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pro vyhledávání: '"Paul Bastian"'
Autor:
Kavita Bhalla, Sausan Jaber, Nanaji Nahid M., Karen Underwood, Afshin Beheshti, Ari Landon, Binny Bhandary, Paul Bastian, Andrew M. Evens, John Haley, Brian Polster, Ronald B. Gartenhaus
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-2 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://doaj.org/article/6ac761ca178346e9acb60790be568f4a
Publikováno v:
HMD Praxis der Wirtschaftsinformatik. 60:381-404
ZusammenfassungDezentrale Identitätsökosysteme bieten vielversprechende Lösungen für vielfältige Anwendungen in der Privatwirtschaft und öffentlichen Verwaltung. Die Anwendungen haben dabei sehr unterschiedliche Bedürfnisse und regulierte Umge
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Autor:
Daniel R. McNeill, David M. Wilson, Paul Bastian, Kevin G. Becker, Helen R. Russell, Peter J. McKinnon, Jennifer L. Illuzzi, Boris M. Brenerman, Fred Bunz, Robert P. Wersto
Publikováno v:
Environmental and Molecular Mutagenesis. 58:84-98
Base excision repair (BER) is the major pathway for coping with most forms of endogenous DNA damage, and defects in the process have been associated with carcinogenesis. Apurinic/apyrimidinic endonuclease 1 (APE1) is a central participant in BER, fun
Autor:
Kevin G. Becker, Michele K. Evans, Paul Bastian, Yoonseo Kim, Yongqing Zhang, Douglas F. Dluzen, Nicole Noren Hooten, Elin Lehrmann
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Oxidative stress is thought to contribute to aging and age-related diseases, such as cardiovascular and neurodegenerative diseases, and is a risk factor for systemic arterial hypertension. Previously, we reported differential mRNA and microRNA (miRNA
Autor:
Paul Bastian, Supriyo De, Anne Tseng, Soumita Ghosh, Sanjay Kumar Bharti, Teruaki Iyama, Karsten Scheibye-Alsing, Evandro Fei Fang, Ilya G. Goldberg, Robert M. Brosh, Myriam Gorospe, Krisztina Marosi, Robert W. Maul, Henok Kassahun, Mark P. Mattson, Martin Borch Jensen, Lynn Froetscher, Morten Scheibye-Knudsen, Hilde Nilsen, Vilhelm A. Bohr, David Mark Eckley, David M. Wilson
Publikováno v:
Proceedings of the National Academy of Sciences. 113:12502-12507
Cockayne syndrome is a neurodegenerative accelerated aging disorder caused by mutations in the CSA or CSB genes. Although the pathogenesis of Cockayne syndrome has remained elusive, recent work implicates mitochondrial dysfunction in the disease prog
Autor:
Amaresh C. Panda, David Ross, Andrea Di Francesco, David Siegel, Kotb Abdelmohsen, Alberto Diaz-Ruiz, Michel Bernier, Ignacio Navas-Enamorado, Clara Di Germanio, Myriam Gorospe, Phu Huynh, Rafael de Cabo, Jennifer L. Martindale, Paul Bastian, Elin Lehrmann, Robert Peaden
Publikováno v:
Free Radical Biology and Medicine. 99:225-233
NAD(P)H: quinone oxidoreductase (NQO1) is essential for cell defense against reactive oxidative species, cancer, and metabolic stress. Recently, NQO1 was found in ribonucleoprotein (RNP) complexes, but NQO1-interacting mRNAs and the functional impact
Autor:
Christopher E. Coletta, Kevin G. Becker, D. Mark Eckley, Nikita Orlov, Ilya G. Goldberg, Paul Bastian, Elin Lehrmann, Yonqing Zhang, Mark A. Wilson, Wendy B. Iser
In this study, we describe a morphological biomarker that detects multiple discrete subpopulations (or "age-states") at several chronological ages in a population of nematodes (Caenorhabditis elegans). We determined the frequencies of three healthy a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b897810821b941a1b6f8b065cd387b
https://europepmc.org/articles/PMC6001903/
https://europepmc.org/articles/PMC6001903/
Autor:
Kavita Bhalla, Nanaji Nahid M., Ari Landon, Andrew M. Evens, Paul Bastian, Karen Underwood, John D. Haley, Sausan M. Jaber, Binny Bhandary, Brian M. Polster, Afshin Beheshti, Ronald B. Gartenhaus
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Published molecular profiling studies in patients with lymphoma suggested the influence of hypoxia inducible factor-1 alpha (HIF1α) targets in prognosis of DLBCL. Yet, the role of hypoxia in hematological malignancies remains unclear. We observed th
Autor:
Elizabeth Kiernan, Paul Bastian, Liza Dorfman, Ioannis N. Anastopoulos, Brad Wubbenhorst, Clemens Krepler, Vito Rebecca, Meenhard Herlyn, Katherine Nathanson
Publikováno v:
Cancer Research. 79:1682-1682
Large discovery sequencing analyses conducted by our group and others enabled classification of melanomas into major and minor subtypes, helping to elucidate the role and diversity of activating mutations within the MAPK pathway. We sequenced 482 mel