Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Paul Brotherton"'
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Akademický článek
Mitochondrial genome sequencing in Mesolithic North East Europe Unearths a new sub-clade within the broadly distributed human haplogroup C1.
Autor: Clio Der Sarkissian, Paul Brotherton, Oleg Balanovsky, Jennifer E L Templeton, Bastien Llamas, Julien Soubrier, Vyacheslav Moiseyev, Valery Khartanovich, Alan Cooper, Wolfgang Haak, Genographic Consortium
Publikováno v: PLoS ONE, Vol 9, Iss 2, p e87612 (2014)
The human mitochondrial haplogroup C1 has a broad global distribution but is extremely rare in Europe today. Recent ancient DNA evidence has demonstrated its presence in European Mesolithic individuals. Three individuals from the 7,500 year old Mesol
Externí odkaz: https://doaj.org/article/26760f2811964bf0babc7b9307fc2acf
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3
Late Pleistocene Australian Marsupial DNA Clarifies the Affinities of Extinct Megafaunal Kangaroos and Wallabies
Autor: Marta Kasper, Kieren J. Mitchell, Jessica L. Metcalf, Stephen M. Richards, Bastien Llamas, Aaron B. Camens, Kyle N. Armstrong, Jennifer E. L. Templeton, Alan Cooper, Vicki A. Thomson, Michael S. Y. Lee, Paul Brotherton
Publikováno v: Molecular Biology and Evolution. 32:574-584
Understanding the evolution of Australia's extinct marsupial megafauna has been hindered by a relatively incomplete fossil record and convergent or highly specialized morphology, which confound phylogenetic analyses. Further, the harsh Australian cli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36196921892c04e431fbb813b348750f
https://doi.org/10.1093/molbev/msu338
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4
Novel high-resolution characterization of ancient DNA reveals C > U-type base modification events as the sole cause of post mortem miscoding lesions
Autor: Alan Cooper, Mark A. Beaumont, Jeremy J. Austin, Ross Barnett, Paul Brotherton, Juan J. Martínez Sánchez, Phillip Endicott
Publikováno v: Nucleic Acids Research
Ancient DNA (aDNA) research has long depended on the power of PCR to amplify trace amounts of surviving genetic material from preserved specimens. While PCR permits specific loci to be targeted and amplified, in many ways it can be intrinsically unsu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e96503ce24bb071bd4f3f34c553b74
http://europepmc.org/articles/PMC2034480
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5
DNA capture and next-generation sequencing can recover whole mitochondrial genomes from highly degraded samples for human identification
Autor: Wolfgang Haak, Julien Soubrier, Paul Brotherton, Bastien Llamas, Alan Cooper, Jeremy J. Austin, Jennifer E. L. Templeton
Publikováno v: Investigative Genetics
BackgroundMitochondrial DNA (mtDNA) typing can be a useful aid for identifying people from compromised samples when nuclear DNA is too damaged, degraded or below detection thresholds for routine short tandem repeat (STR)-based analysis. Standard mtDN
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2799890d71caec749c15bb42787a5943
https://doi.org/10.1186/2041-2223-4-26
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6
Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans
Autor: Paul Brotherton, Simon Y. W. Ho, Lluis Quintana-Murci, Jonas Korlach, Harald Meller, Clio Der Sarkissian, Kurt W. Alt, Alan Cooper, Christina J. Adler, Guido Brandt, Robert Ganslmeier, Khai Luong, Stephen M. Richards, Wolfgang Haak, Jennifer E. L. Templeton, Julien Soubrier, Mark B. Van der Hoek, Mannis van Oven, Rosalie Kenyon, Veit Dresely, Susanne Friederich, Doron M. Behar
Publikováno v: Nature Communications
Nature Communications, 4. Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
instname
Digital.CSIC. Repositorio Institucional del CSIC
Brotherton, Paul et al.-- The Genographic Consortium
Haplogroup H dominates present-day Western European mitochondrial DNA variability (>40%), yet was less common (∼19%) among Early Neolithic farmers (∼5450 BC) and virtually absent in Mesoli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6cac42bc88899da4d5eb1b1de9c3b84
https://hdl.handle.net/1765/58518
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7
Genotyping human ancient mtDNA control and coding region polymorphisms with a multiplexed Single-Base-Extension assay: the singular maternal history of the Tyrolean Iceman
Autor: Jerome Brooks, Paul Brotherton, Irene Pichler, Phillip Endicott, Alan Cooper, Peter P. Pramstaller, Juan J. Sanchez, Eduard Egarter-Vigl
Publikováno v: BMC Genetics
BMC Genetics, Vol 10, Iss 1, p 29 (2009)
Background Progress in the field of human ancient DNA studies has been severely restricted due to the myriad sources of potential contamination, and because of the pronounced difficulty in identifying authentic results. Improving the robustness of hu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f6c2f04747cd9f67bf3d92f2032cec
https://pubmed.ncbi.nlm.nih.gov/19545382
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8
Preferential access to genetic information from endogenous hominin ancient DNA and accurate quantitative SNP-typing via SPEX
Autor: Juan J. Martínez Sánchez, Alan Cooper, Phillip Endicott, Paul Brotherton
Publikováno v: Nucleic Acids Research
The analysis of targeted genetic loci from ancient, forensic and clinical samples is usually built upon polymerase chain reaction (PCR)-generated sequence data. However, many studies have shown that PCR amplification from poor-quality DNA templates c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6120206bfd03b1653224fee7d473da15
http://europepmc.org/articles/PMC2811011
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