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pro vyhledávání: '"Paul Brent Watkins"'
Autor:
Jeffrey L Woodhead, Kyunghee eYang, Scott Q Siler, Paul Brent Watkins, Kim L.R. Brouwer, Hugh A Barton, Brett A Howell
Publikováno v:
Frontiers in Pharmacology, Vol 5 (2014)
Inhibition of the bile salt export pump (BSEP) has been linked to incidence of drug-induced liver injury (DILI), presumably by the accumulation of toxic bile acids in the liver. We have previously constructed and validated a model of bile acid dispos
Externí odkaz:
https://doaj.org/article/64259af463dc478a95f0ad84590ccafa
Publikováno v:
Frontiers in Genetics, Vol 3 (2012)
Abstract The ability to identify mechanisms underlying drug-induced liver injury (DILI) in man has been hampered by the difficulty in obtaining liver tissue from patients. It has recently been proposed that whole blood toxicogenomics may provide a no
Externí odkaz:
https://doaj.org/article/cca58d85b8fa4c94888be7b09254ff9b