Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Paul B Sinclair"'
Autor:
Paul B. Sinclair, Ruth E. Cranston, Prahlad Raninga, Joanna Cheng, Rebecca Hanna, Zoe Hawking, Steven Hair, Sarra L. Ryan, Amir Enshaei, Sirintra Nakjang, Vikki Rand, Helen J. Blair, Anthony V. Moorman, Olaf Heidenreich, Christine J. Harrison
Publikováno v:
Leukemia. 37:636-649
A common problem in the study of human malignancy is the elucidation of cancer driver mechanisms associated with recurrent deletion of regions containing multiple genes. Taking B-cell acute lymphoblastic leukaemia (B-ALL) and large deletions of 6q [d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95ccc2160b30d60b2c3c0b3b3ac00c89
https://doi.org/10.1038/s41375-023-01816-0
https://doi.org/10.1038/s41375-023-01816-0
Autor:
Qingsong Gao, Sarra L Ryan, Ilaria Iacobucci, Pankaj S Ghate, Ruth E Cranston, Claire J Schwab, Abdelrahman H. Elsayed, Lei Shi, Stanley B Pounds, Shaohua Lei, Pradyumna Baviskar, Deqing Pei, Cheng Cheng, Matthew Bashton, Paul B Sinclair, David R Bentley, Mark Ross, Zoya Kingsbury, Terena James, Kathryn G Roberts, Meenakshi Devidas, Yiping Fan, Wenan Chen, Ti-Cheng Chang, Gang Wu, Andrew J. Carroll, Nyla A. Heerema, Virginia Valentine, Marcus B Valentine, Wenjian Yang, Jun J. Yang, Anthony V Moorman, Christine J Harrison, Charles G. Mullighan
Publikováno v:
Blood Journal.
Intrachromosomal amplification of chromosome 21 defines a subtype of high-risk childhood acute lymphoblastic leukemia (iAMP21-ALL) characterized by copy number changes and complex rearrangements of chromosome 21. The genomic basis of iAMP21-ALL and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6e66ea4f244562e6518a49d46516ddf
https://doi.org/10.1182/blood.2022019094
https://doi.org/10.1182/blood.2022019094
Autor:
Paul. B. Sinclair, Helen H. Blair, Sarra L. Ryan, Lars Buechler, Joanna Cheng, Jake Clayton, Rebecca Hanna, Shaun Hollern, Zoe Hawking, Matthew Bashton, Claire J. Schwab, Lisa Jones, Lisa J. Russell, Helen Marr, Peter Carey, Christina Halsey, Olaf Heidenreich, Anthony V. Moorman, Christine J. Harrison
Publikováno v:
Haematologica, Vol 103, Iss 4 (2018)
Intrachromosomal amplification of chromosome 21 is a heterogeneous chromosomal rearrangement occurring in 2% of cases of childhood precursor B-cell acute lymphoblastic leukemia. These abnormalities are too complex to engineer faithfully in animal mod
Externí odkaz:
https://doaj.org/article/061b963a6e4f465eb098f328b26facdc
Autor:
Paul B, Sinclair, Amani, Sorour, Mary, Martineau, Christine J, Harrison, Wayne A, Mitchell, Elena, O'Neill, Letizia, Foroni
Publikováno v:
Cancer research. 64(12)
With the objective of identifying candidate tumor suppressor genes, we used fluorescence in situ hybridization to map leukemia-related deletions of the long arm of chromosome 6 (6q). Twenty of 24 deletions overlapped to define a 4.8-Mb region of mini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::429475f4339ef5bb7c6432495f26852a
https://pubmed.ncbi.nlm.nih.gov/15205317
https://pubmed.ncbi.nlm.nih.gov/15205317