Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Paul C, Lambert"'
Autor:
Chris Gale, Li Wei, Adam Timmis, Michael D Peake, Lucy Elliss-Brookes, Peter Ludman, Alison Fielding, David Adlam, Francis Murgatroyd, Clive Weston, Theresa McDonagh, Lizz Paley, Alistair Ring, Charlotte Manisty, Mike Hawkins, Raoul Reulen, Abbas Khushnood, Sally Vernon, John Deanfield, Nadeem Fazal, Jem Rashbass, Andrew Goodwin, Chengsheng Ju, Sarah Slater, Brian Shand, Mark De Belder, Paul Lambert, Catherine A Welch, Andrew Harrison, Michael Sweeting, Jennifer Lai, Mick Peake, Paul C Lambert, Mark de Belder, Paul Charlton, Alexander Lyon, Sarah Darby, Freya Tyrer, Mark Rutherford, Aderonke Temilade Abiodun, Pinkie Chambers, Kai Keen Shiu, Sally Jeans, Andy Deutsch, James Chal, Akosua Donkor, Anil Gunesh
Publikováno v:
BMJ Oncology, Vol 3, Iss 1 (2024)
Objective Fluoropyrimidine chemotherapy is a first-line treatment for many gastrointestinal (GI) cancers, however, cardiotoxicity concerns may limit administration in patients with pre-existing cardiovascular disease (CVD). This study investigated th
Externí odkaz:
https://doaj.org/article/657e4062dae14dc1813041064ef13e88
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Purpose This study introduces a novel method for estimating the variance of life expectancy since diagnosis (LEC) and loss in life expectancy (LLE) for cancer patients within a relative survival framework in situations where life tables base
Externí odkaz:
https://doaj.org/article/43f608764c6547d483c57675dff4a99f
Autor:
Anna L.V. Johansson, Simon M. Kønig, Siri Larønningen, Gerda Engholm, Niels Kroman, Karri Seppä, Nea Malila, Bjarni Á. Steig, Eva Maria Gudmundsdóttir, Elínborg J. Ólafsdóttir, Frida E. Lundberg, Therese M.-L. Andersson, Paul C. Lambert, Mats Lambe, David Pettersson, Bjarte Aagnes, Søren Friis, Hans Storm
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background: Since the early 2000s, overall and site-specific cancer survival have improved substantially in the Nordic countries. We evaluated whether the improvements have been similar across countries, major cancer types, and age groups. Material
Externí odkaz:
https://doaj.org/article/1d2bd210e5194925b1a7ab5d106cf7d2
Publikováno v:
Population Health Metrics, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Background Life expectancy is a simple measure of assessing health differences between two or more populations but current life expectancy calculations are not reliable for small populations. A potential solution to this is to borrow strengt
Externí odkaz:
https://doaj.org/article/acf23b62c70b4820ad78b9c7e97f0f71
Autor:
Marlous Hall, Lesley Smith, Jianhua Wu, Chris Hayward, Jonathan A Batty, Paul C Lambert, Harry Hemingway, Chris P Gale
Publikováno v:
PLoS Medicine, Vol 21, Iss 2, p e1004343 (2024)
BackgroundThe occurrence of a range of health outcomes following myocardial infarction (MI) is unknown. Therefore, this study aimed to determine the long-term risk of major health outcomes following MI and generate sociodemographic stratified risk ch
Externí odkaz:
https://doaj.org/article/0c117472d1d2425cbc4edaddf00ea845
Autor:
Nikolaos Skourlis, Michael J. Crowther, Therese M‑L. Andersson, Donghao Lu, Mats Lambe, Paul C. Lambert
Publikováno v:
BMC Medical Research Methodology, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Multi-state models are used to study several clinically meaningful research questions. Depending on the research question of interest and the information contained in the data, different multi-state structures and modelling choice
Externí odkaz:
https://doaj.org/article/e0e3444480f44d5c93d2f34882f2fb1f
Autor:
Nurgul Batyrbekova, Hannah Bower, Paul W. Dickman, Anna Ravn Landtblom, Malin Hultcrantz, Robert Szulkin, Paul C. Lambert, Therese M-L. Andersson
Publikováno v:
BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background There are situations when we need to model multiple time-scales in survival analysis. A usual approach in this setting would involve fitting Cox or Poisson models to a time-split dataset. However, this leads to large datasets and
Externí odkaz:
https://doaj.org/article/54b32c2833434df191097c4605e3da19
Publikováno v:
BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background When interested in a time-to-event outcome, competing events that prevent the occurrence of the event of interest may be present. In the presence of competing events, various estimands have been suggested for defining the causal e
Externí odkaz:
https://doaj.org/article/0802e5aa161b4a10964362deed94faff
Publikováno v:
BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background A lack of available data and statistical code being published alongside journal articles provides a significant barrier to open scientific discourse, and reproducibility of research. Information governance restrictions inhibit the
Externí odkaz:
https://doaj.org/article/000f1a1f9cde427d9e34f035f6cbb0d5
Publikováno v:
BMC Medical Research Methodology, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background A relative survival approach is often used in population-based cancer studies, where other cause (or expected) mortality is assumed to be the same as the mortality in the general population, given a specific covariate pattern. The
Externí odkaz:
https://doaj.org/article/02f26bc2d0e24550bd522e89f368979c