Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paul B. W. Ten Kortenaar"'
A two-step sulfurization for efficient solution-phase synthesis of phosphorothioate oligonucleotides
Autor:
Martijn C. de Koning, Amar B. T. Ghisaidoobe, Dmitri V. Filippov, Herman S. Overkleeft, Gijs A. van der Marel, Paul B. W. Ten Kortenaar, Howard I. Duynstee
Publikováno v:
Tetrahedron Letters. 49:3129-3132
A solution-phase approach for the synthesis of phosphorothioate oligonucleotides that circumvents the use of chromatographic purifications of protected phosphorothioate intermediates was developed. Implementation of a two-step sulfurization protocol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bea4443f881ac664b60fb358272f3aa0
https://doi.org/10.1016/j.tetlet.2008.03.025
https://doi.org/10.1016/j.tetlet.2008.03.025
Autor:
Amar B. T. Ghisaidoobe, and Dmitri V. Filippov, Howard I. Duynstee, Paul B. W. Ten Kortenaar, Martijn C. de Koning, Gijs A. van der Marel
Publikováno v:
Organic Process Research & Development. 10:1238-1245
A solution-phase synthesis protocol amenable to scale-up was developed for the preparation of oligonucleotides employing phosphoramidite chemistry and DMTr/iBu/Bz-protected monomers. Isolation of i...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19cd950c6a227a9d7b0303f3bf97215c
https://doi.org/10.1021/op060133q
https://doi.org/10.1021/op060133q
Publikováno v:
Organic Process Research & Development. 9:98-101
We have developed a novel method for the large-scale manufacturing of peptides in solution called DioRaSSP. It combines the advantages of the homogeneous character of classical solution-phase synthesis with the generic character and the amenability t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d1d3cefc6475b6a10f163226050258a
https://doi.org/10.1021/op049864l
https://doi.org/10.1021/op049864l
Autor:
Paul B. W. Ten Kortenaar, Gerard N. Wagenaars, Piet J. M. Van den Oetelaar, Peter S.L. Jansen, Pedro A.T.A. Melgers
Publikováno v:
Journal of Controlled Release. 21:11-21
Pharmaceutical development of peptide and protein drugs presents new problems in the area of stability assessment. Generally, these products require more analytical effort than more classic drugs; this may even dictate the speed of progress in certai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ed3c8e6a92fa3f14d8a627e19e9db71
https://doi.org/10.1016/0168-3659(92)90004-b
https://doi.org/10.1016/0168-3659(92)90004-b
Autor:
Paul B. W. Ten Kortenaar, Knut Adermann, Axel Schulz, Frits T. Bakelaar, Wolf-Georg Forssmann, Ivo Franci Eggen
Publikováno v:
Understanding Biology Using Peptides ISBN: 9780387265698
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bccf2175058c18c96f80b795ef291a76
https://doi.org/10.1007/978-0-387-26575-9_62
https://doi.org/10.1007/978-0-387-26575-9_62
Autor:
Ivo Franci Eggen, Fekri El Bellaj, Nicole H. S. Ankone, Erik J. M. Ter Voert, Annet Petersen, Marjolein J. Hartsuiker, Frits T. Bakelaar, Henk E. J. M. Bijsterveld, Gilbert H. L. Bours, Paul B. W. Ten Kortenaar, Gert Jan Kuiper
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 11(10)
A novel method was developed for the large-scale manufacture of peptides in solution, called DioRaSSP-Diosynth Rapid Solution Synthesis of Peptides. This method combines the advantages of the homogeneous character of classical solution-phase synthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9238567d9d9e620066c14c75afd3fed8
https://pubmed.ncbi.nlm.nih.gov/15880381
https://pubmed.ncbi.nlm.nih.gov/15880381
Increased HIV-2 sensitivity of the Vironostika anti-HTLV-III test by addition of a synthetic peptide
Autor:
Paul B. W. Ten Kortenaar, Bert M. M. Hendrix, Wendy J. van Woerkom, Henk J. Theunissen, Erik D. Sprengers
Publikováno v:
Peptides 1990 ISBN: 9789072199089
Peptides 1990
Peptides 1990
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5da7aadd02390a877693bc37d07df134
https://doi.org/10.1007/978-94-011-3034-9_374
https://doi.org/10.1007/978-94-011-3034-9_374
Autor:
Lee G. Pedersen, Paul B. W. Ten Kortenaar, Mary E. Scott, Karl A. Koehler, Richard G. Hiskey, Joseph A. Helpern, Norman T. Boggs, Martha M. Sarasua
Publikováno v:
Journal of the American Chemical Society. 102:3404-3412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::481c1250924f09d86bf034a02a95a9dc
https://doi.org/10.1021/ja00530a017
https://doi.org/10.1021/ja00530a017
Publikováno v:
Collection of Czechoslovak Chemical Communications. 53:2537-2541
The feasibility of the synthesis of assymetric disulfide-containing peptides on solid phase resins was investigated. Using a fragment of [8-arginine]vasopressin as a model, the conversion of the S-acetamidomethylcysteine-containing peptide-resin into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c8b6c176299e918454e370f3b26ae94
https://doi.org/10.1135/cccc19882537
https://doi.org/10.1135/cccc19882537