Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Paul Bieniasz"'
Publikováno v:
Retrovirology, Vol 18, Iss 1, Pp 1-14 (2021)
Abstract Background A critical step in the HIV-1 replication cycle is the assembly of Gag proteins to form virions at the plasma membrane. Virion assembly and maturation are facilitated by the cellular polyanion inositol hexaphosphate (IP6), which is
Externí odkaz:
https://doaj.org/article/adf5a4becd994d749f1e79b7397feec3
Autor:
Lindsay McDonald, Helen Wise, Frauke Muecksch, Daniel Poston, Sally Mavin, Kate Templeton, Elizabeth Furrie, Claire Richardson, Jaqueline McGuire, Lisa Jarvis, Kristen Malloy, Andrew McAuley, Norah Palmateer, Elizabeth Dickson, Theodora Hatziioannou, Paul Bieniasz, Sara Jenks
Publikováno v:
Journal of Clinical Virology Plus, Vol 1, Iss 3, Pp 100028- (2021)
Background: Sero-surveillance of SARS-CoV-2 is crucial to monitoring levels of population exposure and informing public health responses, but may be influenced by variability in performance between available assays. Methods: Five commercial immunoass
Externí odkaz:
https://doaj.org/article/7ea046edca154fc285eca2157711a447
Autor:
Claire Pardieu, Raphaël Vigan, Sam J Wilson, Alessandra Calvi, Trinity Zang, Paul Bieniasz, Paul Kellam, Greg J Towers, Stuart J D Neil
Publikováno v:
PLoS Pathogens, Vol 6, Iss 4, p e1000843 (2010)
Tetherin (CD317/BST2) is an interferon-induced membrane protein that inhibits the release of diverse enveloped viral particles. Several mammalian viruses have evolved countermeasures that inactivate tetherin, with the prototype being the HIV-1 Vpu pr
Externí odkaz:
https://doaj.org/article/7113b79c74de438b86ce9fc3b3a9f26c
Autor:
Aakansha Nangarlia, Farah Fazloon Hassen, Gabriela Canziani, Praneeta Bandi, Choya Talukder, Fengwen Zhang, Douglas Krauth, Ebony Gary, David Weiner, Paul Bieniasz, Sonia Navas-Martin, Barry O'Keefe, Charles Ang, Irwin Chaiken
Host cell infection by SARS-CoV-2, similar to that by HIV-1, is driven by a conformationally metastable and highly glycosylated surface entry protein complex, and infection by these viruses has been shown to be inhibited by the mannose-specific lecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c61a5536965166d5ddafd45eff273dc
https://doi.org/10.26434/chemrxiv-2023-2ng8k
https://doi.org/10.26434/chemrxiv-2023-2ng8k
Autor:
ZIJUN WANG, Frauke Muecksch, Alice Cho, Christian Gaebler, Hans-Heinrich Hoffmann, Victor Ramos, Shuai Zong, Melissa Cipolla, Briana Johnson, Fabian Schmidt, Justin DaSilva, Eva Bednarski, Tarek Ben Tanfous, Raphael Raspe, Kaihui Yao, Yu Lee, Teresia Chen, Martina Turroja, Katrina G. Milard, Juan Dizon, Anna Kaczynska, Anna Gazumyan, Thiago Y. Oliveira, Charles M. Rice, Marina Caskey, Paul Bieniasz, Theodora Hatziioannou, Christopher O. Barnes, Michel Nussenzweig
Publikováno v:
bioRxiv : the preprint server for biology.
SummarySARS-CoV-2 infection or vaccination produces neutralizing antibody responses that contribute to better clinical outcomes. The receptor binding domain (RBD) and the N-terminal domain (NTD) of the spike trimer (S) constitute the two major neutra
Autor:
Zoe Yeoh, Jennifer Meagher, Chia-Yu Kang, Jennifer Bohn, Paul Bieniasz, Melanie Ohi, Janet Smith
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 78:a69-a69
Publikováno v:
The Journal of Immunology. 194:215.26-215.26
Human immunodeficiency virus (HIV), is a retrovirus that infects cells of the human immune system, including CD4+ T cells, macrophages and dendritic cells. Previously, two of the candidate genes identified showed a capacity to protect cells from HI
Autor:
Débora M. Portilho, Juliette Fernandez, Mathieu Ringeard, Anthony K. Machado, Aude Boulay, Martha Mayer, Michaela Müller-Trutwin, Anne-Sophie Beignon, Frank Kirchhoff, Sébastien Nisole, Nathalie J. Arhel
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2016, 14 (2), pp.355-369. ⟨10.1016/j.celrep.2015.12.039⟩
Cell Reports, 2016, 14 (2), pp.355-369. ⟨10.1016/j.celrep.2015.12.039⟩
Cell Reports, Vol 14, Iss 2, Pp 355-369 (2016)
Cell Reports, Elsevier Inc, 2016, 14 (2), pp.355-369. ⟨10.1016/j.celrep.2015.12.039⟩
Cell Reports, 2016, 14 (2), pp.355-369. ⟨10.1016/j.celrep.2015.12.039⟩
Cell Reports, Vol 14, Iss 2, Pp 355-369 (2016)
Summary During retroviral infection, viral capsids are subject to restriction by the cellular factor TRIM5α. Here, we show that dendritic cells (DCs) derived from human and non-human primate species lack efficient TRIM5α-mediated retroviral restric