Formulation optimization of scutellarin-loaded HP-β-CD/chitosan nanoparticles using response surface methodology with Box–Behnken design

Autor: Shanshan Liu, Paul C. Ho

Publikováno v: Asian Journal of Pharmaceutical Sciences, Vol 12, Iss 4, Pp 378-385 (2017)

The aim of this paper is to investigate and optimize the preparation of scutellarin (SCU)-loaded HP-β-CD/chitosan (CS) nanoparticles (CD/CS-SCU-NPs). CD/CS-SCU-NPs were prepared by ionic cross-linking method and the process and formulation variables

Externí odkaz: https://doaj.org/article/67eaa3abdb4e472888ba906450f1d354

Correction: Glucuronidation by UGT1A1 Is the Dominant Pathway of the Metabolic Disposition of Belinostat in Liver Cancer Patients.

Autor: Ling-Zhi Wang, Jacqueline Ramírez, Winnie Yeo, Mei-Yi Michelle Chan, Win-Lwin Thuya, Jie-Ying Amelia Lau, Seow-Ching Wan, Andrea Li-Ann Wong, Ying-Kiat Zee, Robert Lim, Soo-Chin Lee, Paul C. Ho, How-Sung Lee, Anthony Chan, Sherry Ansher, Mark J. Ratain, Boon-Cher Goh

Publikováno v: PLoS ONE, Vol 9, Iss 1 (2014)

Externí odkaz: https://doaj.org/article/8a7ac3ddbc384872814137a589a51312

Dried Blood Spots as Matrix for Evaluation of Valproate Levels and the Immediate and Delayed Metabolomic Changes Induced by Single Valproate Dose Treatment

Autor: Sing Teang Kong, Hai-Shu Lin, Jianhong Ching, Huiqing Xie, Paul C. Ho

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 13; Pages: 7083

The immediate and delayed metabolic changes in rats treated with valproate (VPA), a drug used for the treatment of epilepsy, were profiled. An established approach using dried blood spots (DBS) as sample matrices for gas chromatography/mass spectrome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bea85625edc29095fe9d789e5ece93

Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial

Autor: Daniel J F M Thuijs, A Pieter Kappetein, Patrick W Serruys, Friedrich-Wilhelm Mohr, Marie-Claude Morice, Michael J Mack, David R Holmes, Nick Curzen, Piroze Davierwala, Thilo Noack, Milan Milojevic, Keith D Dawkins, Bruno R da Costa, Peter Jüni, Stuart J Head, Filip Casselman, Bernard de Bruyne, Evald Høj Christiansen, Juan M. Ruiz-Nodar, Paul Vermeersch, Werner Schultz, Manel Sabaté, Giulio Guagliumi, Herko Grubitzsch, Karl Stangl, Olivier Darremont, M. Bentala, Peter den Heijer, Istvan Preda, Robert Stoler, Michael J. Mack, Tamás Szerafin, John K. Buckner, Myles S. Guber, Niels Verberkmoes, Ferdi Akca, Ted Feldman, Friedhelm Beyersdorf, Benny Drieghe, Keith Oldroyd, Geoff Berg, Anders Jeppsson, Kimberly Barber, Kevin Wolschleger, John Heiser, Pim van der Harst, Massimo A. Mariani, Hermann Reichenspurner, Christoffer Stark, Mika Laine, Paul C. Ho, John C. Chen, Richard Zelman, Phillip A. Horwitz, Andrzej Bochenek, Agata Krauze, Christina Grothusen, Dariusz Dudek, George Heyrich, Philippe Kolh, Victor LeGrand, Pedro Coelho, Stephan Ensminger, Boris Nasseri, Richard Ingemansson, Goran Olivecrona, Javier Escaned, Reddy Guera, Sergio Berti, Alaide Chieffo, Nicholas Burke, Michael Mooney, Alvise Spolaor, Christian Hagl, Michael Näbauer, Maarten Jan Suttorp, Ronald A. Stine, Thomas McGarry, Scott Lucas, Knut Endresen, Andrew Taussig, Kevin Accola, Umberto Canosi, Ivan Horvath, Louis Cannon, John D. Talbott, Chris W. Akins, Robert Kramer, Michael Aschermann, William Killinger, Inga Narbute, David R. Holmes, Francesco Burzotta, Ad Bogers, Felix Zijlstra, Helene Eltchaninoff, Jacques Berland, Giulio Stefanini, Ignacio Cruz Gonzalez, Uta Hoppe, Stefan Kiesz, Bartlomiej Gora, Anders Ahlsson, Matthias Corbascio, Thomas Bilfinger, Didier Carrie, Didier Tchétché, Karl-Eugen Hauptman, Elisabeth Stahle, Stefan James, Sigrid Sandner, Günther Laufer, Irene Lang, Adam Witkowski, Vinod Thourani, Harry Suryapranata, Simon Redwood, Charles Knight, Philip MacCarthy, Adam de Belder, Adrian Banning, Anthony Gershlick

Publikováno v: The Lancet (London), 394, 1325-1334
Lancet (UK), 394(10206), 1325-1334. Elsevier Ltd.
The Lancet (London), 394, 10206, pp. 1325-1334

Item does not contain fulltext BACKGROUND: The Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) trial was a non-inferiority trial that compared percutaneous coronary intervention (PCI) using first-generation paclitaxel-eluting stents with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da31a85919e54f4c2561b4e29279514d
https://pure.eur.nl/en/publications/e5c7ec24-50a5-48a2-9e60-0f133f68ac1b

Resveratrol for cancer therapy: Challenges and future perspectives

Autor: Boxu Ren, Zhaowu Ma, Ling-Wen Ding, Paul C. Ho, Xiaoqiang Xiang, Marabeth Xin-Yi Kwah, Lingzhi Wang, Muthu K. Shanmugam, Cuiliu Liu, Pei Shi Ong, Boon Cher Goh

Publikováno v: Cancer letters. 515

Resveratrol (3,4',5-trihydroxy-trans-stilbene) has been expected to ameliorate cancer and foster breakthroughs in cancer therapy. Despite thousands of preclinical studies on the anticancer activity of resveratrol, little progress has been made in tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc19e6011b36d7e8aa9390e6ef55405a
https://pubmed.ncbi.nlm.nih.gov/34052324