Zobrazeno 1 - 10
of 1 204
pro vyhledávání: '"Paul A Roberts"'
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 7, p e1007211 (2019)
As antimicrobial resistance increases, it is crucial to develop new treatment strategies to counter the emerging threat. In this paper, we consider combination therapies involving conventional antibiotics and debridement, coupled with a novel anti-ad
Externí odkaz:
https://doaj.org/article/1511297308df432b86c2fbcd0c66cee4
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 5, p e1006071 (2018)
As the development of new classes of antibiotics slows, bacterial resistance to existing antibiotics is becoming an increasing problem. A potential solution is to develop treatment strategies with an alternative mode of action. We consider one such s
Externí odkaz:
https://doaj.org/article/5c8ee5d6c68d4002a44e88eb20181b99
Autor:
David G Wilson, Janet M Lord, John M Morgan, Paul R Roberts, Archana Sharma-Oates, James Sheldon, Daniel F Power
Publikováno v:
Open Heart, Vol 11, Iss 2 (2024)
Objective Most patients who have an implantable cardioverter-defibrillator (ICD) implant do not receive life-prolonging therapy from it. Little research has been undertaken to determine which patients benefit the least from ICD therapy. As patients a
Externí odkaz:
https://doaj.org/article/ec98abc3815047379cb763a5a2a2b0ca
Autor:
Mohamed ElRefai, Mohamed Abouelasaad, Isobel Conibear, Benedict M. Wiles, Anthony J. Dunn, Stefano Coniglio, Alain B. Zemkoho, John Morgan, Paul R. Roberts
Publikováno v:
Indian Pacing and Electrophysiology Journal, Vol 24, Iss 4, Pp 192-199 (2024)
Introduction: The risk of complications associated with transvenous ICDs make the subcutaneous implantable cardiac defibrillator (S-ICD) a valuable alternative in patients with adult congenital heart disease (ACHD). However, higher S-ICD ineligibilit
Externí odkaz:
https://doaj.org/article/c85fe142ff9f4c4aa6ddab6acde043e0
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract In vertebrate vision, early retinal circuits divide incoming visual information into functionally opposite elementary signals: On and Off, transient and sustained, chromatic and achromatic. Together these signals can yield an efficient repre
Externí odkaz:
https://doaj.org/article/49295774890942478da39c86c81fc28a
Autor:
Kirsten E. Lyke, Robert L. Atmar, Clara Dominguez Islas, Christine M. Posavad, Meagan E. Deming, Angela R. Branche, Christine Johnston, Hana M. El Sahly, Srilatha Edupuganti, Mark J. Mulligan, Lisa A. Jackson, Richard E. Rupp, Christina A. Rostad, Rhea N. Coler, Martín Bäcker, Angelica C. Kottkamp, Tara M. Babu, David Dobrzynski, Judith M. Martin, Rebecca C. Brady, Robert W. Frenck, Kumaravel Rajakumar, Karen Kotloff, Nadine Rouphael, Daniel Szydlo, Rahul PaulChoudhury, Janet I. Archer, Sonja Crandon, Brian Ingersoll, Amanda Eaton, Elizabeth R. Brown, M. Juliana McElrath, Kathleen M. Neuzil, David S. Stephens, Diane J. Post, Bob C. Lin, Leonid Serebryannyy, John H. Beigel, David C. Montefiori, Paul C. Roberts, the DMID 21-0012 Study Group
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract As part of a multicenter study evaluating homologous and heterologous COVID-19 booster vaccines, we assessed the magnitude, breadth, and short-term durability of binding and pseudovirus-neutralizing antibody (PsVNA) responses following a sin
Externí odkaz:
https://doaj.org/article/25f04fdb644f4573b07bd819954db49f
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionAbdominal obesity increases the risk of developing ovarian cancer but the molecular mechanisms of how obesity supports ovarian cancer development remain unknown. Here we investigated the impact of obesity on the immune cell and gene expre
Externí odkaz:
https://doaj.org/article/deccb61630694a8c81716c8bae81193e
Autor:
Paul L Roberts, Lynn B Meuleners
Publikováno v:
Journal of Road Safety, Vol 34, Iss 4 (2023)
The evidence for the effectiveness of alcohol interlock programs (AIP) was examined. Interest centred on understanding the individual impact of specific elements that can be incorporated within a program. The overall aim was to formulate the optimal
Externí odkaz:
https://doaj.org/article/75b866eaf05240128b6878e87dc2cdd6
Autor:
Paul R. Roberts, Nicolas Clémenty, Pierre Mondoly, Stefan Winter, Pierre Bordachar, David Sharman, Werner Jung, Romain Eschalier, Cathrin Theis, Pascal Defaye, Christopher Anderson, Aimée Pol, Kiah Butler, Christophe Garweg
Publikováno v:
Journal of Arrhythmia, Vol 39, Iss 1, Pp 1-9 (2023)
Abstract Background While prior Micra trials demonstrated a high implant success rate and favorable safety and efficacy results, changes in implant populations and safety over time is not well studied. The objective of this analysis was to report the
Externí odkaz:
https://doaj.org/article/5ea95a92ac2d429fbf83ad20e6a66921
Autor:
Apostolos Ilias Vouliotis, Paul R Roberts, Polychronis Dilaveris, Konstantinos Gatzoulis, Arthur Yue, Konstantinos Tsioufis
Publikováno v:
European Cardiology Review, Vol 18, Iss , Pp - (2023)
Despite the technological advances in pacemaker technology, the transvenous implanted leads are still considered the Achilles’ heel of this rhythm-control therapy. The leadless permanent pacemaker system was developed as an option to bypass the wea
Externí odkaz:
https://doaj.org/article/3e6d5e0e89494003ac4391b23a38c2ba