Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Paul C Evans"'
Autor:
Luke Boldock, Amanda Inzoli, Silvia Bonardelli, Sarah Hsiao, Alberto Marzo, Andrew Narracott, Julian Gunn, Gabriele Dubini, Claudio Chiastra, Ian Halliday, Paul D Morris, Paul C Evans, Perrault C M
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0271469 (2022)
AimsCoronary artery stents have profound effects on arterial function by altering fluid flow mass transport and wall shear stress. We developed a new integrated methodology to analyse the effects of stents on mass transport and shear stress to inform
Externí odkaz:
https://doaj.org/article/9963fb28a6164e4f8513ff83c019bd93
Publikováno v:
F1000Research, Vol 10 (2021)
Introduction: Endothelial cell (EC) proliferation is a fundamental determinant of vascular development and homeostasis, and contributes to cardiovascular disease by increasing vascular permeability to blood-borne lipoproteins. Rodents have been tradi
Externí odkaz:
https://doaj.org/article/e9b50c2afb394a04a60954219b401992
Autor:
Lindsay Canham, Sam Sendac, Mannekomba R. Diagbouga, Elena Wolodimeroff, Daniela Pirri, Blanca Tardajos Ayllon, Shuang Feng, Celine Souilhol, Timothy J.A. Chico, Paul C. Evans, Jovana Serbanovic-Canic
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 43:547-561
Background: Hemodynamic wall shear stress (WSS) exerted on the endothelium by flowing blood determines the spatial distribution of atherosclerotic lesions. Disturbed flow (DF) with a low WSS magnitude and reversing direction promotes atherosclerosis
Autor:
Paul C Evans, Sean M Davidson, Johann Wojta, Magnus Bäck, Sveva Bollini, Mairi Brittan, Alberico L Catapano, Bill Chaudhry, Matthijs Cluitmans, Massimiliano Gnecchi, Tomasz J Guzik, Imo Hoefer, Rosalinda Madonna, João P Monteiro, Henning Morawietz, Elena Osto, Teresa Padró, Judith C Sluimer, Carlo Gabriele Tocchetti, Kim Van der Heiden, Gemma Vilahur, Johannes Waltenberger, Christian Weber
Publikováno v:
Cardiovascular Research. 118:2754-2767
Here, we review the highlights of cardiovascular basic science published in 2021 and early 2022 on behalf of the European Society of Cardiology Council for Basic Cardiovascular Science. We begin with non-coding RNAs which have emerged as central regu
Autor:
Mabruka A. Alfaidi, Janet Chamberlain, Alexander Rothman, David Crossman, Maria‐Cruz Villa‐Uriol, Patrick Hadoke, Junxi Wu, Torsten Schenkel, Paul C. Evans, Sheila E. Francis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 13 (2018)
Background Hypertension is a complex condition and a common cardiovascular risk factor. Dietary docosahexaenoic acid (DHA) modulates atherosclerosis and hypertension, possibly via an inflammatory mechanism. IL‐1 (interleukin 1) has an established r
Externí odkaz:
https://doaj.org/article/26e4924d1e0a447e9174c5b62e220ede
Autor:
Xiuying Li, Celine Souilhol, Lindsay Canham, Xueqi Jia, Mannekomba Diagbouga, Blanca Tardajos Ayllon, Jovana Serbanovic-Canic, Paul C. Evans
Publikováno v:
Vascular Pharmacology. 150:107178
Autor:
Allan Lawrie, Elizabeth Kugler, George Bowley, Emily S. Noël, Jovana Serbanovic-Canic, Freek van Eeden, Timothy J. A. Chico, Paul C. Evans, Robert N. Wilkinson
Publikováno v:
British Journal of Pharmacology. 179:900-917
Mammalian models including non-human primates, pigs and rodents have been used extensively to study the mechanisms of cardiovascular disease. However, there is an increasing desire for alternative model systems that provide excellent scientific value
Autor:
M-Saadeh Suleiman, Paul C. Evans, Gianni D Angelini, Shameem Ladak, Alexander O Ward, Massimo Caputo, Graciela B. Sala-Newby, Mustafa Zakkar, Sarah J George
Publikováno v:
Ward, A, Sala-Newby, G, Ladak, S, Angelini, G, Caputo, M, Suleiman, M-S, Evans, P, George, S & Zakkar, M 2021, ' Nrf2-Keap-1 imbalance under acute shear stress induces inflammatory response in venous endothelial cells ', Perfusion . https://doi.org/10.1177/02676591211012571
Vascular endothelial cell stimulation is associated with the activation of different signalling pathways and transcription factors. Acute shear stress is known to induce different pro-inflammatory mediators such as IL-8. Nrf2 is activated by prolonge
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2441
Zebrafish allow unrivalled in vivo imaging of vascular development due to their optical translucency and the availability of transgenic lines which fluorescently label cells and tissues of interest. Advances in light sheet fluorescence microscopy all
Publikováno v:
Methods in Molecular Biology ISBN: 9781071620588
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c7ab57e8af510e11f4a98d10113d8ee
https://doi.org/10.1007/978-1-0716-2059-5_2
https://doi.org/10.1007/978-1-0716-2059-5_2