Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Paul C. Anderson"'
Publikováno v:
AA practice. 10(4)
Autor:
Christian Brochu, James Gillard, Michael Bös, Martin Marquis, Richard Bethell, Gulrez Fazal, George Kukolj, Michel Garneau, Timothy A. Stammers, Paul C. Anderson, Dominik Wernic, Pierre L. Beaulieu, Stephen H. Kawai, Ginette McKercher, Marc-André Poupart, Jianmin Duan, Bounkham Thavonekham, Yves Bousquet, Michael G. Cordingley
Publikováno v:
Journal of Medicinal Chemistry. 57:10130-10143
The development of interferon-free regimens for the treatment of chronic HCV infection constitutes a preferred option that is expected in the future to provide patients with improved efficacy, better tolerability, and reduced risk for emergence of dr
Publikováno v:
International Journal of Peptide and Protein Research. 48:401-410
The solution conformations of three polyhydroxymonoamide renin inhibitors which differ in the relative configuration and position of the hydroxyl groups at the P3, position were investigated by NMR spectroscopy. The NMR data are consistent with a pre
Autor:
Paul C. Anderson, Eric S. Cole, Megan G. Rooney, Jerry E. Honts, Douglas L. Chalker, Matthew E. Majerus, Ross B. Fulton, Amy L. Wentland, Douglas J. Beussman, Johanna Savage, Erica Zweifel, Mary E. Welch
Publikováno v:
Journal of Eukaryotic Microbiology. 55:245-256
We set out to find the "fenestrin" gene, a gene whose protein is associated with numerous cellular apertures, including the nuclear exchange junction in mating Tetrahymena thermophila. First we developed protocols for imaging and isolating intact nuc
Autor:
Paul C. Anderson, Li Meng
Publikováno v:
Basic Clinical Anesthesia ISBN: 9781493917365
Pulmonary aspiration and postoperative nausea and vomiting (PONV) are two critical issues in anesthesia that have received considerable attention over the past several years. Aspiration is a rare but serious complication that has the potential to res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c75d4587b173369537372f886d4a1ca8
https://doi.org/10.1007/978-1-4939-1737-2_44
https://doi.org/10.1007/978-1-4939-1737-2_44
Autor:
Bruno Simoneau, Nathalie Goudreau, Steven M. Weldon, Mireille Cartier, Marc-André Poupart, Jean Rancourt, Gerhard G. Steinmann, Pierre R. Bonneau, Roger St. George, Chan-Loi Yong, Gordon Bolger, Murray D. Bailey, Lisette Lagacé, Anne-Marie Faucher, Daniel Lamarre, Michael G. Cordingley, Roel E. Sentjens, Pierre L. Beaulieu, Diane Thibeault, Hans Narjes, Youla S. Tsantrizos, Steven R. LaPlante, Stephen H. Kawai, Paul C. Anderson, Montse Llinas-Brunet, Michael Bös, Dale R. Cameron, George Kukolj
Publikováno v:
Nature. 426:186-189
Hepatitis C virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected individuals at risk of developing significant morbidity and mortality. Current interferon-based therapies are suboptimal espec
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2677-2689
A synthetic route is devised for the synthesis of (11S)-[11-2H1]porphobilinogen 1a and of the (11R)-enantiomer 1b. Their absolute configurations and enantiomeric purity are established by degradation to a derivative of [2-2H1]glycine of known stereoc
Publikováno v:
Tetrahedron. 53:15671-15680
Two approaches to enantiopure 4-oxo- and 4-( R )-hydroxypipecolic acid derivatives from protected L-aspartic acid were developed. The first route exploits an intramolecular Michael addition on the stable enaminone 8 . Hydrogenation and concomitant de
Autor:
Paul C. Anderson, Pierre Lavallee, James Gillard, and Ingrid Guse, Tibor Bogri, Yves Bousquet, A. Abraham, Pierre L. Beaulieu, Louis Grenier
Publikováno v:
The Journal of Organic Chemistry. 61:2226-2231
Autor:
Susan Pav, Louise Pilote, Paul C. Anderson, Steven R. LaPlante, Liang Tong, Grace Jung, Daniel Lamarre
Publikováno v:
Journal of Molecular Biology. 250:211-222
The crystal structures of recombinant glycosylated human renin in complex with several polyhydroxymonoamide inhibitors have been determined at up to 1.8 A resolution. The high resolution structures permit a detailed analysis of the conformation of re