Zobrazeno 1 - 10
of 574
pro vyhledávání: '"Paul A, Watkins"'
Autor:
Anja Günther, Silke Haverkamp, Stephan Irsen, Paul V. Watkins, Karin Dedek, Henrik Mouritsen, Kevin L. Briggman
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract In most avian retinas, double cones (consisting of a principal and accessory member) outnumber other photoreceptor types and have been associated with various functions, such as encoding luminance, sensing polarized light, and magnetorecepti
Externí odkaz:
https://doaj.org/article/4445fcba464f4782ac7b897989e1c394
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Serial section multibeam scanning electron microscopy (ssmSEM) is currently among the fastest technologies available for acquiring 3D anatomical data spanning relatively large neural tissue volumes, on the order of 1 mm3 or larger, at a resolution su
Externí odkaz:
https://doaj.org/article/28979740c93a48cb83eed7d9a55aa80d
Autor:
Karamarie Fecho, Anne E. Thessen, Sergio E. Baranzini, Chris Bizon, Jennifer J. Hadlock, Sui Huang, Ryan T. Roper, Noel Southall, Casey Ta, Paul B. Watkins, Mark D. Williams, Hao Xu, William Byrd, Vlado Dančík, Marc P. Duby, Michel Dumontier, Gustavo Glusman, Nomi L. Harris, Eugene W. Hinderer, Greg Hyde, Adam Johs, Andrew I. Su, Guangrong Qin, Qian Zhu, The Biomedical Data Translator Consortium
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 8, Pp 1838-1847 (2022)
Abstract Clinical, biomedical, and translational science has reached an inflection point in the breadth and diversity of available data and the potential impact of such data to improve human health and well‐being. However, the data are often siloed
Externí odkaz:
https://doaj.org/article/e60f6adb4b8840dba0f6a5708823c0c0
Autor:
Karamarie Fecho, Chris Bizon, Tursynay Issabekova, Sierra Moxon, Anne E. Thessen, Shervin Abdollahi, Sergio E. Baranzini, Basazin Belhu, William E. Byrd, Lawrence Chung, Andrew Crouse, Marc P. Duby, Stephen Ferguson, Aleksandra Foksinska, Laura Forero, Jennifer Friedman, Vicki Gardner, Gwênlyn Glusman, Jennifer Hadlock, Kristina Hanspers, Eugene Hinderer, Charlotte Hobbs, Gregory Hyde, Sui Huang, David Koslicki, Philip Mease, Sandrine Muller, Christopher J. Mungall, Stephen A. Ramsey, Jared Roach, Irit Rubin, Shepherd H. Schurman, Anath Shalev, Brett Smith, Karthik Soman, Sarah Stemann, Andrew I. Su, Casey Ta, Paul B. Watkins, Mark D. Williams, Chunlei Wu, Colleen H. Xu, The Biomedical Data Translator Consortium
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Knowledge graphs have become a common approach for knowledge representation. Yet, the application of graph methodology is elusive due to the sheer number and complexity of knowledge sources. In addition, semantic incompatibilities hinder efforts to h
Externí odkaz:
https://doaj.org/article/8d108ce3ebbb408b85a7a73670319e07
Autor:
James J. Beaudoin, Kyunghee Yang, Jeffry Adiwidjaja, Guncha Taneja, Paul B. Watkins, Scott Q. Siler, Brett A. Howell, Jeffrey L. Woodhead
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Inhibition of the canalicular phospholipid floppase multidrug resistance protein 3 (MDR3) has been implicated in cholestatic drug-induced liver injury (DILI), which is clinically characterized by disrupted bile flow and damage to the biliary epitheli
Externí odkaz:
https://doaj.org/article/854fa12f4fac4c6c81044b54a6766df4
Developing evidence-based resources for evaluating postgraduate trainees in the biomedical sciences.
Autor:
Jacqueline E McLaughlin, Rebekah L Layton, Paul B Watkins, Robert A Nicholas, Kim L R Brouwer
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0278297 (2022)
Postgraduate trainees elevate the academic strength of institutions by conducting research, promoting innovation, securing grant funding, training undergraduate students, and building alliances. Rigorous and systematic program evaluation can help ens
Externí odkaz:
https://doaj.org/article/406d4b9f66d34db3a70a1f6158406b61
Autor:
Rachel J. Church, Paul B. Watkins
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 2, Pp 434-436 (2021)
Externí odkaz:
https://doaj.org/article/4c8bdd52c399440db70de37c04de439c
Autor:
Herbert L. Bonkovsky, Tyler Severson, Paola Nicoletti, Huiman Barnhart, Jose Serrano, Naga Chalasani, Robert J. Fontana, Paul B. Watkins, Victor Navarro, Andrew Stolz, Ann K. Daly, Guruparasad P. Aithal, Joseph Odin, the US DILIN Investigators
Publikováno v:
Hepatology Communications, Vol 3, Iss 8, Pp 1032-1035 (2019)
With the application of genetic testing to contemporary medical diagnostics and practice, it has become apparent that the phenotypes of many disorders are modulated by host genetic factors. The aim of the current study was to determine whether select
Externí odkaz:
https://doaj.org/article/778afcdb84f24174ade8e85fa6dda32c
Autor:
Paola, Nicoletti, Andrew, Dellinger, Yi Ju, Li, Huiman X, Barnhart, Naga, Chalasani, Robert J, Fontana, Joseph A, Odin, Jose, Serrano, Andrew, Stolz, Amy S, Etheridge, Federico, Innocenti, Olivier, Govaere, Jane I, Grove, Camilla, Stephens, Guruprasad P, Aithal, Raul J, Andrade, Einar S, Bjornsson, Ann K, Daly, M Isabel, Lucena, Paul B, Watkins
Publikováno v:
Gastroenterology. 164:454-466
Drug-induced liver injury (DILI) due to amoxicillin-clavulanate (AC) has been associated with HLA-A*02:01, HLA-DRB1*15:01 and rs2476601, a missense variant in PTPN22. The aim of this study was to identify novel risk factors for AC-DILI and to constru
Autor:
Rachel J. Tyson, Christine C. Park, J. Robert Powell, J. Herbert Patterson, Daniel Weiner, Paul B. Watkins, Daniel Gonzalez
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The administered dose of a drug modulates whether patients will experience optimal effectiveness, toxicity including death, or no effect at all. Dosing is particularly important for diseases and/or drugs where the drug can decrease severe morbidity o
Externí odkaz:
https://doaj.org/article/dc1fb5d6d1e14a9f809d5ca058e1a291