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Autor:
Sa V. Ho, Kevin J. Rust, Alan K. Hunter, John T. Herberg, Joseph K. McLaughlin, Robert E. Shell, Kristen E. Thomas, Paul B. Lanter, Robert L. Dufield, Bruce F. Bishop, Maire H. Caparon, Xing Wang
Publikováno v:
Biotechnology and Bioengineering. 105:239-249
Apolipoprotein A 1 Milano (ApoA-1M), the protein component of a high-density lipoprotein (HDL) mimic with promising potential for reduction of atherosclerotic plaque, is produced at large scale by expression in E. coli. Significant difficulty with cl