Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Paul Brito-Vargas"'
Autor:
Laura I. van Dyck, Dipal Nagda, Avner Schlessinger, Sofia B. Lizarraga, Abbie M. Maguire, Michael Schmidt, Diane Hoffman-Kim, Qing Wu, Paul Brito-Vargas, Mara H. Cowen, Liane L. Livi, Li Ma, Matthew F. Pescosolido, Qing Ouyang, Ece D. Gamsiz Uzun, Shanique Alabi, Brian C. Kavanaugh, Eric M. Morrow, Richard N. Jones
Publikováno v:
Sci Transl Med
Christianson syndrome (CS), an X-linked neurological disorder characterized by postnatal attenuation of brain growth (postnatal microcephaly), is caused by mutations in SLC9A6 (also termed NHE6), the gene encoding endosomal Na(+)/H(+) exchanger 6 (NH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb7b13f6232a78e35636cba1bfae712
https://doi.org/10.1126/scitranslmed.aaw0682
https://doi.org/10.1126/scitranslmed.aaw0682
Human neurons from Christianson syndrome iPSCs reveal allele-specific responses to rescue strategies
Autor:
Abbie M. Maguire, Qing Wu, Matthew F. Pescosolido, Michael Schmidt, Sofia B. Lizarraga, Avner Schlessinger, Eric M. Morrow, Laura I. van Dyck, Li Ma, Richard N. Jones, Ece D Gamzis Uzun, Mara H. Cowen, Paul Brito-Vargas, Dipal Nagda, Shanique Alabi, Liane L. Livi, Diane Hoffman-Kim
Human genetic disorders provide a powerful lens to understanding the human brain. Induced pluripotent stem cells (iPSC) represent an important, new resource for mechanistic studies and therapeutic development. Christianson syndrome (CS), an X-linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0155d26047d52f7cb62a62ca1eebcc
https://doi.org/10.1101/444232
https://doi.org/10.1101/444232
Autor:
Sharmina Miller-Randolph, Andrew P. Tosolini, Ryan Passino, Victor Wong, Giampietro Schiavo, Leif A. Havton, Roman J. Giger, James N. Sleigh, Amar N. Kar, Alicia L. Hawthorne, Paul Brito-Vargas, Cristina Picci, Seung Joon Lee, Jeffery L. Twiss, Deanna S. Smith, Brett Langley, John Craver, Liang Shi, Ashley L. Kalinski, Dianna E. Willis
Publikováno v:
The Journal of Cell Biology
Van Den Bosch highlights the discovery by Kalinski et al. of Miro1 as an HDAC6 substrate that regulates mitochondrial trafficking in neurons and axon regeneration.
Myelin-associated glycoprotein and chondroitin sulfate proteoglycans in the extra
Myelin-associated glycoprotein and chondroitin sulfate proteoglycans in the extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff5989a1a5873efca49b789a2a6bef1
https://pubmed.ncbi.nlm.nih.gov/31118238
https://pubmed.ncbi.nlm.nih.gov/31118238
Autor:
Paul Brito-Vargas, Beatriz Cruz, Mélanis Rivera, Jeffrey Parrilla-Carrero, Rebecca García-Sosa, Jennifer L. Barreto-Estrada, Orialis Figueroa, Alejandro Lugo
Publikováno v:
Drug and Alcohol Dependence. 100:122-127
Anabolic androgenic steroids (AAS) are often misused by adolescents and athletes. Their effects vary according to chemical structure and metabolism, route of administration, and AAS regimen. In this study, adult C57Bl/6 male mice were systemically ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0adc535b289cfeb7f455a7afc28204
https://doi.org/10.1016/j.drugalcdep.2008.09.014
https://doi.org/10.1016/j.drugalcdep.2008.09.014
Autor:
Cynthia Gomes, Jennifer Coleman, Tanuja T. Merianda, Jeffery L. Twiss, Heikki Rauvala, Hak Hee Kim, Pabitra K. Sahoo, Armin Blesch, Paul Brito-Vargas, Soonmoon Yoo
High mobility group (HMG) proteins concentrate in the nucleus, interacting with chromatin. Amphoterin is an HMG protein (HMGB1) that has been shown to have extranuclear functions and can be secreted from some cell types. Exogenous amphoterin can incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a38ae39006c58704f528a0446295237
https://europepmc.org/articles/PMC4388927/
https://europepmc.org/articles/PMC4388927/
Autor:
Jennifer L. Barreto-Estrada, Adhly Huertas, Paul Brito-Vargas, Eduardo Natal, Freddyson J Martinez
Publikováno v:
The FASEB Journal. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56b3cc4f6eac6265e07eeb56751131d7
https://doi.org/10.1096/fasebj.25.1_supplement.lb25
https://doi.org/10.1096/fasebj.25.1_supplement.lb25
Autor:
Paul Brito-Vargas, Jim R. Fadel, Amanda C. Sharko, Kris F. Kaigler, Elisabeth M. Oliver, Marlene A. Wilson, Ryan K. Butler
Exposure of rats to an odor of a predator can elicit an innate fear response. In addition, such exposure has been shown to activate limbic brain regions such as the amygdala. However, there is a paucity of data on the phenotypic characteristics of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81457a67c2a2d3a704fa340179a99936
https://europepmc.org/articles/PMC3031785/
https://europepmc.org/articles/PMC3031785/