An undergraduate research experience in earth science education that benefits pre-service teachers and in-service earth science teachers

Autor: James R. Ebert, Glenn Dolphin, Paul Bischoff

Three cohorts of six pre-service Earth Science teachers (undergraduate majors in Earth Science Education) participated in summer research experiences focused on developing dynamic physical models of Earth processes to help middle and high school stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b2ecbdda81c4437aabce6fb8305c42

Integration Challenges of Flash Lamp Annealed LTPS for High Performance CMOS TFTs

Autor: Robert George Manley, Glenn Packard, Viraj Garg, Paul Bischoff, Karl D. Hirschman, Karthik Bhadrachalam, Adam Rosenfeld

Publikováno v: ECS Transactions. 86:57-72

The development of low-temperature polycrystalline silicon (LTPS) based on excimer laser annealing (ELA) has realized CMOS TFTs with notable electrical performance. The flat-panel display industry is searching for alternative LTPS strategies which ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199e5c64fb807af9f9252a50ea2a6f4b
https://doi.org/10.1149/08611.0057ecst

Design and synthesis of a novel series of cyanoindole derivatives as potent γ-secretase modulators

Autor: Garrett Berlond Minne, Michel Surkyn, Harrie J.M. Gijsen, Francois Paul Bischoff, Nigel Austin, Marc Mercken, Didier Berthelot, Chiara Zavattaro, Ishtiyaque Ahmad, Gregor James Macdonald, Adriana Ingrid Velter, Michel Anna Jozef De Cleyn, Deborah Dhuyvetter, Sven Franciscus Anna Van Brandt, Serge Maria Aloysius Pieters, Yves Emiel Maria Van Roosbroeck, Swapan Kumar Samanta, Herman Borghys

Publikováno v: Bioorganicmedicinal chemistry letters. 29(14)

The discovery, design and synthesis of a new series of GSMs is described. The classical imidazole heterocycle has been replaced by a cyano group attached to an indole nucleus. The exploration of this series has led to compound 26-S which combined hig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9f458af2fb6e368fbdd2185f1f9926
https://pubmed.ncbi.nlm.nih.gov/31122869

Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists

Autor: Brian Lord, Jason C. Rech, Brian Scott, Kirsten L. Morton, Nicholas I. Carruthers, Victor Contreras, Natalie A. Hawryluk, Qi Wang, Xiaohui Jiang, Francois Paul Bischoff, Michael A. Letavic, Alan D. Wickenden, Pascal Bonaventure, Hong Ao, Serge Maria Aloysius Pieters, Zachary S. Sales, Anindya Bhattacharya, Adriana Ingrid Velter

Publikováno v: ACS Medicinal Chemistry Letters. 4:419-422

The synthesis and preclinical characterization of two novel, brain penetrating P2X7 compounds will be described. Both compounds are shown to be high potency P2X7 antagonists in human, rat, and mouse cell lines and both were shown to have high brain c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c778658858962a1ac276dc8d4cd5e98
https://doi.org/10.1021/ml400040v

Synthesis and biodistribution of [11C]R107474, a new radiolabeled α2-adrenoceptor antagonist

Autor: Josée E. Leysen, Margot H. Bakker, R. P. Klok, Albert D. Windhorst, François Paul Bischoff, Ludo Edmond Josephine Kennis, L. Heylen, Jacobus D. M. Herscheid, Xavier Langlois, Mirek Jurzak, M. Van der Mey

Publikováno v: Bioorganic and Medicinal Chemistry, 14(13), 4526-4534. Elsevier Limited
Van der Mey, M, Windhorst, A D, Klok, R P, Herscheid, J D M, Kennis, L E, Bischoff, F, Bakker, M, Langlois, X, Heylen, L, Jurzak, M & Leysen, J E 2006, ' Synthesis and biodistribution of [ 11 C]R107474, a new radiolabeled α 2-adrenoceptor antagonist ', Bioorganic and Medicinal Chemistry, vol. 14, no. 13, pp. 4526-4534 . https://doi.org/10.1016/j.bmc.2006.02.029

R107474, 2-methyl-3-[2-(1,2,3,4-tetrahydrobenzo[4,5]furo[3,2-c]pyridin-2-yl)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one, was investigated using in vitro and in vivo receptor assays and proved to be a potent and relatively selective α2-adrenoceptor antago

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d905ccb0de0694155982524471fd9a46
http://www.scopus.com/inward/record.url?scp=33646569978&partnerID=8YFLogxK