Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Paul C Dimayuga"'
Autor:
Peter M Mihailovic, Wai Man Lio, Romana Herscovici, Kuang-Yuh Chyu, Juliana Yano, Xiaoning Zhao, Jianchang Zhou, Bo Zhou, Michael R Freeman, Wei Yang, Prediman K Shah, Bojan Cercek, Paul C Dimayuga
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0213025 (2019)
BackgroundInflammation is an important risk factor in atherosclerosis, the underlying cause of coronary artery disease (CAD). Unresolved inflammation may result in maladaptive immune responses and lead to immune reactivity to self-antigens. We hypoth
Externí odkaz:
https://doaj.org/article/014031a96f3b47f685e1a1c71d8e3059
Autor:
Peter M Mihailovic, Wai Man Lio, Juliana Yano, Xiaoning Zhao, Jianchang Zhou, Kuang-Yuh Chyu, Prediman K Shah, Bojan Cercek, Paul C Dimayuga
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0187432 (2017)
Auto-immunity is believed to contribute to inflammation in atherosclerosis. The antimicrobial peptide LL-37, a fragment of the cathelicidin protein precursor hCAP18, was previously identified as an autoantigen in psoriasis. Given the reported link be
Externí odkaz:
https://doaj.org/article/d1cdaf5574f845f5a7c50607c214720c
Autor:
Tomoyuki Honjo, Kuang-Yuh Chyu, Paul C Dimayuga, Wai Man Lio, Juliana Yano, Portia Trinidad, Xiaoning Zhao, Jianchang Zhou, Bojan Cercek, Prediman K Shah
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0131731 (2015)
Recent studies suggest the potential involvement of CD8+ T cells in the pathogenesis of murine hypertension. We recently reported that immunization with apoB-100 related peptide, p210, modified CD8+ T cell function in angiotensin II (AngII)-infused a
Externí odkaz:
https://doaj.org/article/f64b3b290e55492693eff7776f0b2d6b
Autor:
Kuang-Yuh Chyu, Wai Man Lio, Paul C Dimayuga, Jianchang Zhou, Xiaoning Zhao, Juliana Yano, Portia Trinidad, Tomoyuki Honjo, Bojan Cercek, Prediman K Shah
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92095 (2014)
The lipid milleu exacerbates the inflammatory response in atherosclerosis but its effect on T cell mediated immune response has not been fully elucidated. We hypothesized that lipid lowering would modulate T cell mediated immune function.T cells isol
Externí odkaz:
https://doaj.org/article/ee054644e1fc4428b850d64d3357fdf7
Autor:
Kuang-Yuh Chyu, Xiaoning Zhao, Paul C Dimayuga, Jianchang Zhou, Xiaojun Li, Juliana Yano, Wai Man Lio, Lai Fan Chan, Jonathan Kirzner, Portia Trinidad, Bojan Cercek, Prediman K Shah
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30780 (2012)
Immunization of hypercholesterolemic mice with selected apoB-100 peptide antigens reduces atherosclerosis but the precise immune mediators of athero-protection remain unclear. In this study we show that immunization of apoE (-/-) mice with p210, a 20
Externí odkaz:
https://doaj.org/article/6b662011f64a44b5882fc4c8507d5b2a
Autor:
Paul C Dimayuga, Kuang-Yuh Chyu, Jonathan Kirzner, Juliana Yano, Xiaoning Zhao, Jianchang Zhou, Prediman K Shah, Bojan Cercek
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20214 (2011)
T cells modulate neointima formation after arterial injury but the specific T cell population that is activated in response to arterial injury remains unknown. The objective of the study was to identify the T cell populations that are activated and m
Externí odkaz:
https://doaj.org/article/39f00bf153354dce97f359b757c7160a
Autor:
Fernando Chernomordik, Bojan Cercek, Jianchang Zhou, Xiaoning Zhao, Nicole Wai Man Lio, Kuang-Yuh Chyu, Prediman K. Shah, Paul C. Dimayuga
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundLL-37 is the only member of the cathelicidin family of antimicrobial peptides in humans and is an autoantigen in several autoimmune diseases and in acute coronary syndrome (ACS). In this report, we profiled the specific T cell response to t
Externí odkaz:
https://doaj.org/article/05b2d9f173b040cbbb3502583f721a77
Autor:
Paul C. Dimayuga, Xiaoning Zhao, Juliana Yano, Wai Man Lio, Jianchang Zhou, Peter M. Mihailovic, Bojan Cercek, Prediman K. Shah, Kuang‐Yuh Chyu
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 7 (2017)
BackgroundT cells are found in atherosclerotic plaques, with evidence supporting a potential role for CD8+ T cells in atherogenesis. Prior studies provide evidence of low‐density lipoprotein and apoB‐100 reactive T cells, yet specific epitopes re
Externí odkaz:
https://doaj.org/article/d61ef3d4a72e424986bc7fa385e4da06
Autor:
Kuang-Yuh Chyu, Xiaoning Zhao, Jianchang Zhou, Paul C. Dimayuga, Nicole W.M. Lio, Bojan Cercek, Noah T. Trac, Eun Ji Chung, Prediman K. Shah
Publikováno v:
JCI Insight. 7
Active immunization with the apolipoprotein B-100 (ApoB-100) peptide P210 reduces experimental atherosclerosis. To advance this immunization strategy to future clinical testing, we explored the possibility of delivering P210 as an antigen using nanop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f180510fa738cf6bd0f1c9860291fc
https://doi.org/10.1172/jci.insight.149741
https://doi.org/10.1172/jci.insight.149741
Autor:
Xiaoning Zhao, Jianchang Zhou, Kuang-yuh Chyu, Wai Man Lio, Paul C Dimayuga, Bojan Cercek, Noah Trac, Eun Ji Chung, Prediman K Shah
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Background: The use of nanoparticles for efficient delivery of therapeutic modalities in humans is rapidly increasing. We have previously reported that a nanovaccine consisting of apoB-100 peptide P210 complexed with amphiphilic micelles (P210-PAM) s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9ffb8e4b868021fbe1e53db5f30345b
https://doi.org/10.1161/atvb.42.suppl_1.510
https://doi.org/10.1161/atvb.42.suppl_1.510