Zobrazeno 1 - 10
of 281
pro vyhledávání: '"Paul A. Cooke"'
Autor:
Helena D. Zomer, Paul S. Cooke
Publikováno v:
Biology, Vol 13, Iss 5, p 335 (2024)
Companion animal obesity has emerged as a significant veterinary health concern globally, with escalating rates posing challenges for preventive and therapeutic interventions. Obesity not only leads to immediate health problems but also contributes t
Externí odkaz:
https://doaj.org/article/038c838f1a354af2af05e69bfa7e27c2
Autor:
Helena D. Zomer, Paul S. Cooke
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Non-healing skin wounds are disproportionally prevalent in older adults. Current treatments do not account for the particularities of aged skin and result in inadequate outcomes. Overall, healing chronic wounds in the elderly remains a major unmet cl
Externí odkaz:
https://doaj.org/article/f6e5d4f3b2784e8494487666219db08d
Autor:
Ana M. Mesa, Theresa I. Medrano, Vijay K. Sirohi, William H. Walker, Richard D. Johnson, Sergei G. Tevosian, Angie M. Adkin, Paul S. Cooke
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 616-629 (2022)
Brown adipose tissue (BAT) generates heat through non-shivering thermogenesis, and increasing BAT amounts or activity could facilitate obesity treatment and provide metabolic benefits. In mice, BAT has been reported in perirenal, thoracic and cranial
Externí odkaz:
https://doaj.org/article/1494595abbc045c4983e205567fa95d4
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107028- (2023)
Summary: Maternal uterine remodeling facilitates embryo implantation, stromal cell decidualization and placentation, and perturbation of these processes may cause pregnancy loss. Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that
Externí odkaz:
https://doaj.org/article/e60d505507c644da9f0181cba3e94e6b
Autor:
William H. Walker, Paul S. Cooke
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2748 (2023)
Steroid hormones are capable of diffusing through cell membranes to bind with intracellular receptors to regulate numerous physiological processes. Three classes of steroid hormones, namely androgens, estrogens and glucocorticoids, contribute to the
Externí odkaz:
https://doaj.org/article/6b97896e6e8f42fb8c332fff73eec7a6
Autor:
Siddaraju V. Boregowda, Manjunatha K. Nanjappa, Cori N. Booker, Jacqueline Strivelli, Valentina M. Supper, Paul S. Cooke, Donald G. Phinney
Publikováno v:
Biology, Vol 11, Iss 9, p 1257 (2022)
Obesity and type II diabetes mellitus (T2DM) are prominent risk factors for secondary osteoporosis due to the negative impacts of hyperglycemia and excessive body fat on bone metabolism. While the armamentarium of anti-diabetic drugs is expanding, th
Externí odkaz:
https://doaj.org/article/13aa00ddf3634da2bc2ba99743a7517f
Autor:
Paul S. Cooke, William H. Walker
Publikováno v:
Seminars in Cell & Developmental Biology. 121:71-81
Signaling by androgens through androgen receptor (AR) is essential to complete spermatogenesis in the testis. Similarly, loss of the main estrogen receptor, estrogen receptor 1 (ESR1; also known as ERα), results in male infertility, due in part to i
Autor:
Juan J. Aristizabal-Henao, Val Beasley, Brad Bolon, Genevieve S. Bondy, Gary A. Boorman, John A. Bowden, Wayne Carmichael, Vincent Castranova, Peter R. Chai, Phaedra I. Cole, Kathleen M. Colegrove, Paul S. Cooke, T. Zane Davis, Nancy D. Denslow, Susan A. Elmore, Timothy B. Erickson, Charlotte E. Goldfine, Sharon M. Gwaltney-Brant, Wanda M. Haschek, Kathleen Heinz-Taheny, Ann F. Hubbs, Trupti Joshi, Kevin P. Keenan, Eric D. Lombardini, Christopher J. Martyniuk, Anatoly E. Martynyuk, Heike A. Marxfeld, Elizabeth F. McInnes, Robert R. Mercer, Ana M. Mesa, Justin Oguni, Michelle E. Pacheco-Thompson, Sabitha Papineni, Dale W. Porter, Olga M. Pulido, Matthias Rinke, Cheryl S. Rosenfeld, Colin G. Rousseaux, Linda M. Sargent, Frederic Schorsch, Melissa Schutten, Philip Solter, Krishnan Sriram, Bryan L. Stegelmeier, Amy Usborne, Francisco A. Uzal, Kenneth A. Voss, Matthew A. Wallig, Juexin Wang, Kara A. Yeung
Publikováno v:
Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 3 ISBN: 9780443161537
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fc7f3d65b7958cfed723697b0bb6a89
https://doi.org/10.1016/b978-0-443-16153-7.01002-9
https://doi.org/10.1016/b978-0-443-16153-7.01002-9
Autor:
Paul S. Cooke, Cheryl S. Rosenfeld, Nancy D. Denslow, Christopher J. Martyniuk, Ana M. Mesa, John A. Bowden, Trupti Joshi, Juexin Wang, Juan J. Aristizabal-Henao, Anatoly E. Martynyuk
Publikováno v:
Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 3 ISBN: 9780443161537
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d291c479a078eeadf7d8220600d1b30
https://doi.org/10.1016/b978-0-443-16153-7.00012-5
https://doi.org/10.1016/b978-0-443-16153-7.00012-5
Autor:
Amber Derpinghaus, Paul S. Cooke, Laurence S. Baskin, William H. Walker, Mei Cao, Gerald R. Cunha
Publikováno v:
Differentiation. 122:7-16