi.org/10.1055/s-0030-1261142
https://doi.org/10.1055/s-0030-1261142
Autor:
Timothy J. Donohoe, Paul C. M. Winship, Ben S. Pilgrim, Daryl S. Walter, Cedric K. A. CallensAuthor to whom correspondence regarding the X-ray crystal structure should be addressed.
Publikováno v:
Chemical Communications; Oct2010, Vol. 46 Issue 39, p7310-7312, 3p