Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Paul C. Evans"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/c1f44246e5a746939080d56c3b317e80
Autor:
Hatam Naase, Leanne Harling, Emaddin Kidher, Amir Sepehripour, Bao Nguyen, Alkistis Kapelouzou, Dennis Cokkinos, George Stavridis, Gianni Angelini, Paul C. Evans, Thanos Athanasiou
Publikováno v:
Journal of Cardiothoracic Surgery, Vol 15, Iss 1, Pp 1-9 (2020)
Abstract Objectives Cardiac surgery can lead to post-operative end-organ complications secondary to activation of systemic inflammatory response. We hypothesize that surgical trauma or cardiopulmonary bypass (CPB) may initiate systemic inflammatory r
Externí odkaz:
https://doaj.org/article/2e5ca6b3ada348768ae74a590cc7d8b9
Autor:
Ingrid Gomez, Ben Ward, Celine Souilhol, Chiara Recarti, Mark Ariaans, Jessica Johnston, Amanda Burnett, Marwa Mahmoud, Le Anh Luong, Laura West, Merete Long, Sion Parry, Rachel Woods, Carl Hulston, Birke Benedikter, Chiara Niespolo, Rohit Bazaz, Sheila Francis, Endre Kiss-Toth, Marc van Zandvoort, Andreas Schober, Paul Hellewell, Paul C. Evans, Victoria Ridger
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
The role of neutrophils in the development of atherosclerosis has long been an enigma, with few neutrophils detected within the plaque. Here, the authors show that microvesicles released from neutrophils increase vascular inflammation and enhance ath
Externí odkaz:
https://doaj.org/article/56d869ba2dc54e5c8b181fd48b5df87b
Autor:
Marwa M. Mahmoud, Jovana Serbanovic-Canic, Shuang Feng, Celine Souilhol, Rouyu Xing, Sarah Hsiao, Akiko Mammoto, Jing Chen, Markus Ariaans, Sheila E. Francis, Kim Van der Heiden, Victoria Ridger, Paul C. Evans
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Blood flow influences atherosclerosis by generating wall shear stress, which alters endothelial cell (EC) physiology. Low shear stress induces dedifferentiation of EC through a process termed endothelial-to-mesenchymal transition (EndMT). Th
Externí odkaz:
https://doaj.org/article/d73073520d3c4c1ea3aaec80eeedf382
Autor:
Marwa M. Mahmoud, Jovana Serbanovic-Canic, Shuang Feng, Celine Souilhol, Rouyu Xing, Sarah Hsiao, Akiko Mammoto, Jing Chen, Markus Ariaans, Sheila E. Francis, Kim Van der Heiden, Victoria Ridger, Paul C. Evans
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/f7db960ad367409a945ce2cf81ffa49f
Autor:
Mabruka A. Alfaidi, Janet Chamberlain, Alexander Rothman, David Crossman, Maria‐Cruz Villa‐Uriol, Patrick Hadoke, Junxi Wu, Torsten Schenkel, Paul C. Evans, Sheila E. Francis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 13 (2018)
Background Hypertension is a complex condition and a common cardiovascular risk factor. Dietary docosahexaenoic acid (DHA) modulates atherosclerosis and hypertension, possibly via an inflammatory mechanism. IL‐1 (interleukin 1) has an established r
Externí odkaz:
https://doaj.org/article/26e4924d1e0a447e9174c5b62e220ede
Autor:
Luigi Yuri Di Marco, Annalena Venneri, Eszter Farkas, Paul C. Evans, Alberto Marzo, Alejandro F. Frangi
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 593-606 (2015)
Late-onset dementia is a major health concern in the ageing population. Alzheimer's disease (AD) accounts for the largest proportion (65–70%) of dementia cases in the older population.Despite considerable research effort, the pathogenesis of late-o
Externí odkaz:
https://doaj.org/article/2d99282469204e01813105f2e7d79046
Autor:
Simon Cuhlmann, Willy Gsell, Kim Van der Heiden, Josef Habib, Jordi L. Tremoleda, Magdy Khalil, Federico Turkheimer, Merlijn J. Meens, Brenda R. Kwak, Joseph Bird, Anthony P. Davenport, John Clark, Dorian Haskard, Rob Krams, Hazel Jones, Paul C. Evans
Publikováno v:
Molecular Imaging, Vol 13 (2014)
Noninvasive imaging methods are required to monitor the inflammatory content of atherosclerotic plaques. FEDAA1106 (N-(5-fluoro- 2-phenoxyphenyl)- N -(2-(2-fluoroethoxy)-5-methoxybenzyl) acetamide) is a selective ligand for TSPO-18kDa (also known as
Externí odkaz:
https://doaj.org/article/9af240ddb9254772a44d051e519cd85a
Autor:
Luke Boldock, Amanda Inzoli, Silvia Bonardelli, Sarah Hsiao, Alberto Marzo, Andrew Narracott, Julian Gunn, Gabriele Dubini, Claudio Chiastra, Ian Halliday, Paul D Morris, Paul C Evans, Perrault C M
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0314392 (2024)
[This corrects the article DOI: 10.1371/journal.pone.0271469.].
Externí odkaz:
https://doaj.org/article/15296eee7d3846aa92410ac2812df80f
Autor:
Lindsay Canham, Sam Sendac, Mannekomba R. Diagbouga, Elena Wolodimeroff, Daniela Pirri, Blanca Tardajos Ayllon, Shuang Feng, Celine Souilhol, Timothy J.A. Chico, Paul C. Evans, Jovana Serbanovic-Canic
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:547-561
Background: Hemodynamic wall shear stress (WSS) exerted on the endothelium by flowing blood determines the spatial distribution of atherosclerotic lesions. Disturbed flow (DF) with a low WSS magnitude and reversing direction promotes atherosclerosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6ab58235be8f775988d2a61e2dd75f9
https://doi.org/10.1161/atvbaha.122.318110
https://doi.org/10.1161/atvbaha.122.318110