Zobrazeno 1 - 10
of 556
pro vyhledávání: '"Paul A Dawson"'
Autor:
Catherine Morgan, Stefanie Hennig, Kristen Gibbons, Vicki Flenady, Sailesh Kumar, Pieter Koorts, Nadia Badawi, Roslyn N Boyd, Paul A Dawson, Elizabeth M Hurrion, Manbir Chauhan, Francis Bowling
Publikováno v:
BMJ Open, Vol 13, Iss 7 (2023)
Introduction Antenatal maternal magnesium sulfate (MgSO4) administration is a proven efficacious neuroprotective treatment reducing the risk of cerebral palsy (CP) among infants born preterm. Identification of the neuroprotective component with targe
Externí odkaz:
https://doaj.org/article/4d331488e341434aa1420391157f6938
Autor:
Sumaira Z Hasnain, Paul A Dawson, Rohan Lourie, Peter Hutson, Hui Tong, Richard K Grencis, Michael A McGuckin, David J Thornton
Publikováno v:
PLoS Pathogens, Vol 13, Iss 2, p e1006218 (2017)
Mucins are heavily glycosylated proteins that give mucus its gel-like properties. Moreover, the glycans decorating the mucin protein core can alter the protective properties of the mucus barrier. To investigate whether these alterations could be para
Externí odkaz:
https://doaj.org/article/d0e722c871e24004aa5e86682002a4f0
Autor:
Simon Musyoka Mwangi, Ge Li, Arun Balasubramaniam, Didier Merlin, Paul A. Dawson, Young C. Jang, C. Michael Hart, Mark J. Czaja, Shanthi Srinivasan
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Nonalcoholic fatty liver disease (NAFLD) is associated with increased oxidative stress that leads to hepatocyte and mitochondrial damage. In this study we investigated the mechanisms involved in the induction of oxidative stress and impairme
Externí odkaz:
https://doaj.org/article/556901cf6394459b8308f062a92d5843
Autor:
Rebecca M. Pollak, Ryan H. Purcell, Timothy P. Rutkowski, Tamika Malone, Kimberly J. Pachura, Gary J. Bassell, Michael P. Epstein, Paul A. Dawson, Matthew R. Smith, Dean P. Jones, Michael E. Zwick, Stephen T. Warren, Tamara Caspary, David Weinshenker, Jennifer G. Mulle
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The 1.6 Mb 3q29 deletion is associated with developmental and psychiatric phenotypes, including a 40-fold increased risk for schizophrenia. Reduced birth weight and a high prevalence of feeding disorders in patients suggest underlying metabo
Externí odkaz:
https://doaj.org/article/45761d0ab5754763bcdb5445206f521b
Autor:
Jennifer K. Truong, Ashley L. Bennett, Caroline Klindt, Ajay C. Donepudi, Sudarshan R. Malla, Kimberly J. Pachura, Alex Zaufel, Tarek Moustafa, Paul A. Dawson, Saul J. Karpen
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 9, Pp 100261- (2022)
Cyp2c70 is the liver enzyme in rodents responsible for synthesis of the primary 6-hydroxylated muricholate bile acid (BA) species. Cyp2c70 KO mice are devoid of protective, hydrophilic muricholic acids, leading to a more human-like BA composition and
Externí odkaz:
https://doaj.org/article/c8b1893ec9fd4770aafc4f38f85d3bae
Autor:
Chloe X. Yap, Gail A. Alvares, Anjali K. Henders, Tian Lin, Leanne Wallace, Alaina Farrelly, Tiana McLaren, Jolene Berry, Anna A. E. Vinkhuyzen, Maciej Trzaskowski, Jian Zeng, Yuanhao Yang, Dominique Cleary, Rachel Grove, Claire Hafekost, Alexis Harun, Helen Holdsworth, Rachel Jellett, Feroza Khan, Lauren Lawson, Jodie Leslie, Mira Levis Frenk, Anne Masi, Nisha E. Mathew, Melanie Muniandy, Michaela Nothard, Peter M. Visscher, Paul A. Dawson, Cheryl Dissanayake, Valsamma Eapen, Helen S. Heussler, Andrew J. O. Whitehouse, Naomi R. Wray, Jacob Gratten
Publikováno v:
Molecular Autism, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Background Autism spectrum disorder (ASD) is a complex neurodevelopmental condition whose biological basis is yet to be elucidated. The Australian Autism Biobank (AAB) is an initiative of the Cooperative Research Centre for Living with Autis
Externí odkaz:
https://doaj.org/article/ae37a7b7214449059cff55591f8fa357
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Sulfate is an important nutrient that modulates a diverse range of molecular and cellular functions in mammalian physiology. Over the past 2 decades, animal studies have linked numerous sulfate maintenance genes with neurological phenotypes, includin
Externí odkaz:
https://doaj.org/article/f7d8dd838c914e9287a454327b1b1d6f
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100137- (2021)
Externí odkaz:
https://doaj.org/article/544ba47d2260494281c52b2c79c0a2a7
Autor:
Zhe Zhang, Dhanisha Jhaveri, Sazia Sharmin, Tracey J. Harvey, Paul A. Dawson, Michael Piper, David G. Simmons
Publikováno v:
Biology Open, Vol 9, Iss 7 (2020)
Sulfate is a key anion required for a range of physiological functions within the brain. These include sulfonation of extracellular proteoglycans to facilitate local growth factor binding and to regulate the shape of morphogen gradients during develo
Externí odkaz:
https://doaj.org/article/28905881d46143a29afb999aa9933981
Autor:
Dominick J. Hellen, Ashley Bennett, Sudarshan Malla, Caroline Klindt, Anuradha Rao, Paul A. Dawson, Saul J. Karpen
Publikováno v:
Hepatology. 77:1274-1286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef6b977414d05706eaa0cfd4a957c8a7
https://doi.org/10.1097/hep.0000000000000029
https://doi.org/10.1097/hep.0000000000000029