Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Paul Balbo"'
Autor:
Atli, Thorarensen, Paul, Balbo, Mary E, Banker, Robert M, Czerwinski, Max, Kuhn, Tristan S, Maurer, Jean-Baptiste, Telliez, Fabien, Vincent, Arthur J, Wittwer
Publikováno v:
Bioorganicmedicinal chemistry. 29
Recent years have seen a resurgence in drug discovery efforts aimed at the identification of covalent inhibitors which has led to an explosion of literature reports in this area and most importantly new approved therapies. These reports and breakthro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56f2f6c0d2c58d96767fd02cd0a3598e
https://pubmed.ncbi.nlm.nih.gov/33285410
https://pubmed.ncbi.nlm.nih.gov/33285410
Autor:
Robert M. Czerwinski, Mary Ellen Banker, Paul Balbo, Atli Thorarensen, Jean-Baptiste Telliez, Max Kuhn, Arthur J. Wittwer, Tristan S. Maurer, Fabien Vincent
Publikováno v:
Bioorganic & Medicinal Chemistry. 29:115865
Recent years have seen a resurgence in drug discovery efforts aimed at the identification of covalent inhibitors which has led to an explosion of literature reports in this area and most importantly new approved therapies. These reports and breakthro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77b5c935f3698be21b602905c739ef31
https://doi.org/10.1016/j.bmc.2020.115865
https://doi.org/10.1016/j.bmc.2020.115865
Autor:
Li Xing, Jane M. Withka, Guoyun Bai, Mark E. Bunnage, Bruce Allen Lefker, Leslie Anthony Dakin, Sheng Tan, Shenping Liu, Mary Ellen Banker, Parag Sahasrabudhe, Ariamala Gopalsamy, Atli Thorarensen, Hua Xu, Jennifer A. Young, Joerg Bussenius, Boris A. Chrunyk, Jinshan M. Chen, Kieran F. Geoghegan, Stephen W. Wright, Suman Shanker, Jeremy T. Starr, Paul Balbo, Xiayang Qiu, Zuojun Guo, Wei Li, Lyn H. Jones, Fabien Vincent, Lise R. Hoth
Publikováno v:
Scientific Reports
Interleukin-17A (IL-17A) is a principal driver of multiple inflammatory and immune disorders. Antibodies that neutralize IL-17A or its receptor (IL-17RA) deliver efficacy in autoimmune diseases, but no small-molecule IL-17A antagonists have yet progr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d84fd35679a6248c177be87226d5378
Publikováno v:
Biochemistry. 47:6859-6869
In yeast, the mRNA processing enzyme poly(A) polymerase is tethered to the much larger 3'-end processing complex via Fip1, a 36 kDa protein of unknown structure. We report the 2.6 A crystal structure of yeast poly(A) polymerase in complex with a pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8c4495bd416a8e52e26bbe301715ff
https://doi.org/10.1021/bi800204k
https://doi.org/10.1021/bi800204k