Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Paul A Sobotka"'
Autor:
Jie Wang, Yuehui Yin, Chengzhi Lu, Zhibing Lu, Jialu Hu, Yue Wang, Junbo Ge, Hong Jiang, Chen Yao, Xiaoyan Yan, Wei Ma, Xiaoyong Qi, Yi Dang, Shaoliang Chen, Jiancheng Zhu, Dongmei Wang, Chao Ding, Weimin Wang, Jian Liu, Yanbin Wang, Hui Li, Zhenhua Pan, Kaijun Cui, Chengzong Li, Xinjian Liang, Weijie Chen, Paul A. Sobotka, JingJing Zhang, Murray Esler, Ningling Sun, Minglong Chen, Yong Huo
Publikováno v:
EClinicalMedicine, Vol 72, Iss , Pp 102626- (2024)
Summary: Background: Previous trials of renal denervation (RDN) have been designed to investigate reduction of blood pressure (BP) as the primary efficacy endpoint using non-selective RDN without intraoperatively verified RDN success. It is an unmet
Externí odkaz:
https://doaj.org/article/33fb94ed9e164e3bb65a0428d1a4dd42
Autor:
Markus Peter Schlaich, Dagmara eHering, Paul A Sobotka, Henry eKrum, Gavin W Lambert, Elisabeth A Lambert, Murray D Esler
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Increased central sympathetic drive is a hallmark of a number of important and common clinical conditions including essential hypertension, insulin resistance, heart failure, and chronic kidney disease. Afferent signalling from the kidney via sensory
Externí odkaz:
https://doaj.org/article/fc4c2f6013df45afba67c964ad9413aa
Autor:
Abu Baker Sheikh, Paul A. Sobotka, Ishan Garg, Jessilyn P. Dunn, Abdul Mannan Khan Minhas, Md Mobashir Hasan Shandhi, Jeroen Molinger, Barry J. McDonnell, Marat Fudim
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 9 (2023)
Recent advances in wearable technology through convenient and cuffless systems will enable continuous, noninvasive monitoring of blood pressure (BP), heart rate, and heart rhythm on both longitudinal 24‐hour measurement scales and high‐frequency
Externí odkaz:
https://doaj.org/article/8355e082e50f40fc9eb15db1fecd4c20
Autor:
Jie Wang, Ningling Sun, Junbo Ge, Hong Jiang, Yuehui Yin, Minglong Chen, Yue Wang, Chen Yao, Xiaoyan Yan, Paul A. Sobotka, Yong Huo
Publikováno v:
Journal of Cardiovascular Translational Research. 16:358-370
Renal denervation (RDN) is proposed as a durable and patient compliance independent treatment for hypertension. However, 20-30% non-responder after RDN treatment weakened the therapeutic effect, which may be due to blind ablation. The renal nerve map
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21cf5bbef00f0f9fe6ebbaa72b52d41
https://doi.org/10.1007/s12265-022-10307-z
https://doi.org/10.1007/s12265-022-10307-z
Publikováno v:
Interventional Cardiology Clinics. 11:267-277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74d862f68155d556cb3d6462f4c73006
https://doi.org/10.1016/j.iccl.2022.01.005
https://doi.org/10.1016/j.iccl.2022.01.005
Autor:
Krzysztof Narkiewicz, MD, Laura E.K. Ratcliffe, BSc, MBBS, Emma C. Hart, PhD, Linford J.B. Briant, PhD, Marzena Chrostowska, PhD, Jacek Wolf, MD, Anna Szyndler, MD, Dagmara Hering, MD, Ana P. Abdala, PhD, Nathan Manghat, MD, Amy E. Burchell, MA, BMBCh, Claire Durant, PhD, Melvin D. Lobo, Paul A. Sobotka, MD, Nikunj K. Patel, MBBS, MD, James C. Leiter, MD, Zoar J. Engelman, PhD, Angus K. Nightingale, MB, BChir, MD, Julian F.R. Paton, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 5, Pp 313-324 (2016)
Animal and human data indicate pathological afferent signaling emanating from the carotid body that drives sympathetically mediated elevations in blood pressure in conditions of hypertension. This first-in-man, proof-of-principle study tested the saf
Externí odkaz:
https://doaj.org/article/090de4c0ffaa48999a72a1b604d2cccd
Autor:
Christian Ott, Melvin D. Lobo, Paul A. Sobotka, Felix Mahfoud, Alice Stanton, John Cockcroft, Neil Sulke, Eamon Dolan, Markus van der Giet, Joachim Hoyer, Stephen S. Furniss, John P. Foran, Adam Witkowski, Andrzej Januszewicz, Danny Schoors, Konstantinos Tsioufis, Benno J. Rensing, Manish Saxena, Benjamin Scott, G. André Ng, Stephan Achenbach, Roland E. Schmieder, Michael Schmid, Ajay Jain, Charles Knight, Anthony Mathur, Peter Balmforth, Sandra F. Luitjens, Gerard Smits, Dhanraj Mungur, Aleksander Prejbisz, Jacek Kadziela, Elżbieta Florczak, Joseph Galvin, Kyriakos Dimitriadis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 12 (2016)
BackgroundOptions for interventional therapy to lower blood pressure (BP) in patients with treatment‐resistant hypertension include renal denervation and the creation of an arteriovenous anastomosis using the ROX coupler. It has been shown that BP
Externí odkaz:
https://doaj.org/article/32ddedfb0ddf411eb67ff3e3f09c5c67
Autor:
Paul A. Sobotka, Stephen Black, Eric J. Stöhr, Gerard J. O’Sullivan, Peter Balmforth, Rachael Morris, Darren Spencer, Barry J. McDonnell
Publikováno v:
Journal of Cardiovascular Translational Research
Cardiac output during exercise increases by as much as fivefold in the untrained man, and by as much as eightfold in the elite athlete. Increasing venous return is a critical but much overlooked component of the physiological response to exercise. Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f89714013ef3d50550b0df650d7f11
https://doi.org/10.1007/s12265-020-09963-w
https://doi.org/10.1007/s12265-020-09963-w
Autor:
Sanjiv J. Shah, Piotr P. Ponikowski, Vivek Y. Reddy, Manesh R. Patel, Sheldon E. Litwin, Zoar Jacob Engelman, Mark E. Dunlap, Barry A. Borlaug, Paul A. Sobotka, Marat Fudim, Jeroen Molinger, Anisha Bapna, Daniel Burkhoff, Adrian F. Hernandez, G. Michael Felker, Horst Sievert
Publikováno v:
Eur J Heart Fail
Volume recruitment from the splanchnic compartment is an important physiological response to stressors such as physical activity and blood loss. In the setting of heart failure (HF), excess fluid redistribution from this compartment leads to increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0c7a998e2398834f0d0ac20d719bb8
https://pubmed.ncbi.nlm.nih.gov/35789069
https://pubmed.ncbi.nlm.nih.gov/35789069
Publikováno v:
Circulation. Heart failure. 14(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d4a2ac7253e7b1b6031713773714e6
https://pubmed.ncbi.nlm.nih.gov/33706547
https://pubmed.ncbi.nlm.nih.gov/33706547