Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Paul A LeBlanc"'
Autor:
Cameron F. Leveille, MD, Paul J. LeBlanc, PhD, Kirsten Bott, PhD, Val A. Fajardo, PhD, Adam MacNeil, PhD, Colton Watson, PhD, Sandra Peters, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 1S1, Pp 3-3 (2024)
Externí odkaz:
https://doaj.org/article/7ebd74cf36c4427795723fc05ba1c036
Autor:
Mario Elkes, Martin Andonovski, Daislyn Vidal, Madison Farago, Ryan Modafferi, Steven M. Claypool, Paul J. LeBlanc
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Barth syndrome is a rare and incurable X-linked (male-specific) genetic disease that affects the protein tafazzin (Taz). Taz is an important enzyme responsible for synthesizing biologically relevant cardiolipin (for heart and skeletal muscle, cardiol
Externí odkaz:
https://doaj.org/article/06537801e0544b97ab4ecb65fbb48bac
Autor:
Logan K. Townsend, Kyle D. Medak, Willem T. Peppler, Grace M. Meers, R. Scott Rector, Paul J. LeBlanc, David C. Wright
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1236-1249 (2019)
The relationship between liver interleukin-6 (IL-6) resistance following high-fat diet (HFD)-induced obesity and glucose intolerance is unclear. The purpose of this study was to assess the temporal development of hepatic IL-6 resistance and the role
Externí odkaz:
https://doaj.org/article/90a209a65e0742428bfa9d696f4d8b68
Publikováno v:
Physiological Reports, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Skeletal muscle, a highly active tissue, makes up 40% of the total body weight. This tissue relies on mitochondria for ATP production, calcium homeostasis, and programed cell death. Mitochondrial phospholipid composition, namely, cardiolipin
Externí odkaz:
https://doaj.org/article/6cce560afacd4089ae8063eb301be739
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Background An increase in phosphatidylcholine:phosphatidylethanolamine (PC:PE) and a decrease in fatty acyl chain length, monounsaturated:polyunsaturated (MUFA:PUFA) fatty acyl ratio reduces SERCA activity in liposomes and in mouse models of
Externí odkaz:
https://doaj.org/article/416d17418a164cc491450f01adf87687
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Cardiolipin (CL) is a unique mitochondrial phospholipid that, in skeletal muscle, is enriched with linoleic acid (18:2n6). Together, CL content and CL 18:2n6 composition are critical determinants of mitochondrial function. Skeletal muscle is
Externí odkaz:
https://doaj.org/article/07fa78ef1c5b4708a9f81e1d511beb4e
Autor:
Grant C. Hayward, Paul J. LeBlanc, Craig A. Emter, Jennifer N. K. Nyarko, Darrell D. Mousseau, Rebecca E. K. MacPherson, T. Dylan Olver
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 6 (2019)
Post-menopausal women with heart failure (HF) frequently exhibit cardiogenic dementia. Using a pre-clinical swine model of post-menopausal HF, we recently demonstrated that experimental menopause (ovariectomy; OVX) and HF (6-month cardiac pressure ov
Externí odkaz:
https://doaj.org/article/0292b002735c467fa66638e7c47e6212
Autor:
Paula M. Miotto, Laura M. Castelli, Foyinsola Amoye, Paul J. LeBlanc, Sandra J. Peters, Brian D. Roy, Wendy E. Ward
Publikováno v:
Molecules, Vol 18, Iss 12, Pp 15094-15109 (2013)
High fat diets adversely affect body composition, bone mineral and strength, and alter bone fatty acid composition. It is unclear if maternal high fat (HF) feeding permanently alters offspring body composition and bone health. Female rats were fed co
Externí odkaz:
https://doaj.org/article/73d9a958ffde40fe8d9b1ced5728aa7f
Autor:
Madison Farago, Mario Elkes, Paul J. LeBlanc, Daislyn Vidal, Steven M. Claypool, Ryan Modafferi, Martin Andonovski
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology
Frontiers in Physiology
Barth syndrome is a rare and incurable X-linked (male-specific) genetic disease that affects the protein tafazzin (Taz). Taz is an important enzyme responsible for synthesizing biologically relevant cardiolipin (for heart and skeletal muscle, cardiol
Autor:
Hesham Shamshoum, Logan K. Townsend, David C. Wright, Shivam Gandhi, Jane Shearer, David M. Mutch, Raylene A. Reimer, Sarah K. Trottier, Paul J. LeBlanc
Publikováno v:
Obesity. 28:97-105
Objective This study aimed to explore the individual and combined effects of skim milk powder (SMP) and exercise on indices of systemic and liver lipid metabolism in male obese rats. Methods Rats were fed a high-fat (~ 40% kcal from fat), high-sugar