Výsledky vyhledávání - "Paul C, Timm"

Treatment with the novel TAAR1 agonist ulotaront is associated with reductions in quantitative polysomnographic REM sleep without atonia in healthy human subjects: Results of a post-hoc analysis

Autor: John C, Feemster, Sarah M, Westerland, Thomas R, Gossard, Tyler A, Steele, Paul C, Timm, Jack T, Jagielski, Emma, Strainis, Stuart J, McCarter, Seth C, Hopkins, Kenneth S, Koblan, Erik K, St Louis

Publikováno v: Sleep Medicine. 101:578-586

Isolated REM sleep behavior disorder (RBD) is a potentially injurious parasomnia lacking an established treatment. Ulotaront is a trace amine-associated receptor 1 (TAAR1) agonist with 5-HTYoung healthy adult men (ages 19-35) were randomized to doubl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee90d28ca40ff3d4315f5d8db9e067ac
https://doi.org/10.1016/j.sleep.2022.11.022

Zobrazit plný text záznamu

The Accuracy and Reliability of Sleep Staging and Sleep Biomarkers in Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder

Autor: Daniel J Levendowski, Thomas C Neylan, Joyce K Lee-Iannotti, Paul C Timm, Cyrus Guevarra, Elise Angel, David Shprecher, Gandis Mazeika, Christine M Walsh, Bradley F Boeve, Erik K St Louis

Publikováno v: Nature and Science of Sleep.

Daniel J Levendowski,1 Thomas C Neylan,2 Joyce K Lee-Iannotti,3 Paul C Timm,4 Cyrus Guevarra,3 Elise Angel,1 David Shprecher,5 Gandis Mazeika,1 Christine M Walsh,6 Bradley F Boeve,4 Erik K St Louis4 1Sleep and Respiratory Research, Advanced Brain Mon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42832899ad12aebf8ede53283ef1bc6f
https://www.dovepress.com/the-accuracy-and-reliability-of-sleep-staging-and-sleep-biomarkers-in--peer-reviewed-fulltext-article-NSS

Zobrazit plný text záznamu

QT prolongation in patients with index evaluation for seizure or epilepsy is predictive of all-cause mortality

Autor: Erik K. St. Louis, Paul C. Timm, Jay Mandrekar, Jiang Xie, Rabe E. Alhurani, Joseph A. Gottwald, C. Anwar A. Chahal, Janet E. Olson, Prabin Thapa, Michael J. Ackerman, Virend K. Somers, Peter A. Brady, Elson L. So

Publikováno v: Heart Rhythm. 19:578-584

Refractory epilepsy confers a considerable lifetime risk of sudden unexplained death in epilepsy (SUDEP). Mechanisms may overlap with sudden cardiac death (SCD), particularly regarding QTc prolongation. Guidelines in the United States do not mandate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2bfbfb211034ae74a466ec3508e40aa
https://doi.org/10.1016/j.hrthm.2021.11.013

Zobrazit plný text záznamu

Non-REM sleep with hypertonia in Parkinsonian Spectrum Disorders: A pilot investigation

Autor: Daniel J. Levendowski, Christine M. Walsh, Bradley F. Boeve, Debby Tsuang, Joanne M. Hamilton, David Salat, Chris Berka, Joyce K. Lee-Iannotti, David Shprecher, Philip R. Westbrook, Gandis Mazeika, Leslie Yack, Sarah Payne, Paul C. Timm, Thomas C. Neylan, Erik K. St. Louis

Publikováno v: Sleep medicine. 100

From an ongoing multicenter effort toward differentiation of Parkinsonian spectrum disorders (PSD) from other types of neurodegenerative disorders, the sleep biomarker non-rapid-eye-movement sleep with hypertonia (NRH) emerged.This study included in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb61f3b8642f411ac7e8c22e168c2ee8
https://pubmed.ncbi.nlm.nih.gov/36274383

Zobrazit plný text záznamu

Multisite validation of a simple electronic health record algorithm for identifying diagnosed obstructive sleep apnea

Autor: Stephen F. Derose, Allan I. Pack, Timothy I. Morgenthaler, John C. Feemster, Kenneth M. Borthwick, Thomas R. Gossard, Beth A. Malow, Janet D. Robishaw, Maged Gendy, Phyllis C. Zee, Olivia J. Veatch, Luke N. Teigen, Brendan T. Keenan, Paul C. Timm, Laura Sirikulvadhana, Frances M. Pack, H. Lester Kirchner, Vicki A. Davenport

Publikováno v: Journal of Clinical Sleep Medicine. 16:175-183

We examined the performance of a simple algorithm to accurately distinguish cases of diagnosed obstructive sleep apnea (OSA) and noncases using the electronic health record (EHR) across six health systems in the United States.Retrospective analysis o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3049d635c91990e75b12a0a33ae75ab7
https://doi.org/10.5664/jcsm.8160

Zobrazit plný text záznamu

Patient Values and Preferences Regarding Prognostic Counseling in Isolated REM Sleep Behavior Disorder

Autor: Thomas R Gossard, Luke N Teigen, Seeley Yoo, Paul C Timm, Jack Jagielski, Noor Bibi, John C Feemster, Tyler Steele, Diego Z Carvalho, Mithri R Junna, Melissa C Lipford, Maja Tippmann Peikert, Laurene LeClair-Visonneau, Stuart J McCarter, Bradley F Boeve, Michael H Silber, Jessica Hirsch, Richard R Sharp, Erik K St. Louis

Publikováno v: Sleep.

Study Objectives Isolated REM sleep behavior disorder (iRBD) carries a high lifetime risk for phenoconversion to a defined neurodegenerative disease (NDD) including Parkinson disease, dementia with Lewy bodies, and multiple system atrophy. We aimed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::207cf65fc7e4ffe579f8583d3e66cff7
https://pubmed.ncbi.nlm.nih.gov/36259668

Zobrazit plný text záznamu

REM sleep atonia loss distinguishes synucleinopathy in older adults with cognitive impairment

Autor: Paul C. Timm, Stuart J. McCarter, Michael H. Silber, Erik K. St. Louis, Prashanthi Vemuri, David J. Sandness, Allison R. McCarter, Mary M. Machulda, Rodolfo Savica, Kejal Kantarci, Grace M. Tabatabai, Katie Johnson, Michelle M. Mielke, Bradley F. Boeve, Ho Yann Jong

Publikováno v: Neurology. 94:e15-e29

ObjectiveTo determine whether quantitative polysomnographic REM sleep without atonia (RSWA) distinguishes between cognitive impairment phenotypes.BackgroundNeurodegenerative cognitive impairment in older adults predominantly correlates with tauopathy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce83eaffc3a3707dae40eb0bb173dc0a
https://doi.org/10.1212/wnl.0000000000008694

Zobrazit plný text záznamu

Objective sleep profile in LGI1/CASPR2 autoimmunity

Autor: Michelle F Devine, John C Feemster, Elizabeth A Lieske, Stuart J McCarter, David J Sandness, Tyler Steele, Paul C Timm, Jay Mandrekar, Bradley F Boeve, Michael H Silber, Divyanshu Dubey, Andrew McKeon, Erik K St. Louis

Publikováno v: Sleep

Study Objectives Rapid eye movement (REM) sleep behavior disorder (RBD) and other sleep disturbances are frequent in leucine-rich, glioma inactivated protein 1-IgG (LGI1) and contactin-associated protein 2-IgG (CASPR2) autoimmunity, yet polysomnograp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812b0af126c9d22fa3c2dc5baa232dfd
https://doi.org/10.1093/sleep/zsab297

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání