Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Paul A. Slatford"'
Autor:
Jonathan M. J. Williams, James E. Taylor, Michael K. Whittlesey, Paul A. Slatford, Simon J. Pridmore
Publikováno v:
Tetrahedron. 65:8981-8986
Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)3(CO)H2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions.
Publikováno v:
Angewandte Chemie. 121:6380-6383
Publikováno v:
Tetrahedron: Asymmetry. 18:2845-2848
An asymmetric C–C bond formation has been achieved by iridium-catalysed coupling of benzyl alcohol with a phosphonium ylide using a borrowing hydrogen strategy.
Autor:
Jonathan M. J. Williams, Aurelie Daniel, Simon J. Pridmore, Michael K. Whittlesey, Paul A. Slatford
Publikováno v:
Tetrahedron Letters. 48:5115-5120
Various 1,2,5-substituted pyrroles have been synthesised from 1,4-alkynediols using a ruthenium catalysed isomerisation to give the corresponding 1,4-dicarbonyl compounds, which undergo in situ cyclisation to pyrroles in the presence of amine.
Publikováno v:
Tetrahedron Letters. 48:5111-5114
1-4-Alkynediols serve as readily available starting materials for isomerisation to 1,4-diketones, which can be converted in situ into the corresponding furans by acid-catalysed dehydration. A range of 2,5-disubstituted furans was prepared using the r
Autor:
Paul A. Slatford, Jan-Phillip Kaiser, Guy C. Lloyd-Jones, Ian J. S. Fairlamb, Katharine L. Bray
Publikováno v:
Topics in Catalysis. 19:49-59
Optimum conditions for the cycloisomerisation of dimethyldiallylmalonate by complexes of the form [L2PdCl2] (L = RCN or DMSO) were found to be [(t-BuCN)2PdCl2] in 1,2-dichloroethane at 40 °C. These conditions also allow the highly regioselective cyc
Autor:
Jonathan M. J. Williams, Naveen Anand, Nathan A. Owston, Alexandra J. Parker, Paul A. Slatford
Publikováno v:
Tetrahedron Letters. 48:7761-7763
The conversion of oxime ethers into nitriles has been achieved under neutral conditions using Ru(CO)(PPh 3 ) 3 H 2 and the bidentate ligand Xantphos as the catalyst.
Publikováno v:
Tetrahedron Letters. 47:6787-6789
A ruthenium complex of Xantphos has been shown to be a good catalyst for the alkylation of active methylene compounds with a range of alcohols.
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:535-537
A clean and efficient method for the N-alkylation of tryptamine and phenethylamine, employing alcohols as the alkylating agents, has been developed. The reaction proceeds via catalytic electronic activation, involving an iridium catalyst which activa
Autor:
Jonathan M. J. Williams, Simon J. Pridmore, Michael K. Whittlesey, James E. Taylor, Paul A. Slatford
Publikováno v:
ChemInform. 41