Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Paul C. Dinh"'
Autor:
Mohammad Shahbazi, Xindi Zhang, Paul C. Dinh, Victoria A. Sanchez, Matthew R. Trendowski, Megan M. Shuey, Tessa Nguyen, Regeneron Genetics Center, Darren R. Feldman, David J. Vaughn, Chunkit Fung, Christian Kollmannsberger, Neil E. Martin, Lawrence H. Einhorn, Nancy J. Cox, Robert D. Frisina, Lois B. Travis, Mary Eileen Dolan
Publikováno v:
Cancer Medicine, Vol 12, Iss 3, Pp 2999-3012 (2023)
Abstract Purpose Deficits in speech understanding constitute one of the most severe consequences of hearing loss. Here we investigate the clinical and genetic risk factors for symmetric deterioration of speech recognition thresholds (SRT) among cance
Externí odkaz:
https://doaj.org/article/aedaa37449a4452f9310279b835a3e66
Autor:
Xindi Zhang, Matthew R. Trendowski, Emma Wilkinson, Mohammad Shahbazi, Paul C. Dinh, Megan M. Shuey, Regeneron Genetics Center, Darren R. Feldman, Robert J. Hamilton, David J. Vaughn, Chunkit Fung, Christian Kollmannsberger, Robert Huddart, Neil E. Martin, Victoria A. Sanchez, Robert D. Frisina, Lawrence H. Einhorn, Nancy J. Cox, Lois B. Travis, M. Eileen Dolan
Publikováno v:
Cancer Medicine, Vol 11, Iss 14, Pp 2801-2816 (2022)
Abstract Purpose Cisplatin is a critical component of first‐line chemotherapy for several cancers, but causes peripheral sensory neuropathy, hearing loss, and tinnitus. We aimed to identify comorbidities for cisplatin‐induced neurotoxicities amon
Externí odkaz:
https://doaj.org/article/44f25d0b9c9c44fea27f757e2ecf0dda
Publikováno v:
Cardio-Oncology, Vol 7, Iss 1, Pp 1-3 (2021)
Abstract Significantly increased risks of cardiovascular disease occur in testicular cancer survivors given cisplatin-based chemotherapy. The postulated mechanism of platinum-based chemotherapy’s vascular toxicity has been thought secondary to its
Externí odkaz:
https://doaj.org/article/5fa29a01634841a8a116166fe0ceda41
Autor:
Aurelian Bidulescu, Paul C. Dinh, Shabir Sarwary, Emily Forsyth, Maya C. Luetke, David B. King, Jiankang Liu, Sharon K. Davis, Adolfo Correa
Publikováno v:
BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Growing evidence suggests that leptin is critical for glycemic control. Impaired leptin signaling may also contribute to low adiponectin expression in obese individuals. We assessed the association of leptin and adiponectin with i
Externí odkaz:
https://doaj.org/article/8176b6c92e674bc8aa6a84dced1f4e58
Autor:
Victoria A. Sanchez, Megan M. Shuey, Paul C. Dinh, Patrick O. Monahan, Sophie D. Fosså, Howard D. Sesso, M. Eileen Dolan, Lawrence H. Einhorn, David J. Vaughn, Neil E. Martin, Darren R. Feldman, Kurt Kroenke, Chunkit Fung, Robert D. Frisina, Lois B. Travis
Publikováno v:
Journal of Clinical Oncology. 41:2211-2226
PURPOSE Cisplatin is widely used and highly ototoxic, but patient-reported functional impairment because of cisplatin-related hearing loss (HL) and tinnitus has not been comprehensively evaluated. PATIENTS AND METHODS Testicular cancer survivors (TCS
Autor:
Victoria A. Sanchez, Paul C. Dinh, Jennessa Rooker, Patrick O. Monahan, Sandra K. Althouse, Chunkit Fung, Howard D. Sesso, Lawrence H. Einhorn, M. Eileen Dolan, Robert D. Frisina, Lois B. Travis
Publikováno v:
Journal of Cancer Survivorship. 17:27-39
PURPOSE Ototoxicity is a prominent side effect of cisplatin-based chemotherapy. There are few reports, however, estimating its prevalence in well-defined cohorts and associated risk-factors. METHODS Testicular cancer (TC) survivors given first-line c
Autor:
M. Eileen Dolan, Lois B. Travis, Lawrence H. Einhorn, Sophie D. Fossa, Patrick Monahan, Shirin Ardeshir-Rouhani-Fard, Robert Huddart, Nancy J. Cox, Eric R. Gamazon, Michiaki Kubo, Taisei Mushiroda, Christian Kollmannsberger, Chunkit Fung, David J. Vaughn, Robert J. Hamilton, Darren R. Feldman, Robert D. Frisina, Paul C. Dinh, Claudia Wing, Heather E. Wheeler, Matthew R. Trendowski, Brandon Mapes, Omar El Charif
Supplementary data from Clinical and Genome-wide Analysis of Cisplatin-induced Tinnitus Implicates Novel Ototoxic Mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034c3a2bc9c14bb6ef3619c01b3cf774
https://doi.org/10.1158/1078-0432.22470240
https://doi.org/10.1158/1078-0432.22470240
Supplementary Table S1 and S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019c8c8ef65a82865ae6bb166fb591ef
https://doi.org/10.1158/1078-0432.22468260.v1
https://doi.org/10.1158/1078-0432.22468260.v1
Effective administration of traditional cytotoxic chemotherapy is often limited by off-target toxicities. This clinical dilemma is epitomized by cisplatin, a platinating agent, which has potent antineoplastic activity due to its affinity for DNA and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d02673c15d7e31a0f9fd95dd0d65825
https://doi.org/10.1158/1078-0432.c.6526878
https://doi.org/10.1158/1078-0432.c.6526878
Autor:
M. Eileen Dolan, Lois B. Travis, Lawrence H. Einhorn, Sophie D. Fossa, Patrick Monahan, Shirin Ardeshir-Rouhani-Fard, Robert Huddart, Nancy J. Cox, Eric R. Gamazon, Michiaki Kubo, Taisei Mushiroda, Christian Kollmannsberger, Chunkit Fung, David J. Vaughn, Robert J. Hamilton, Darren R. Feldman, Robert D. Frisina, Paul C. Dinh, Claudia Wing, Heather E. Wheeler, Matthew R. Trendowski, Brandon Mapes, Omar El Charif
Purpose:Cisplatin, a commonly used chemotherapeutic, results in tinnitus, the phantom perception of sound. Our purpose was to identify the clinical and genetic determinants of tinnitus among testicular cancer survivors (TCS) following cisplatin-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c57552535da8e5e53525afdbee8a6cf
https://doi.org/10.1158/1078-0432.c.6527475.v1
https://doi.org/10.1158/1078-0432.c.6527475.v1