Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Paul Anthony Martinez"'
Autor:
Anna Masato, Nicoletta Plotegher, Francesca Terrin, Michele Sandre, Gaia Faustini, Andrea Thor, Stephen Adams, Giulia Berti, Susanna Cogo, Federica De Lazzari, Camilla Maria Fontana, Paul Anthony Martinez, Randy Strong, Rina Bandopadhyay, Marco Bisaglia, Arianna Bellucci, Elisa Greggio, Luisa Dalla Valle, Daniela Boassa, Luigi Bubacco
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-24 (2023)
Abstract Dopamine dyshomeostasis has been acknowledged among the determinants of nigrostriatal neuron degeneration in Parkinson’s disease (PD). Several studies in experimental models and postmortem PD patients underlined increasing levels of the do
Externí odkaz:
https://doaj.org/article/cf79d21672c5410c9590d5ad6ce4d10a
Autor:
Paul Anthony Martinez, Vanessa Elia Martinez, Sheela Rani, Meredith Murrell, Martin Javors, Jonathan Gelfond, Jonathan Alan Doorn, Elizabeth Fernandez, Randy Strong
Publikováno v:
Brain and Behavior, Vol 13, Iss 9, Pp n/a-n/a (2023)
Abstract Introduction The discovery of biogenic aldehydes in the postmortem parkinsonian brain and the ability of these aldehydes to modify and cross‐link proteins has called attention to their possible role in Parkinson's disease. For example, man
Externí odkaz:
https://doaj.org/article/1909e760b5884f82952cf48691f33b07
Autor:
Margaret Chia-Ying Wey, Elizabeth Fernandez, Paul Anthony Martinez, Patricia Sullivan, David S Goldstein, Randy Strong
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31522 (2012)
Previous studies have reported elevated levels of biogenic aldehydes in the brains of patients with Parkinson's disease (PD). In the brain, aldehydes are primarily detoxified by aldehyde dehydrogenases (ALDH). Reduced ALDH1 expression in surviving mi
Externí odkaz:
https://doaj.org/article/9993ca5b7dd246899f27083e23862635
Autor:
Elizabeth Fernandez, Adam B. Salmon, Martin A. Javors, Molly A. Bogue, Paul Anthony Martinez, Martin S. Denzel, David M. Sabatini, David E. Harrison, Karyn L. Hamilton, João Pedro de Magalhães, Dudley W. Lamming, James F. Nelson, Joe M. McCord, Richard A. Miller, Arlan Richardson, Randy Strong, Juliet Ndukum, Benjamin F. Miller, G. Ed Rainger, Wilma T. Steegenga, James W. Simpkins, Clinton M. Astle, Michael Müller, Nancy L. Nadon, Kevin Flurkey, Adam Antebi
Publikováno v:
Aging Cell
AGING CELL
Aging Cell, 15(5), 872-884
Wiley
Aging Cell 15 (2016) 5
AGING CELL
Aging Cell, 15(5), 872-884
Wiley
Aging Cell 15 (2016) 5
The National Institute on Aging Interventions Testing Program (ITP) evaluates agents hypothesized to increase healthy lifespan in genetically heterogeneous mice. Each compound is tested in parallel at three sites, and all results are published. We re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bf850fe56f49faa91287f8151c0385
http://europepmc.org/articles/PMC5013015
http://europepmc.org/articles/PMC5013015
Autor:
Paul Anthony Martinez, Jun Zhang, Weiping Zhang, Chengjie Song, Shasha Qi, John Paul Andersen, Nicolas Musi, Jia Nie, Yuguang Shi, Randy Strong, Xiaoyang Zhang, Zhen Liu, Yue Zheng
Publikováno v:
Aging Cell
Cardiolipin (CL) is a mitochondrial signature phospholipid that is required for membrane structure, respiration, dynamics, and mitophagy. Oxidative damage of CL by reactive oxygen species is implicated in the pathogenesis of Parkinson's disease (PD),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28459f6eb861f5063c9dac84103196a
https://pubmed.ncbi.nlm.nih.gov/30838774
https://pubmed.ncbi.nlm.nih.gov/30838774
Autor:
Xiang Bai, Paul Anthony Martinez, Randy Strong, Chao Shi, Margaret Chia-Ying Wey, Elizabeth Fernandez
Publikováno v:
Pathobiology of Aging & Age-related Diseases, Vol 7, Iss 1 (2017)
Pathobiology of Aging & Age Related Diseases
Pathobiology of Aging & Age Related Diseases
Considerable evidence suggests that oxidative stress plays a role in the pathogenesis of Parkinson’s disease (PD), the most prevalent neurodegenerative movement disorder. Reduced expression of aldehyde dehydrogenase-1 (ALDH1) and glutathione peroxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c67eb18680a88055690073621c0f3c
https://doi.org/10.1080/20010001.2017.1267855
https://doi.org/10.1080/20010001.2017.1267855
Autor:
David Goldstein, Patricia Sullivan, Shou Shu Wang, Vanessa Martinez, Paul Anthony Martinez, Randy Strong, Elizabeth Fernandez, Margaret Chia-Ying Wey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9f658de326a3823ad6ea53f292cf85c
https://doi.org/10.1016/b978-0-12-800044-1.00071-4
https://doi.org/10.1016/b978-0-12-800044-1.00071-4
Autor:
Paul Anthony Martinez, Randy Strong, Jason C. O'Connor, Cang Chen, Laney Redus, Xiuhua Li, Senlin Li
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e71341 (2013)
PLoS ONE, Vol 8, Iss 8, p e71341 (2013)
Parkinson's disease (PD) is a neurodegenerative disorder primarily characterized by progressive loss of dopamine neurons, leading to loss of motor coordination. However, PD is associated with a high rate of non-motor neuropsychiatric comorbities that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d172257bb7acf3f287ae7dfcd8f50c4a
https://pubmed.ncbi.nlm.nih.gov/23977020
https://pubmed.ncbi.nlm.nih.gov/23977020
Autor:
A. Joshi, Alan Frazer, Paul Anthony Martinez, Randy Strong, Alexandra Estela Soto-Pina, M.K. Green, C.S.S. Rani, David A. Morilak
Publikováno v:
Neuroscience. 192
Stress is a risk factor for the development of affective disorders, including depression, post-traumatic stress disorder, and other anxiety disorders. However, not all individuals who experience either chronic stress or traumatic acute stress develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78cc5cec2ab7f4438306610f2833d37e
https://pubmed.ncbi.nlm.nih.gov/21723377
https://pubmed.ncbi.nlm.nih.gov/21723377