Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Paul B, Rosenberg"'
Autor:
Pranitha Y. Premnath, Joseph J. Locascio, Kayden J. Mimmack, Christopher Gonzalez, Michael J. Properzi, Onyinye Udeogu, Paul B. Rosenberg, Gad A. Marshall, Jennifer R. Gatchel, for the Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 1, Pp n/a-n/a (2024)
Abstract Introduction It is important to study apathy in Alzheimer's disease (AD) to better understand its underlying neurobiology and develop effective interventions. In the current study, we sought to examine the relationships between longitudinal
Externí odkaz:
https://doaj.org/article/ce32159cccec40cc9e4fb734243bad3a
Autor:
Ana Sofía Ríos, Simón Oxenford, Clemens Neudorfer, Konstantin Butenko, Ningfei Li, Nanditha Rajamani, Alexandre Boutet, Gavin J. B. Elias, Jurgen Germann, Aaron Loh, Wissam Deeb, Fuyixue Wang, Kawin Setsompop, Bryan Salvato, Leonardo Brito de Almeida, Kelly D. Foote, Robert Amaral, Paul B. Rosenberg, David F. Tang-Wai, David A. Wolk, Anna D. Burke, Stephen Salloway, Marwan N. Sabbagh, M. Mallar Chakravarty, Gwenn S. Smith, Constantine G. Lyketsos, Michael S. Okun, William S. Anderson, Zoltan Mari, Francisco A. Ponce, Andres M. Lozano, Andreas Horn
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Deep brain stimulation has been investigated as a potential treatment for cognitive impairments in Alzheimer’s disease. Here the authors carry out post hoc analysis of multi-center cohorts to investigate the anatomical and functional correlates of
Externí odkaz:
https://doaj.org/article/44042e8fc7c347909735b26f535f79b5
Autor:
Emily D. Clark, Jamie Perin, Nathan Herrmann, Olga Brawman‐Mintzer, Krista L. Lanctôt, Alan J. Lerner, Jacobo Mintzer, Prasad R. Padala, Paul B. Rosenberg, Susie Sami, David M. Shade, Christopher H. vanDyck, Anton P. Porsteinsson, for the ADMET‐2 Study Group
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 3, Pp n/a-n/a (2023)
Abstract INTRODUCTION Methylphenidate has been shown to improve apathy in patients with Alzheimer's disease (AD). The authors evaluated the impact of methylphenidate on neuropsychiatric symptoms (NPS) of AD, excluding apathy, using data from the Apat
Externí odkaz:
https://doaj.org/article/210c2f57d74546589949dbe33b0bd416
Autor:
Ram Sagar, Ioannis Azoidis, Cristina Zivko, Ariadni Xydia, Esther S. Oh, Paul B. Rosenberg, Constantine G. Lyketsos, Vasiliki Mahairaki, Dimitrios Avramopoulos
Publikováno v:
Cells, Vol 12, Iss 15, p 1990 (2023)
The recent advances in creating pluripotent stem cells from somatic cells and differentiating them into a variety of cell types is allowing us to study them without the caveats associated with disease-related changes. We generated induced Pluripotent
Externí odkaz:
https://doaj.org/article/8a7c2e03e94344fca33a3ff8a19c8b82
Autor:
Rebecca J. Wilson, Scott P. Lyons, Timothy R. Koves, Victoria G. Bryson, Hengtao Zhang, TianYu Li, Scott B. Crown, Jin-Dong Ding, Paul A. Grimsrud, Paul B. Rosenberg, Deborah M. Muoio
Publikováno v:
Molecular Metabolism, Vol 57, Iss , Pp 101429- (2022)
Objective: Stromal interaction molecule 1 (STIM1) is a single-pass transmembrane endoplasmic/sarcoplasmic reticulum (E/SR) protein recognized for its role in a store operated Ca2+ entry (SOCE), an ancient and ubiquitous signaling pathway. Whereas STI
Externí odkaz:
https://doaj.org/article/64af5c6488244928abf80bd0658ef3e5
Autor:
Navid A. Nafissi, MD, Marat Fudim, MD, Carmelo A. Milano, MD, Paul B. Rosenberg, MD, Adam D. DeVore, MD, MHS, Richa Agarwal, MD
Publikováno v:
JACC: Case Reports, Vol 1, Iss 4, Pp 588-591 (2019)
We describe a case of inherited restrictive cardiomyopathy in a patient presenting with severe biatrial enlargement. We review the evaluation and management of restrictive cardiomyopathy with a focus on genetic etiologies. (Level of Difficulty: Inter
Externí odkaz:
https://doaj.org/article/a450bc6a16fd47d5bf0738ae6cfe1242
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 333-339 (2019)
Abstract Introduction Neuropsychiatric symptoms (NPSs) are nearly universal in cognitive disorders. The mild behavioral impairment construct postulates that NPS may be the first symptom of impending dementia. Methods Participants were cognitively nor
Externí odkaz:
https://doaj.org/article/b799707000234171be9d84a5d5dd517b
Autor:
Hengtao Zhang, Victoria Graham Bryson, Chaojian Wang, TianYu Li, Jaclyn P. Kerr, Rebecca Wilson, Deborah M. Muoio, Robert J. Bloch, Christopher Ward, Paul B. Rosenberg
Publikováno v:
JCI Insight, Vol 6, Iss 17 (2021)
Stromal interaction molecule 1 (STIM1), the sarcoplasmic reticulum (SR) transmembrane protein, activates store-operated Ca2+ entry (SOCE) in skeletal muscle and, thereby, coordinates Ca2+ homeostasis, Ca2+-dependent gene expression, and contractility
Externí odkaz:
https://doaj.org/article/4ef5dfde9ee943f784bb8eee0d805e3a
β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility
Autor:
Jihee Kim, Chad A. Grotegut, James W. Wisler, Tianyu Li, Lan Mao, Minyong Chen, Wei Chen, Paul B. Rosenberg, Howard A. Rockman, Robert J. Lefkowitz
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Background β2-adrenergic receptors (β2ARs) are the target of catecholamines and play fundamental roles in cardiovascular, pulmonary, and skeletal muscle physiology. An important action of β2AR stimulation on skeletal muscle is anabolic gr
Externí odkaz:
https://doaj.org/article/23829cd6bf1d4dbe84a5e0112c5c0274
Autor:
Krista L. Lanctôt, Clara Chen, Ethan Mah, Alex Kiss, Abby Li, Dave Shade, Roberta W. Scherer, Danielle Vieira, Hamadou Coulibaly, Paul B. Rosenberg, Alan J. Lerner, Prasad R. Padala, Olga Brawman-Mintzer, Christopher H. van Dyck, Anton P. Porsteinsson, Suzanne Craft, Allan Levey, William J. Burke, Jacobo Mintzer, Nathan Herrmann
Publikováno v:
International Psychogeriatrics. :1-9
Background: This paper used data from the Apathy in Dementia Methylphenidate Trial 2 (NCT02346201) to conduct a planned cost consequence analysis to investigate whether treatment of apathy with methylphenidate is economically attractive. Methods: A t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ffcbdcf06a86a605c613a294dd1c8d0
https://doi.org/10.1017/s1041610223000327
https://doi.org/10.1017/s1041610223000327