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Akademický článek

Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin

Autor: Madhusudan Rajendran, Raffael Nachbagauer, Megan E. Ermler, Paul Bunduc, Fatima Amanat, Ruvim Izikson, Manon Cox, Peter Palese, Maryna Eichelberger, Florian Krammer

Publikováno v: mBio, Vol 8, Iss 2 (2017)

ABSTRACT Antibody responses to influenza virus hemagglutinin provide protection against infection and are well studied. Less is known about the human antibody responses to the second surface glycoprotein, neuraminidase. Here, we assessed human antibo

Externí odkaz: https://doaj.org/article/7c9329d833a84c95bbc4fca196652c5c

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Enhancement of Zika virus pathogenesis by preexisting antiflavivirus immunity

Autor: Adolfo García-Sastre, Justin J. Frere, Florian Krammer, Domenico Tortorella, Jean K. Lim, Paul Bunduc, Gregory A. Foster, James Duehr, Julia A. Brown, Susan L. Stramer, Shashank Tripathi, David E. Krysztof, Raffael Nachbagauer, Susana V. Bardina

Publikováno v: Science (New York, N.Y.). 356(6334)

One antibody for all and all antibodies for one Antibodies against related flavi-viruses such as dengue (DENV) and West Nile (WNV) can cross-react with Zika virus (ZIKV) and could thereby increase disease severity. Bardina et al. tested whether DENV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bbde8f90c658d967b0798047e7396f
https://pubmed.ncbi.nlm.nih.gov/28514683

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