Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Paul A. Spagnuolo"'
Autor:
Varsha Jayasankar, Nikolina Vrdoljak, Alessia Roma, Nawaz Ahmed, Matthew Tcheng, Mark D. Minden, Paul A. Spagnuolo
Publikováno v:
ACS Omega, Vol 7, Iss 2, Pp 1682-1693 (2022)
Externí odkaz:
https://doaj.org/article/d27f98b1386b4451bd5031a57dcd5a79
Autor:
Alessia Roma, Matthew Tcheng, Nawaz Ahmed, Sarah Walker, Preethi Jayanth, Mark D. Minden, Julie A. Reisz, Angelo D'Alessandro, Jakub Rohlena, Paul A. Spagnuolo
Publikováno v:
Phytomedicine Plus, Vol 2, Iss 3, Pp 100300- (2022)
Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy that results from the accumulation of undifferentiated myeloid cells in the peripheral blood and bone marrow. Limited therapeutics contribute to unfavorable patient outcomes, high
Externí odkaz:
https://doaj.org/article/d6cba8b6f3d64bb79a2161045226f5c7
Autor:
Mónica Lara-Márquez, Marisol Báez-Magaña, Cristina Raymundo-Ramos, Paul A. Spagnuolo, Lourdes Macías-Rodríguez, Rafael Salgado-Garciglia, Alejandra Ochoa-Zarzosa, Joel E. López-Meza
Publikováno v:
Journal of Functional Foods, Vol 64, Iss , Pp 103658- (2020)
Colorectal cancer (CRC) is the third most common type of cancer worldwide. Chemotherapy used in CRC patients has severe side effects. As an alternative, the search to identify natural compounds increases the opportunity to select therapeutics. In thi
Externí odkaz:
https://doaj.org/article/2c7cd03f0d094012ba1260ba8d4914df
Autor:
Sohrab N. Ali, Thamara K. Dayarathna, Aymon N. Ali, Tijani Osumah, Mohamed Ahmed, Tyler T. Cooper, Nicholas E. Power, Dongxing Zhang, Dajung Kim, Rachel Kim, Andre St. Amant, Jinqiang Hou, Thomas Tailly, Jun Yang, Len Luyt, Paul A. Spagnuolo, Jeremy P. Burton, Hassan Razvi, Hon S. Leong
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 11 (2018)
Kidney stone disease involves the aggregation of stone-forming salts consequent to solute supersaturation in urine. The development of novel therapeutic agents for this predominantly metabolic and biochemical disorder have been hampered by the lack o
Externí odkaz:
https://doaj.org/article/6f87902d61b54feb83e0b152c99374ab
Autor:
Paul A. Spagnuolo, Angelo D'Alessandro, Rachel Culp-Hill, Julie A. Reisz, Andrew C. Doxey, Jessica Luc, Praveen P. Nekkar Rao, Kristin Hope, Mark D. Minden, Preethi Jayanth, Sarah Walker, Nawaz Ahmed, Matthew Tcheng, Alessia Roma
Supplementary Figure from Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab0cf07dbc910ec9d05a0fcb07970e6
https://doi.org/10.1158/1541-7786.22528076.v1
https://doi.org/10.1158/1541-7786.22528076.v1
Autor:
Paul A. Spagnuolo, Angelo D'Alessandro, Rachel Culp-Hill, Julie A. Reisz, Andrew C. Doxey, Jessica Luc, Praveen P. Nekkar Rao, Kristin Hope, Mark D. Minden, Preethi Jayanth, Sarah Walker, Nawaz Ahmed, Matthew Tcheng, Alessia Roma
Supplementary Data from Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ecf07276bacf58f9440d1b432cabf6
https://doi.org/10.1158/1541-7786.22528079.v1
https://doi.org/10.1158/1541-7786.22528079.v1
Autor:
Paul A. Spagnuolo, Angelo D'Alessandro, Rachel Culp-Hill, Julie A. Reisz, Andrew C. Doxey, Jessica Luc, Praveen P. Nekkar Rao, Kristin Hope, Mark D. Minden, Preethi Jayanth, Sarah Walker, Nawaz Ahmed, Matthew Tcheng, Alessia Roma
Acute myeloid leukemia (AML) is a hematologic malignancy metabolically dependent on oxidative phosphorylation and mitochondrial electron transport chain (ETC) activity. AML cells are distinct from their normal hematopoietic counterparts by this metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e265a1dc866eec9722f84e745fe748f
https://doi.org/10.1158/1541-7786.c.6545609
https://doi.org/10.1158/1541-7786.c.6545609
Autor:
Paul A. Spagnuolo, Aaron D. Schimmer, Joe Quadrilatero, Jamie W. Joseph, Janusz Pawliszyn, Andrea Edginton, Jeffery L. Wrana, Alessandro Datti, Shrivani Sriskanthadevan, Mark Minden, Barbara Bojko, Ezel Boyaci, Marcela Gronda, Xiao Ming Wang, Rose Hurren, Andrew Mitchell, Thomas Hanlon, Sarah-Grace Rota, Leonard Angka, Eric A. Lee
Supplementary Figures S1-S9. Avocatin B is the most active avocado lipid analogue (S1); Kinetics of avocatin B-induced death (S2); Cell cycle analysis of avocatin B treated TEX cells (S3); Avocatin B increases DCFH-DA and DHE (S4); Avocatin B's activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605f187f076ac4f343e40bcbee551bc2
https://doi.org/10.1158/0008-5472.22405770.v1
https://doi.org/10.1158/0008-5472.22405770.v1
Autor:
Paul A. Spagnuolo, Aaron D. Schimmer, Joe Quadrilatero, Jamie W. Joseph, Janusz Pawliszyn, Andrea Edginton, Jeffery L. Wrana, Alessandro Datti, Shrivani Sriskanthadevan, Mark Minden, Barbara Bojko, Ezel Boyaci, Marcela Gronda, Xiao Ming Wang, Rose Hurren, Andrew Mitchell, Thomas Hanlon, Sarah-Grace Rota, Leonard Angka, Eric A. Lee
Legend for Supplementary Figures S1-S9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ad24094a5421bfed1f3de42d7b75ba
https://doi.org/10.1158/0008-5472.22405773
https://doi.org/10.1158/0008-5472.22405773
Autor:
Paul A. Spagnuolo, Aaron D. Schimmer, Joe Quadrilatero, Jamie W. Joseph, Janusz Pawliszyn, Andrea Edginton, Jeffery L. Wrana, Alessandro Datti, Shrivani Sriskanthadevan, Mark Minden, Barbara Bojko, Ezel Boyaci, Marcela Gronda, Xiao Ming Wang, Rose Hurren, Andrew Mitchell, Thomas Hanlon, Sarah-Grace Rota, Leonard Angka, Eric A. Lee
Supplementary Tables S1-S3. Summary of EC50 values for avocatin B in a panel of AML cell lines (S1); AML patient sample details used for annexin/PI (S2); AML patient sample details used for colony formation assays (S3).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16fda7d4d735fb11d6d5fe58353b192
https://doi.org/10.1158/0008-5472.22405764.v1
https://doi.org/10.1158/0008-5472.22405764.v1