Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Paul B. Vander"'
Autor:
Megan G. Massa, Rachel L. Scott, Alexandra L. Cara, Laura R. Cortes, Paul B. Vander, Norma P. Sandoval, Jae W. Park, Sahara L. Ali, Leandro M. Velez, Huei-Bin Wang, Shomik S. Ati, Bethlehem Tesfaye, Karen Reue, J. Edward van Veen, Marcus M. Seldin, Stephanie M. Correa
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107918- (2023)
Summary: Balance between metabolic and reproductive processes is important for survival, particularly in mammals that gestate their young. How the nervous system coordinates this balance is an active area of study. Herein, we demonstrate that somatos
Externí odkaz:
https://doaj.org/article/abbbb7899b594e65a4ea56c2463a2e6e
Autor:
Jessica L. Cote, Paul B. Vander, Michael Ellis, Joel M. Cline, Nadezhda Svezhova, Michael E. Doche, Travis J. Maures, Tahrim A. Choudhury, Seongbae Kong, Olivia G. J. Klaft, Ray M. Joe, Lawrence S. Argetsinger, Christin Carter-Su
Publikováno v:
J Cell Sci
The adapter protein SH2B1 is recruited to neurotrophin receptors, including TrkB (also known as NTRK2), the receptor for brain-derived neurotrophic factor (BDNF). Herein, we demonstrate that the four alternatively spliced isoforms of SH2B1 (SH2B1α
Autor:
Christin Carter-Su, Martin G. Myers, Jr, Ormond A. MacDougald, Gowri Chandrashekar, Erik S. Clutter, Abrielle M. Cacciaglia, Paul B. Vander, Devika P. Bagchi, Alexander H. Bedard, Lauren C. DeSantis, Joel M. Cline, Alan C. Rupp, Anabel Flores, Lawrence S. Argetsinger, Jessica L. Cote, Ada Admin
Mice lacking SH2B1 and humans with inactivating mutations of SH2B1 display severe obesity and insulin resistance. SH2B1 is an adapter protein that is recruited to the receptors of multiple hormones and neurotrophic factors. Of the four known alternat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a79c3cf7a5184c1d76cfda90893f0213
https://doi.org/10.2337/figshare.13229090.v1
https://doi.org/10.2337/figshare.13229090.v1
Autor:
Joel M. Cline, Michael E. Doche, Ray M. Joe, Heimo Riedel, Paul B. Vander, Christin Carter-Su, Anabel Flores, Erik S. Clutter, Lawrence S. Argetsinger
Publikováno v:
Molecular and Cellular Biology. 38
The scaffold protein SH2B1, a major regulator of body weight, is recruited to the receptors of multiple cytokines and growth factors, including nerve growth factor (NGF). The β isoform but not the α isoform of SH2B1 greatly enhances NGF-dependent n