Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Paul C. Cheng"'
Autor:
Amey Vrudhula, Lily Stern, Paul C Cheng, Piero Ricchiuto, Chathuri Daluwatte, Ronald Witteles, Jignesh Patel, David Ouyang
BackgroundRecent studies suggest that cardiac amyloidosis (CA) is significantly underdiagnosed. For rare diseases like CA, the optimal selection of cases and controls for artificial intelligence (AI) model training is unknown and can significantly im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b159cfa78f3b7851895a67d0b983e30d
https://doi.org/10.1101/2023.03.30.23287941
https://doi.org/10.1101/2023.03.30.23287941
Autor:
Gernot Schabbauer, Julia S. Brunner, Paul C. Cheng, Melanie Hofmann, S Blüml, A Lercher, Andrea Vogel, Victoria Saferding
Publikováno v:
Poster presentations.
Introduction Osteoclasts are giant, multi-nucleated cells that derive from the monocyte-macrophage linage and are regulators of bone turnover. Availability and catabolism of L-Arginine have been implicated with immune cell biology, skewing inflammato
Autor:
Birgit Niederreiter, Gernot Schabbauer, Hannah Paar, Victoria Saferding, Stephan Blüml, Julia S. Brunner, Melanie Hofmann, Andrea Vogel, Li Chen, Paul C. Cheng
Publikováno v:
New players and novel targets in inflammation.
Background Osteoclasts are multi-nucleated, bone resorbing cells that derive from the monocyte-macrophage linage. They are further known as the main effector cells for development of age-related osteoporosis and are critically involved in the pathoge
Autor:
Tim W. Sproul, Anu Cherukuri, Michael R. Chen, Paul C. Cheng, Sunil Malapati, Susan K. Pierce, Michelle L. Dykstra
Publikováno v:
Seminars in Immunology. 13:107-114
The initiation of antibody responses to foreign antigens requires that B cells receive and integrate a variety of signals through an array of cell surface receptors including the B cell antigen receptor (BCR) as well as a number of essential corecept
Publikováno v:
The Journal of Immunology. 166:3693-3701
The cross-linking of the B cell Ag receptor (BCR) leads to the initiation of a signal transduction cascade in which the earliest events involve the phosphorylation of the immunoreceptor tyrosine-based activation motifs of Igα and Igβ by the Src fam
Publikováno v:
Immunity. 14:169-179
The CD19/CD21 complex functions to significantly enhance B cell antigen receptor (BCR) signaling in response to complement-tagged antigens. Recent studies showed that following antigen binding the BCR translocates into plasma membrane lipid rafts tha
Publikováno v:
International Reviews of Immunology. 19:139-155
For mature B cells, the encounter with foreign antigen results in the selective expansion of the cells and their differentiation into antibody secreting cells or memory B cells. The response of mature B cells to antigen requires not only antigen bind
Publikováno v:
The Journal of Experimental Medicine
The B cell antigen receptor (BCR) serves both to initiate signal transduction cascades and to target antigen for processing and presentation by MHC class II molecules. How these two BCR functions are coordinated is not known. Recently, sphingolipid-
Publikováno v:
The Journal of Immunology. 162:7171-7180
Processing and presentation by Ag-specific B cells is initiated by Ag binding to the B cell Ag receptor (BCR). Cross-linking of the BCR by Ag results in a rapid targeting of the BCR and bound Ag to the MHC class II peptide loading compartment (IIPLC)
Autor:
Paul C. Cheng, Geary Wong
Publikováno v:
Bee World. 77:8-15
Modern physicians trained in allopathic medicine are usually wary of naturopathic remedies because the mechanisms of efficacy are usually unclear. Indeed, if one examines recipes from Chinese herbal medicine or some ‘home remedies,’ the active in