Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects.

Autor: Emmanuel S Onaivi, Hiroki Ishiguro, Jian-Ping Gong, Sejal Patel, Paul A Meozzi, Lester Myers, Alex Perchuk, Zoila Mora, Patricia A Tagliaferro, Eileen Gardner, Alicia Brusco, B Emmanuel Akinshola, Bruce Hope, Javier Lujilde, Toshiya Inada, Shinya Iwasaki, David Macharia, Lindsey Teasenfitz, Tadao Arinami, George R Uhl

Publikováno v: PLoS ONE, Vol 3, Iss 2, p e1640 (2008)

BACKGROUND: Addiction and major depression are mental health problems associated with stressful events in life with high relapse and reoccurrence even after treatment. Many laboratories were not able to detect the presence of cannabinoid CB2 receptor

Externí odkaz: https://doaj.org/article/750ceb9521a845bd8f34465651184a8c

Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects

Autor: Tadao Arinami, Alex Perchuk, Javier Lujilde, David Macharia, Paul A. Meozzi, B. Emmanuel Akinshola, Patricia Tagliaferro, Eileen Gardner, George R. Uhl, Lester Myers, Alicia Brusco, Jian Ping Gong, Emmanuel S. Onaivi, Lindsey Teasenfitz, Zoila Mora, Hiroki Ishiguro, Toshiya Inada, Shinya Iwasaki, Bruce T. Hope, Sejal Patel

Publikováno v: PLoS ONE
PLoS ONE, Vol 3, Iss 2, p e1640 (2008)

Background Addiction and major depression are mental health problems associated with stressful events in life with high relapse and reoccurrence even after treatment. Many laboratories were not able to detect the presence of cannabinoid CB2 receptors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee91be02a4bb5dfcdb585a49fbd7a2f9
https://pubmed.ncbi.nlm.nih.gov/18286196

Methods to Study the Behavioral Effects and Expression of CB2 Cannabinoid Receptor and Its Gene Transcripts in the Chronic Mild Stress Model of Depression

Autor: Paul A. Meozzi, George R. Uhl, Hiroki Ishiguro, Claire M. Leonard, Bruce T. Hope, Patel Sejal, Patricia Tagliaferro, Emmanuel S. Onaivi, Lester Myers, Eileen Gardner, Alicia Brusco

Behavioral and molecular methods were used to study and determine whether there is a link between depression that may be a factor in drug/alcohol addiction, and the endocannabinoid hypothesis of substance abuse. Depression is a lack of interest in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e747f4d82cea076ec1272ac97786cf6
https://doi.org/10.1385/1-59259-999-0:291

Functional Expression of Brain Neuronal CB2 Cannabinoid Receptors Are Involved in the Effects of Drugs of Abuse and in Depression.

Autor: Onaivi, Emmanuel S.^1,2 (AUTHOR), Ishiguro, Hiroki^2,3 (AUTHOR), Gong, Jian‐Ping² (AUTHOR), Patel, Sejal¹ (AUTHOR), Meozzi, Paul A.¹ (AUTHOR), Myers, Lester¹ (AUTHOR), Perchuk, Alex¹ (AUTHOR), Mora, Zoila¹ (AUTHOR), Tagliaferro, Patricia A.⁴ (AUTHOR), Gardner, Eileen¹ (AUTHOR), Brusco, Alicia⁴ (AUTHOR), Akinshola, B. Emmanuel⁵ (AUTHOR), Liu, Qing‐Rong² (AUTHOR), Chirwa, Sanika S.⁶ (AUTHOR), Hope, Bruce⁷ (AUTHOR), Lujilde, Javier⁴ (AUTHOR), Inada, Toshiya⁸ (AUTHOR), Iwasaki, Shinya² (AUTHOR), Macharia, David¹ (AUTHOR), Teasenfitz, Lindsey¹ (AUTHOR)

Publikováno v: Annals of the New York Academy of Sciences. Oct2008, Vol. 1139, p434-449. 16p. 4 Diagrams, 1 Chart, 4 Graphs.

Marijuana and Cannabinoid Research : Methods and Protocols

Autor: Onaivi, Emmanuel S.

The revolutionary discovery that the human body and brain make their own marijuana-like substances called endocannabinoids has transformed marijuana-cannabinoid research into a mainstream science impacting our understanding of reproduction, developme