Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Paul A Monach"'
Autor:
John H Stone, Peter C Grayson, Ulrich Specks, E William St Clair, Peter A Merkel, Philip Seo, Carol A Langford, Paul A Monach, Cees G M Kallenberg, Robert F Spiera, Fernando C Fervenza, Zuoming Deng, Wei Tew, Marta Casal Moura, Stephen R Brooks, Marco Prunotto
Publikováno v:
RMD Open, Vol 9, Iss 1 (2023)
Background The frequency of proteinase 3 gene (PRTN3) polymorphisms in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is not fully characterised. We hypothesise that the presence of a PRTN3 gene polymorphism (sin
Externí odkaz:
https://doaj.org/article/6bc5f2edf8284a2885c3e9a25bbce574
Autor:
Irena Doubelt, Jason M Springer, Tanaz A Kermani, Antoine G Sreih, Cristina Burroughs, David Cuthbertson, Simon Carette, Nader A Khalidi, Curry L Koening, Carol Langford, Carol A McAlear, Larry W Moreland, Paul A Monach, Dianne G Shaw, Philip Seo, Ulrich Specks, Kenneth J Warrington, Kalen Young, Peter A Merkel, Christian Pagnoux
Publikováno v:
Interactive Journal of Medical Research, Vol 11, Iss 1, p e27273 (2022)
BackgroundPatient-based registries can help advance research on rare diseases such as eosinophilic granulomatosis with polyangiitis (EGPA), a complex multiorgan form of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis. ObjectiveThe
Externí odkaz:
https://doaj.org/article/56119628cf6c4a39a62f8ed95e17f3cc
Autor:
Westyn Branch-Elliman, Ryan Ferguson, Gheorghe Doros, Patricia Woods, Sarah Leatherman, Judith Strymish, Rupak Datta, Rekha Goswami, Matthew D Jankowich, Nishant R Shah, Thomas H Taylor, Sarah T Page, Sara J Schiller, Colleen Shannon, Cynthia Hau, Maura Flynn, Erika Holmberg, Karen Visnaw, Rupali Dhond, Mary Brophy, Paul A Monach
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0263591 (2022)
Importance and objectiveThe aim of this pragmatic, embedded, adaptive trial was to measure the effectiveness of the subcutaneous anti-IL-6R antibody sarilumab, when added to an evolving standard of care (SOC), for clinical management of inpatients wi
Externí odkaz:
https://doaj.org/article/0f93913ce462481c84ad214cf1534dd7
Autor:
Westyn Branch-Elliman, Paul A Monach
Publikováno v:
BMJ Open, Vol 11, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/d5b19a32f2224f5fa4dd03626a0f5f1f
Autor:
Rennie L Rhee, Cecile T J Holweg, Kit Wong, David Cuthbertson, Simon Carette, Nader A Khalidi, Curry L Koening, Carol A Langford, Carol A McAlear, Paul A Monach, Larry W Moreland, Christian Pagnoux, Philip Seo, Ulrich Specks, Antoine G Sreih, Steven R Ytterberg, Peter A Merkel, Vasculitis Clinical Research Consortium
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205768 (2018)
OBJECTIVE:Identification of a biomarker for disease activity in eosinophilic granulomatosis with polyangiitis (EGPA; Churg-Strauss) remains an unmet need. This study examined the value of serum periostin, a marker of type 2 inflammation, as a measure
Externí odkaz:
https://doaj.org/article/5033a7268f404b9498d249f71033979a
Autor:
Jeffrey A Ericson, Pierre Duffau, Kei Yasuda, Adriana Ortiz-Lopez, Katherine Rothamel, Ian R Rifkin, Paul A Monach, ImmGen Consortium
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108553 (2014)
As part of the Immunological Genome Project (ImmGen), gene expression was determined in unstimulated (circulating) mouse neutrophils and three populations of neutrophils activated in vivo, with comparison among these populations and to other leukocyt
Externí odkaz:
https://doaj.org/article/7159cdf3a0fd48d5ab60c771b3e54e3e
Autor:
Paul A Monach, Philipp Kümpers, Alexander Lukasz, Gunnar Tomasson, Ulrich Specks, John H Stone, David Cuthbertson, Jeffrey Krischer, Simon Carette, Linna Ding, Gary S Hoffman, David Iklé, Cees G M Kallenberg, Nader A Khalidi, Carol A Langford, Philip Seo, E William St Clair, Robert Spiera, Nadia Tchao, Steven R Ytterberg, Marion Haubitz, Peter A Merkel
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30197 (2012)
The endothelial-specific Angiopoietin-Tie2 ligand-receptor system is an important regulator of endothelial activation. Binding of angiopoietin-2 (Ang-2) to Tie2 receptor renders the endothelial barrier responsive to pro-inflammatory cytokines. We pre
Externí odkaz:
https://doaj.org/article/371e7fe2baa542ec8cdf3303a02b0857
Autor:
Alvise Berti, Sophie Hillion, Maximilian F. Konig, Marta Casal Moura, Amber M. Hummel, Eva Carmona, Tobias Peikert, Fernando C. Fervenza, Cees G.M. Kallenberg, Carol A. Langford, Peter A. Merkel, Paul A. Monach, Philip Seo, Robert F. Spiera, Paul Brunetta, E. William St. Clair, Kristina M. Harris, John H. Stone, Guido Grandi, Jacques‐Olivier Pers, Ulrich Specks, Divi Cornec
Publikováno v:
Arthritis & Rheumatology. 75:736-747
Autor:
Marta Casal, Moura, Gwen E, Thompson, Darlene R, Nelson, Lynn A, Fussner, Amber M, Hummel, Dieter E, Jenne, Daniel, Emerling, Fernando C, Fervenza, Cees G M, Kallenberg, Carol A, Langford, W Joseph, McCune, Peter A, Merkel, Paul A, Monach, Philip, Seo, Robert F, Spiera, E William, St Clair, Steven R, Ytterberg, John H, Stone, William H, Robinson, Ulrich, Specks
Publikováno v:
Arthritis & Rheumatology. 75:748-759
Proteinase 3 (PR3) is the major antigen for anti-neutrophil cytoplasmic antibodies (ANCAs) in the systemic autoimmune vasculitis, granulomatosis with polyangiitis (GPA). PR3 anti-neutrophil cytoplasmic antibodies (PR3-ANCAs) recognize different epito
Publikováno v:
Annals of Internal Medicine.