Zobrazeno 1 - 10
of 488
pro vyhledávání: '"Paul A, Janmey"'
Autor:
Giulia Bergamaschi, Andreas S. Biebricher, Hannes Witt, Fitzroy J. Byfield, Xamanie M.R. Seymonson, Cornelis Storm, Paul A. Janmey, Gijs J.L. Wuite
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114852- (2024)
Summary: A quantitative description of nuclear mechanics is crucial for understanding its role in force sensing within eukaryotic cells. Recent studies indicate that the chromatin within the nucleus cannot be treated as a homogeneous material. To elu
Externí odkaz:
https://doaj.org/article/c43b8da926274a51a423a10f299ad7d2
Autor:
Farid Alisafaei, Kalpana Mandal, Renita Saldanha, Maxx Swoger, Haiqian Yang, Xuechen Shi, Ming Guo, Heidi Hehnly, Carlos A. Castañeda, Paul A. Janmey, Alison E. Patteson, Vivek B. Shenoy
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The cytoskeleton is a complex network of interconnected biopolymers consisting of actin filaments, microtubules, and intermediate filaments. These biopolymers work in concert to transmit cell-generated forces to the extracellular matrix requ
Externí odkaz:
https://doaj.org/article/341fa72c1f98498292766d70681e453a
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 6, Pp 251-261 (2023)
Abstract Fat accumulation during liver steatosis precedes inflammation and fibrosis in fatty liver diseases, and is associated with disease progression. Despite a large body of evidence that liver mechanics play a major role in liver disease progress
Externí odkaz:
https://doaj.org/article/9ab82083e59041d1b6845d3a692f3442
Autor:
Łukasz Suprewicz, Kiet A. Tran, Ewelina Piktel, Krzysztof Fiedoruk, Paul A. Janmey, Peter A. Galie, Robert Bucki
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-16 (2022)
Abstract Background Plasma gelsolin (pGSN) is an important part of the blood actin buffer that prevents negative consequences of possible F-actin deposition in the microcirculation and has various functions during host immune response. Recent reports
Externí odkaz:
https://doaj.org/article/443198935aff4306b3fd9dda4e87aa5c
Autor:
Zahra Aliakbar Ahovan, Zahra Esmaeili, Behnaz Sadat Eftekhari, Sadjad Khosravimelal, Morteza Alehosseini, Gorka Orive, Alireza Dolatshahi-Pirouz, Narendra Pal Singh Chauhan, Paul A. Janmey, Ali Hashemi, Subhas C. Kundu, Mazaher Gholipourmalekabadi
Publikováno v:
Materials Today Bio, Vol 17, Iss , Pp 100499- (2022)
Millions of people die annually due to uncured wound infections. Healthcare systems incur high costs to treat wound infections. Tt is predicted to become more challenging due to the rise of multidrug-resistant conditions. During the last decades, sma
Externí odkaz:
https://doaj.org/article/ed849bec8ea54fb19b9c4ffc6ae363d1
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104721- (2022)
Summary: Biomechanical signals from remodeled extracellular matrix (ECM) promote tumor progression. Here, we show that cell-matrix and cell-cell communication may be inherently linked and tuned through mechanisms of mechanosensitive biogenesis of tra
Externí odkaz:
https://doaj.org/article/d15f4b2d8165488f9218c153a8fe0aba
Autor:
Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang, Harun N. Noristani, Dan Li, Jingwen Niu, Shannon Trombley, Jessica I. Goldshteyn, Chuxi Wang, Shuchao Wang, Jingyun Qiu, Katarzyna Pogoda, Kalpana Mandal, Megan Brewster, Panteleimon Rompolas, Ye He, Paul A. Janmey, Gareth M. Thomas, Shuxin Li, Yuanquan Song
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The Atr-Check1 pathway is involved in cell cycle and the DNA damage response. Here, the authors show that the Atr-Check1 pathway can inhibit axon regeneration in response to Piezo-mediated mechanosensation, affecting functional recovery.
Externí odkaz:
https://doaj.org/article/005c24fb0ae4423db9855a4fda43b7ac
Autor:
Robert Bucki, Katarzyna Niemirowicz-Laskowska, Piotr Deptuła, Agnieszka Z. Wilczewska, Paweł Misiak, Bonita Durnaś, Krzysztof Fiedoruk, Ewelina Piktel, Joanna Mystkowska, Paul A. Janmey
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Background Magnetic nanoparticles (MNPs) are characterized by unique physicochemical and biological properties that allow their employment as highly biocompatible drug carriers. Gelsolin (GSN) is a multifunctional actin-binding protein invol
Externí odkaz:
https://doaj.org/article/1d44089628d64e4aaebb20a934cadddd
Autor:
Ewelina Piktel, Urszula Wnorowska, Mateusz Cieśluk, Piotr Deptula, Katarzyna Pogoda, Iwona Misztalewska-Turkowicz, Paulina Paprocka, Katarzyna Niemirowicz-Laskowska, Agnieszka Z. Wilczewska, Paul A. Janmey, Robert Bucki
Publikováno v:
Journal of Nanobiotechnology, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background Human plasma gelsolin (pGSN) is a multifunctional actin-binding protein involved in a variety of biological processes, including neutralization of pro-inflammatory molecules such as lipopolysaccharide (LPS) and lipoteichoic acid (
Externí odkaz:
https://doaj.org/article/64416a4f807b4d2aa2f4b2734da2f3c6
Autor:
Emile A. Kraus, Lauren E. Mellenthin, Sara A. Siwiecki, Dawei Song, Jing Yan, Paul A. Janmey, Alison M. Sweeney
Publikováno v:
Journal of the Royal Society, Interface. 19(195)
Sponges are animals that inhabit many aquatic environments while filtering small particles and ejecting metabolic wastes. They are composed of cells in a bulk extracellular matrix, often with an embedded scaffolding of stiff, siliceous spicules. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18663c72e04decab97b18ce6d54a7ee
https://pubmed.ncbi.nlm.nih.gov/36259170
https://pubmed.ncbi.nlm.nih.gov/36259170