Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Paul A. Bruno"'
Autor:
Snehal M. Pinto Pereira, Manjula D. Nugawela, Terence Stephenson, Paul Foret-Bruno, Emma Dalrymple, Laila Xu, Elizabeth Whittaker, Isobel Heyman, Tamsin Ford, Terry Segal, Trudie Chalder, Shamez N. Ladhani, Anna A. Mensah, Kelsey McOwat, Ruth Simmons, CLoCk Consortium, Roz Shafran
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Our previous study in children and young people (CYP) at 3- and 6-months post-infection showed that 12–16% of those infected with the Omicron (B.1.1.529) variant of SARS-CoV-2 met the research definition of Long Covid, with no differences
Externí odkaz:
https://doaj.org/article/0800f19653854508bcff204e6457b93a
Autor:
Anna K. Mapp, Laura E. Goo, Julie M. Garlick, Sofia D. Merajver, Steven M. Sturlis, Yejun Liu, Samantha N. De Salle, Liwei Bao, Giselle Tamayo-Castillo, Amanda L. Peiffer, Charles L. Brooks, Joel A. Yates, Paul A. Bruno
Publikováno v:
Journal of the American Chemical Society; Vol. 143 Núm. 25: 2021 pp. 9297-9302
Kérwá
Universidad de Costa Rica
instacron:UCR
J Am Chem Soc
Kérwá
Universidad de Costa Rica
instacron:UCR
J Am Chem Soc
Inhibitors of transcriptional protein–protein interactions (PPIs) have high value both as tools and for therapeutic applications. The PPI network mediated by the transcriptional coactivator Med25, for example, regulates stress-response and motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d303b44c963d7c8cdf1c2780e4fee970
Autor:
Ishna N. Mistry, Philip G. Humphreys, Panagis Filippakopoulos, Amy Hicks, Pavel Guzanov, Laura E. Jennings, Larissa See, Jessica K. Reynolds, Amy R. Scorah, Matthias Schiedel, Anna K. Mapp, James Clayton, David S. Hewings, Paul A. Bruno, Mustafa Moroglu, Charles N. G. Evans, Corentine M.C. Laurin, Stuart J. Conway, Joseph P. Bluck, Ester M. Hammond, Giulia Stazi, Sarah Picaud, Philip C. Biggin
Publikováno v:
Bioorganic & Medicinal Chemistry
Ligands for the bromodomain and extra-terminal domain (BET) family of bromodomains have shown promise as useful therapeutic agents for treating a range of cancers and inflammation. Here we report that our previously developed 3,5-dimethylisoxazole-ba
Publikováno v:
Angewandte Chemie. 128:15221-15225
Aberrant canonical NF-κB signaling is implicated in diseases from autoimmune disorders to cancer. A major therapeutic challenge is the need for selective inhibition of the canonical pathway without impacting the many non-canonical NF-κB functions.
Autor:
Sanjay L. Bhave, Jharna Datta, Anna K. Mapp, Xiujie Xie, Quintin Pan, Manchao Zhang, Longzhu Piao, James C. Lang, Tizhi Su, Paul A. Bruno, Christopher E. Taylor, Theodoros N. Teknos
Publikováno v:
Molecular Cancer Therapeutics. 12:1515-1525
EGF receptor (EGFR) is elevated in more than 90% of head and neck squamous cell carcinoma (HNSCC). However, a majority of patients with HNSCC do not respond to anti-EGFR therapeutics. Insensitivity to EGFR inhibitors may be due to kinase-independent
Publikováno v:
Clinical Chiropractic. 11:4-14
Summary Objective The objective of the current study was to investigate whether any differences exist in the activation patterns of the gluteus maximus (GM), hamstring (HAM), contralateral erector spinae (CES), and ipsilateral erector spinae (IES) mu
Autor:
Jeff Bagust, Paul A. Bruno
Publikováno v:
Clinical Chiropractic. 10:68-80
Summary Objective The objective of this study was to investigate whether any differences exist between subjects with and without low back pain (LBP) in the motor patterns of the gluteus maximus (GM), hamstring (HAM), contralateral erector spinae (CES
Autor:
Jeff Bagust, Paul A. Bruno
Publikováno v:
Clinical Chiropractic. 9:11-20
Summary Objective The objective of this study was to investigate the within-subject and between-subject consistencies of the motor patterns of the gluteus maximus (GM), hamstring (HAM), contralateral erector spinae (CES), and ipsilateral erector spin
Autor:
Paul W. Bruno
Publikováno v:
Science, Politics, and Ontology of Life-Philosophy.
Autor:
Paul Robert Bruno
James G. Scrugham, Nevada's 14 th governor, assumed office during the economic downturn of the early 1920s. The Comstock, and Tonopah - Goldfield mining boom days were in the past, and the new governor made development of a sustainable economic model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47eb59b5efafad31157dae53cd3492dc