Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Paul B. Huleatt"'
Autor:
David P. Sheela, Beáta Sperlágh, Tiong Wei Tan, Mui Ling Khoo, Yi Yuan Chua, Ruth Deme, Balázs Balogh, Kálmán Magyar, Flóra Gölöncsér, Christina L. L. Chai, Paul B. Huleatt, Péter Mátyus, Han Kiat Ho, Rou Shen Liew
Publikováno v:
Journal of Medicinal Chemistry. 58:1400-1419
To develop novel neuroprotective agents, a library of novel arylalkenylpropargylamines was synthesized and tested for inhibitory activities against monoamine oxidases. From this, a number of highly potent and selective monoamine oxidase B inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079b2e214d527c4275d8ea0be05e54fd
https://doi.org/10.1021/jm501722s
https://doi.org/10.1021/jm501722s
Publikováno v:
Tetrahedron Letters. 52:1339-1342
A concise, efficient and simple route to a series of bromoindole building blocks is described. The synthetic routes are highlighted by purification-free preparation of o-nitrocinnamate intermediates and clean, modified Cadogan indole syntheses. The s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3c54198e23fd6f4ee42c3694eca2b6c
https://doi.org/10.1016/j.tetlet.2011.01.076
https://doi.org/10.1016/j.tetlet.2011.01.076
Publikováno v:
The Journal of Organic Chemistry. 73:9177-9180
formula chem. An unprecedented synthesis of a range of high value homo-and heterobiindolyls is presented. The one-pot Miyaura borylation and subsequent Suzuki-Miyaura coupling sequence allows for the construction of the highly sterically congested C-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1f94dbe6f03d69aa2426265efaedc0
https://doi.org/10.1021/jo801846b
https://doi.org/10.1021/jo801846b
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:5991-5995
Several derivatives of the natural scabrosin esters were synthesized in order to elucidate the structural features present, which are responsible for the biological activities. The studies demonstrate that full anti-proliferative activities of the sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71b3a453699010d099fa052a9ba65ea
https://doi.org/10.1016/j.bmc.2004.08.015
https://doi.org/10.1016/j.bmc.2004.08.015
Autor:
Paul B. Huleatt, Barbara A. Messerle, Joanne H. H. Ho, Christina L. L. Chai, Selvasothi Selvaratnam
Publikováno v:
Tetrahedron Letters. 50:1125-1127
The versatile and efficient synthesis of a variety of spiroketal motifs via the double intramolecular hydroalkoxylation of aliphatic and aromatic alkyne diols was achieved using simple and readily accessible Ir(I) and Rh(I) cyclooctadiene complexes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d245e510ef191642794608afe5d14c2
https://doi.org/10.1016/j.tetlet.2008.12.075
https://doi.org/10.1016/j.tetlet.2008.12.075
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :389-392
Polarographic stufies of 3,6-epidithiopiperazine-2,5-diones (ETP) including naturally occurring gliotoxin and simple synyhetic analogues are pertinent to understanding their biological action; coulometric measurements on 1,4-diethyl ETP in acetonitri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad24ec594f9a2f888d453f8a8e6028fb
https://doi.org/10.1039/a809266d
https://doi.org/10.1039/a809266d
Publikováno v:
Tetrahedron Letters. 49:5309-5311
The synthesis of 3-, 4-, 7-bromo and 4,7-dibrominated 5,6-dihydroxyindole (DHI) and 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives is reported. Hemetsberger and Bartoli indole syntheses were investigated and expedient routes to the desired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::973509afe099bd7f1b5a39c664446d71
https://doi.org/10.1016/j.tetlet.2008.06.080
https://doi.org/10.1016/j.tetlet.2008.06.080
Publikováno v:
ChemInform. 44
In the presence of a Cu(I)/NHC catalyst, the reactions of allylboronic pinacol esters with CO2 (1 atm) are highly regioselective, giving exclusively the more substituted β,γ-unsaturated carboxylic acids in most cases. A diverse array of substituted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4117a2767ff194451c8017ec2b93424
https://doi.org/10.1002/chin.201350055
https://doi.org/10.1002/chin.201350055
Publikováno v:
Organic letters. 15(15)
In the presence of a Cu(I)/NHC catalyst, the reactions of allylboronic pinacol esters with CO2 (1 atm) are highly regioselective, giving exclusively the more substituted β,γ-unsaturated carboxylic acids in most cases. A diverse array of substituted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dbfcd4bf0d8f51b265b8f153dc3065
https://pubmed.ncbi.nlm.nih.gov/23865385
https://pubmed.ncbi.nlm.nih.gov/23865385
Publikováno v:
Tetrahedron Letters. 44:263-265
Mild methods for controlled C- and N-alkylation of 3-benzyloxycarbonylpiperazine-2,5-diones are reported. The benzyloxylcarbonyl substituent can also serve as latent functionality for N-acyliminium ion formation and subsequent trapping enables instal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e58e168c4c26b7986678f3ccf171a372
https://doi.org/10.1016/s0040-4039(02)02571-6
https://doi.org/10.1016/s0040-4039(02)02571-6