Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Paul A. Jowsey"'
Autor:
Jianquan Li, Nanmao Dang, Nuria Martinez-Lopez, Paul A. Jowsey, Dong Huang, Robert N. Lightowlers, Fei Gao, Jun-Yong Huang
Publikováno v:
Cell Division, Vol 14, Iss 1, Pp 1-15 (2019)
Abstract Background Drugs such as taxanes, epothilones, and vinca alkaloids are widely used in the treatment of breast, ovarian, and lung cancers but come with major side effects such as neuropathy and loss of neutrophils and as single agents have a
Externí odkaz:
https://doaj.org/article/a16ed0bf513c447d9b4284c3f91e72d5
Autor:
Fatemeh Behdani, Seyed Mohammad Hassan Moallem, Mohammad Reza Abbaszadegan, Ali Akhondpour Manteghi, Dorsa Morshedi Rad, Farhad Farid Hosseini, Paul A. Jowsey, Amir Hooshang Mohammadpour, Mahnaz Ahmadimanesh, Fatemeh Shabani Behbahani, Mohammad Hossein Ghahremani, Leila Etemad, Seyed Adel Moallem
Publikováno v:
Journal of psychopharmacology (Oxford, England). 33(11)
Background: The relationship between depression and increased oxidative stress is well known. DNA damage by oxidation factors is an important cause of the aging process in psychiatric disorders. Aims: Owing to the scarcity of human studies and high i
Autor:
Jun-Yong Huang, Jianquan Li, Robert N. Lightowlers, Nuria Martinez-Lopez, Fei Gao, Dong Huang, Nanmao Dang, Paul A. Jowsey
Publikováno v:
Cell Division
Cell Division, Vol 14, Iss 1, Pp 1-15 (2019)
Cell Division, Vol 14, Iss 1, Pp 1-15 (2019)
Background\ud Drugs such as taxanes, epothilones, and vinca alkaloids are widely used in the treatment of breast, ovarian, and lung cancers but come with major side effects such as neuropathy and loss of neutrophils and as single agents have a lack o
Autor:
Stephanie K, Meyer, Michael, Dunn, Daniel S, Vidler, Andrew, Porter, Peter G, Blain, Paul A, Jowsey
Publikováno v:
The FASEB Journal
Microcephalin-1 (MCPH1) exists as 2 isoforms that regulate cyclin-dependent kinase-1 activation and chromosome condensation during mitosis, with MCPH1 mutations causing primary microcephaly. MCPH1 is also a tumor suppressor protein, with roles in DNA
Autor:
John Rouse, Paul A. Jowsey, Nicholas A. Morrice, Hilary MacLauchlan, Rachel Toth, C. James Hastie
Publikováno v:
DNA repair. 65
Autor:
Andrew A. Axon, Paul A. Jowsey, Karen Wallace, Matthew C. Wright, Fouzeyyah Alsaeedi, Emma A. Fairhall, Stephanie K. Meyer, Fiona Oakley, Philip M. E. Probert, Michelle Charles, Peter G. Blain
Publikováno v:
Toxicology Research. 4:203-222
The B-13 cell is a readily expandable rat pancreatic acinar-like cell that differentiates on simple plastic culture substrata into replicatively-senescent hepatocyte-like (B-13/H) cells in response to glucocorticoid exposure. B-13/H cells express a v
Autor:
Peter G. Blain, Paul A. Jowsey
Publikováno v:
Toxicology Letters. 232:413-421
Sulphur mustard (SM) is a vesicating agent that has been used several times as a weapon during military conflict and continues to pose a threat as an agent of warfare/terrorism. After exposure, SM exerts both acute and delayed long-term toxic effects
Autor:
Peter G. Blain, Mahmood Sadeghi, Mohammad Reza Soroush, Mahdi Balali-Mood, Effat Behravan, Shahriar Khateri, Faith M. Williams, Paul A. Jowsey
Publikováno v:
Toxicology letters. 293
Delayed effects of sulfur mustard (SM) exposure on the levels of five important damage/repair proteins were investigated in 40 SM-exposed veterans of Iran-Iraq war and 35 unexposed controls. A major DNA damage biomarker protein – phosphorylated H2A
Publikováno v:
Toxicology Letters. 209:1-10
Sulphur mustard (SM) is a blistering agent that causes debilitating damage to the skin, eyes and respiratory system. In cases of severe exposure, immunodepletion can occur as well as death, due to secondary infections. The toxicity of SM is thought t
Publikováno v:
Toxicology. 257:105-112
Sulphur mustard (SM) is a blistering agent that is directly toxic to the skin and mucosal surfaces of the eye and respiratory system. Symptoms take several hours to develop and the mechanism of action is poorly understood although SM is able to alkyl